Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 2421-2440 of 5236

    • Synthesis of fluorinated graphene oxide by using an easy one-pot deoxyfluorination reaction 
      Aguilar Bolados, Héctor; Contreras Cid, Ahirton; Yazdani-Pedram Zobeiri, Mehrdad; Acosta Villavicencio, Gabriela; Flores Carrasco, Marcos; Fuentealba, Pablo; Neira Carrillo, Andrónico; Verdejo, Raquel; López Manchado, Miguel (Elsevier, 2018-08-15)
      The fluorination of two types of graphene oxides conducted by an easy and scalable deoxyfluorination reaction is reported. This reaction was carried out using diethylaminodifluorosulfinium tetrafluoroborate, a stable ...
    • Polymeric nanoparticles for increasing oral bioavailability of curcumin 
      Umerska, Anita; Gaucher, Caroline; Oyarzún Ampuero, Felipe; Fries Raeth, Isabelle; Colin, Florence; Villamizar Sarmiento, María Gabriela; Maincent, Philippe; Sapin Minet, Anne (MDPI, 2018-04)
      Despite the promising biological and antioxidant properties of curcumin, its medical applications are limited due to poor solubility in water and low bioavailability. Polymeric nanoparticles (NPs) adapted to oral delivery ...
    • The developmental regulator Pcz1 affects the production of secondary metabolites in the filamentous fungus ... 
      Rojas Aedo, Juan F.; Gil Durán, Carlos; Goity, Alejandra; Vaca Cerezo, Inmaculada; Levican, Gloria; Larrondo, Luis; Chavez, Renato (Elsevier, 2018)
      Penicillium roqueforti is used in the production of several kinds of ripened blue-veined cheeses. In addition, this fungus produces interesting secondary metabolites such as roquefortine C, andrastin A and mycophenolic ...
    • Influence of temperature, calcium and sucrose concentration on viscoelastic properties of prosopis chilensis ... 
      Tabilo Munizaga, Gipsy; Sáenz Hernández, Carmen Luisa; Herrera-Lavados, Carolina (Wiley, 2018-07)
      Viscoelastic properties of two nontraditional hydrocolloid dispersions were evaluated. Prosopis chilensis seed gum was evaluated based on temperature (5-80 degrees C) and added CaCl2 (0.07%), whereas nopal mucilage was ...
    • Fnr and ArcA regulate lipid a hydroxylation in salmonella enteritidis by controlling lpxO expression in ... 
      Fernández, Paulina; Velásquez, Felipe; Garcias-Papayani, Héctor; Amaya, Fernando; Ortega, Jaime; Gómez, Sebastian; Santiviago Cid, Carlos; Álvarez, Sergio A. (Frontiers Media SA., 2018-06)
      Lipid A is the bioactive component of lipopolysaccharide, and presents a dynamic structure that undergoes modifications in response to environmental signals. Many of these structural modifications influence Salmonella ...
    • Synthesis and antioxidant study of new polyphenolic hybrid-coumarins 
      Pérez Cruz, Karina Angélica; Moncada-Basualto, Mauricio; Morales Valenzuela, Javier; Barriga González, Germán; Navarrete Encina, Patricio; Núñez Vergara, Luis; Squella Serrano, Juan; Olea Azar, Claudio (Elsevier, 2018-05)
      The antioxidant capacity of hydroxylated coumarins and hydroxybenzoic acids has been widely described. However, there is little information on the antioxidant activity when both systems are functionalized. In this work, ...
    • Structure-activity study of furyl aryloxazole fluorescent probes for the detection of singlet oxygen 
      Zanocco, Renzo P.; Bresoli-Obach, Roger; Nonell, Santi; Lemp Miranda, Else; Zanocco Loyola, Antonio (Public Library of Science, 2018-07-02)
      In this study, we report the synthesis and the photochemical behavior of a series of new "click-on" fluorescent probes designed to detect singlet oxygen. They include a highly fluorescent chemical structure, an aryloxazole ...
    • Structure-activity relationships based on 3D-QSAR CoMFA/CoMSIA and design of aryloxypropanol-amine agonists ... 
      Lorca, Marcos; Morales Verdejo, César; Vásquez Velásquez, David; Andrades Lagos, Juan Andrés; Campanini Salinas, Javier; Soto Delgado, Jorge; Recabarren Gajardo, Gonzalo; Mella, Jaime (MDPI, 2018)
      The wide tissue distribution of the adrenergic 3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there ...
    • Research on major water and foodborne pathogens in South America: advancements and gaps 
      Adell, Aiko; Rivera, Dacil; Díaz, Constanza; Serrano, María; Toledo, Viviana; Moreno Switt, Andrea (Elsevier, 2018-04)
      The aim of this review was to understand the research that has been conducted in South American countries to detect or quantify major water and foodborne pathogens, with the aim of identifying advancements and gaps in food ...
    • Electrocatalytic oxidation and voltammetric determination of sulfamethazine using a modified carbon elctrode ... 
      Urzúa, L.; Pérez Ortiz, Magdalena; Álvarez Lueje, Alejandro (Sociedad Chilena de Química, 2018-03)
      A carbon paste electrode was modified with the ionic liquid 1-methyl-3-octyl imidazolium hexafluorophosphate and it was applied for study the electrocatalytic oxidation and voltammetric determination of the drug sulfamethazine. ...
    • Methylpiperidinium Iodides as novel antagonists for alpha 7 nicotinic acetylcholine receptors 
      López Villa, Jhon; García Colunga, Jesús; Pérez, Edwin G.; Fierro, Angélica (Frontiers Media, 2018)
      The alpha 7 nicotinic acetylcholine receptor (nAChR) is expressed in neuronal and non-neuronal cells and is involved in several physiopathological processes, and is thus an important drug target. We have designed and ...
    • Identification of peptides in flowers of Sambucus nigra with antimicrobial activity against aquaculture pathogens 
      Álvarez, Claudio; Barriga, Andrés; Albericio, Fernando; Romero, María; Guzman, Fanny (MDPI, 2018-05)
      The elder (Sambucus spp.) tree has a number of uses in traditional medicine. Previous studies have demonstrated the antimicrobial properties of elderberry liquid extract against human pathogenic bacteria and also influenza ...
    • Participación de receptores lectina tipo C en el reconocimiento de hemocianinas de moluscos por células ... 
      Villar Leal, Javiera Paz (2016)
      Las hemocianinas provenientes de los gastrópodos Megathura crenulata, conocida como KLH, Concholepas concholepas (CCH) y Fissurella latimarginata (FLH), presentan propiedades inmunomoduladoras en mamíferos, las cuales han ...
    • Hydrogenation of Multiple Bonds by Geminal Aminoborane-Based Frustrated Lewis Pairs 
      Yepes, Diana; Jaque Olmedo, Pablo; Fernández, Israel (Wiley-VCH, 2018-06-21)
      The hydrogenation reaction of multiple bonds that is mediated by geminal aminoborane-based frustrated Lewis pairs (FLPs) has been explored by means of density functional theory calculations. It was found that the release ...
    • Evaluation of trypanocidal and antioxidant activities of a selected series of 3-amidocoumarins 
      Moncada-Basualto, Mauricio; Lapier, Michel; Maya Arango, Juan; Matsuhiro, Betty; Olea Azar, Claudio; Delogu, Giovanna; Uriarte, Eugenio; Santana, Lourdes; João Matos, María (Bentham Science, 2018)
      Background: Neglected diseases are becoming more prevalent due to globalization. This has inspired active research in the development of new drugs for the treatment of parasitic diseases such as Chagas disease. Objectives: ...
    • Encapsulation of gold nanostructures and oil-in-water nanocarriers in microgels with biomedical potential 
      Inostroza Riquelme, Mariela; Vivanco, Andrea; Lara, Pablo; Guerrero Rivera, Simón; Salas Huenuleo, Edison; Chamorro, Alejandro; Leyton Campos, Lisette; Bolaños, Karen; Araya Fuentes, Eyleen; Quest, Andrew F. G.; Kogan Bocian, Marcelo; Oyarzún Ampuero, Felipe (MDPI, 2018-05)
      Here we report the incorporation of gold nanostructures (nanospheres or nanorods, functionalized with carboxylate-end PEG) and curcumin oil-in-water (O/W) nanoemulsions (CurNem) into alginate microgels using the dripping ...
    • Scanning fluorescence correlation spectroscopy comes full circle 
      Günther Sapunar, Germán; Jameson, David; Aguilar, Joao; Sánchez, Susana (Elsevier, 2018-05-01)
      In this article, we review the application of fluorescence correlation spectroscopy (FCS) methods to studies on live cells. We begin with a brief overview of the theory underlying FCS, highlighting the type of information ...
    • Protection of astaxanthin from photodegradation by its inclusion in hierarchically assembled nano and ... 
      Alarcón-Alarcón, Carlos; Inostroza-Riquelme, Mariela; Torres Gallegos, César; Araya, Claudio; Miranda, Miguel; Sánchez-Caamaño, Juan; Moreno Villoslada, Ignacio; Oyarzún Ampuero, Felipe (Elsevier, 2018-10)
      Astaxanthin is a light sensitive molecule which is already approved as a dietary supplement, with a wide range of biological properties in humans and fishes. In this paper, we provide strategies to photostabilize the pigment ...
    • Tara pod (caesalpinia spinosa) extract mitigates neo-contaminant formation in chilean bread preserving their ... 
      Pedreschi, Franco; Saavedra Gatica, Ilse Elizabeth; Bunger Timmermann, Andrea; Zuiliga, Rommy N.; Pedreschi, Romina; Chirinos, Rosana; Campos, David; Mariotti-Celis, María Salome (Elsevier, 2018-09)
      "Hallulla" is a highly consumed type of Chilean bread, which may contain considerable amounts of some Neo-Formed Contaminants (NFCs). The objective of this research was to study the effect of tara (Caesalpinia spinosa) pod ...
    • Assessment of industrial modules to design a GFMA process for cyanide recovery based on a phenomenological model 
      Estay, Humberto; Troncoso, Elizabeth; Ruby-Figueroa, René; Romero, Julio (MDPI, 2018-04)
      Cyanide recovery in the gold-mining industry is a crucial step in terms of the cost of operation. Currently, a process such as AVR (acidification, volatilization and recycling), based on packed towers for stripping and ...