Browsing by Issue Date Instituto de Nutrición y Tecnología de los Alimentos

Now showing items 321-340 of 923

    • On modelling early life weight trajectories 
      Corvalán Aguilar, Camila (Royal Statistical Society, 2014)
      There is broad recognition that early life growth trajectories can contribute to the study of the onset and development of several health outcomes.We review the random-effects specifications of two models that have been ...
    • Polyphenols and mitochondria: An update on their increasingly emerging ROS-scavenging independent actions 
      Sandoval Acuña, Cristián; Ferreira Parker, Jorge; Speisky Cosoy, Hernán (Elsevier, 2014)
      Polyphenols, ubiquitously present in fruits and vegetables, have been traditionally viewed as antioxidant molecules. Such contention emerged, mainly from their well established in vitro ability to scavenge free radicals ...
    • Predicción de la masa muscular apendicular esquelética basado en mediciones antropométricas en adultos ... 
      Lera Marques, Lydia; Albala Brevis, Cecilia; Angel Badillo, Bárbara Karen; Sánchez Reyes, Hugo; Picrin, Yaisy; Hormázabal, María José; Quiero, Andrea (2014)
      Objetivos: Desarrollar un modelo antropométrico de predicción de masa muscular apendicular esquelética (MMAE), en adultos mayores chilenos. Metodos: La muestra estudiada corresponde a 616 adultos > 60 anos (69,9 +- 5,2 ...
    • Comparative gene expression analysis of Dtg, a novel target gene of Dpp signaling pathway in the early ... 
      Hödar Quiroga, Christian; Zúñiga, Alejandro; Pulgar Tejo, Rodrigo; Travisany, Dante; Chacón, Carlos; Pino, Michael; Maass Sepúlveda, Alejandro; Cambiazo Ayala, Liliana (Elsevier, 2014)
      In the early Drosophila melanogaster embryo, Dpp, a secreted molecule that belongs to the TGF-β superfamily of growth factors, activates a set of downstream genes to subdivide the dorsal region into amnioserosa and ...
    • One-month of calcium supplementation does not affect iron bioavailability: A randomized controlled trial 
      Ríos Castillo, Israel; Olivares Grohnert, Manuel; Brito, Álex; López de Romaña, Daniel; Pizarro Aguirre, Fernando (Elsevier, 2014)
      Objectives: Calcium (Ca) and iron (Fe) are essential minerals for normal growth and development. Although previous studies have shown that Ca inhibits acute Fe absorption, there is no evidence of the possible long- or ...
    • Breast bud detection: a validation study in the Chilean Growth Obesity Cohort Study 
      Pereira Scalabrino, Ana; Garmendia Miguel, María Luisa; Araya González, Daniela; Kain Berkovic, Juliana; Mericq, Verónica; Uauy Dagach-Imbarack, Ricardo; Corvalán Aguilar, Camila (BioMed Central, 2014)
      Background: Early puberty onset has been related to future chronic disease; however breast bud assessment in large scale population studies is difficult because it requires trained personnel. Thus our aim is to assess the ...
    • CCS mRNA transcripts and serum CCS protein as copper marker in adults suffering inflammatory processes 
      Araya, Magdalena; Gutiérrez, Ricardo; Arredondo Olguín, Miguel (Springer, 2014)
      The chaperone to Zn–Cu superoxide dismutase (CCS) has been postulated as a candidate copper indicator, changing in a consistent manner in induced and recovered copper deficiency, in experimental cell and animal models. ...
    • Perception of Neighborhood Crime and Drugs Increases Cardiometabolic Risk in Chilean Adolescents 
      Martinez, Suzanna M.; Blanco, Estela; Delva, Jorge; Burrows, Raquel; Reyes Jedlicki, Marcela; Lozoff, Betsy; Gahagan, Sheila (Elsevier, 2014)
      Purpose: Studies report an association between neighborhood risk and both obesity and cardiometabolic risk factors (CMR) among adolescents. Here we describe the effect of perceived neighborhood risk on adiposity and CMR ...
    • Iron supplementation in infancy contributes to more adaptive behavior at 10 years of age 
      Lozoff, Betsy; Castillo, Marcela; Clark, Katy M.; Smith, Julia B.; Sturza, Julie (ASN, 2014)
      Most studies of behavioral/developmental effects of iron deficiency anemia (IDA) or iron supplementation in infancy have found social-emotional differences. Differences could relate to behavioral inhibition or lack of ...
    • Brain development and scholastic achievement in the Education Quality Measurement System tests in Chilean ... 
      Ivanovic Marincovich, Daniza; Ibaceta, Camila V.; Correa, Paulina B.; Orellana Zapata, Yasna; Calderón, Patricio M.; Morales, Gladys I.; Leyton Dinamarca, Bárbara; Almagià, Atilio F.; Lizana, Pablo A.; Burrows, Raquel (International Pediatric Research Foundation, 2014)
      Background: Head circumference (HC), the anthropometric index of both brain development and nutritional background, has been described to be significantly associated with scholastic achievement (SA). The aim of this ...
    • Assessing chaperone for Zn, Cu-superoxide dismutase as an indicator of copper deficiency in malnourished children 
      Arredondo Olguín, Miguel; Weisstaub Nuta, Sergio; Medina, Marcos; Suazo Romo, Miriam; Guzmán, Miguel; Araya, Magdalena (Elsevier, 2014)
      It is not clear how frequent is copper deficiency in humans. Current copper markers are not sensitive enough to detect early copper deficiency and new markers are needed. CCS is a candidate to become a copper ...
    • Sistema endocanabinoide y desarrollo de esteatosis hepática 
      Valenzuela, Carina; Castillo, Valeska; Ronco Macchiavello, Ana María; Aguirre, Carolina; Hirsch Birn, Sandra; Llanos Silva, Miguel (2014)
      The endocannabinoid system (SEC) is an important modulator of several metabolic functions. This system is composed by cannabinoid receptors type 1 and 2 (RCB1 and RCB2), their endogenous ligands, known as endocannabinoids, and ...
    • Mouse divalent metal transporter 1 is a copper transporter in HEK293 cells 
      Arredondo Olguín, Miguel; Mendiburo Seguel, María José; Flores, Sebastián; Singleton, Steven T.; Garrick, Michael D. (Springer Science+Business Media, 2014)
      Divalent Metal Transporter 1 (DMT1) is an apical Fe transporter in the duodenum and is involved in endosomal Fe export. Four protein isoforms have been described for DMT1, two from mRNA with an iron responsive element ...
    • Evaluación de un programa de educación a distancia en Promoción de Salud para la Atención Primaria en Chile 
      Salinas, Judith; Muñoz, Carolina; Albagli, Andrea; Vio del Río, Fernando Tomás (Universidad de Chile, 2014)
      Background: Health promotion in Chile is essential, considering its current epidemiologic status where chronic diseases are predominant. Aim: To report the evaluation of an on-line Diploma in health promotion for Primary ...
    • Guidelines for diagnosis and treatment of Hunter Syndrome for clinicians in Latin America 
      Giugliani, Roberto; Solano Villarreal, Martha Luz; Arellano Valdez, C. Araceli; Mahfoud Hawilou, Antonieta; Guelbert, Norberto; Correa Garzón, Luz Norela; Martins, Ana María; Acosta, Angelina; Cabello, Juan Francisco; Lemes, Aída; Schmitz Ferreira Santos, Mara Lucía; Amartino, Hernán (Sociedade Brasileira de Genética, 2014)
      This review aims to provide clinicians in Latin America with the most current information on the clinical aspects, diagnosis, and management of Hunter syndrome, a serious and progressive disease for which specific treatment ...
    • Melanocortin-4 receptor polymorphism rs17782313: Association with obesity and eating in the absence of ... 
      Ho Urriola, Judith; Guzmán Guzmán, Iris P; Smalley, Susan V.; González, Andrea; Weisstaub Nuta, Sergio; Domínguez Vásquez, Patricia; Valladares, Macarena; Amador, Paola; Hodgson, María Isabel; Obregón, Ana M.; Santos, José Luis (Elsevier, 2014)
      Objective: The aim of this study was to assess the association between melanocortin-4 receptor (MC4R) rs17782313 alleles with obesity and eating behavior scores in Chilean children. Methods: A case–control study was ...
    • Night time sleep macrostructure is altered in otherwise healthy 10-year-old overweight children 
      Chamorro Melo, Rodrigo; Algarín Crespo, Cecilia; Garrido, M.; Causa Morales, Leonardo Andrés; Held Barrandeguy, Claudio; Lozoff, B.; Peirano Campos, Patricio (Macmillan Publishers Limited, 2014)
      OBJECTIVE: Epidemiological evidence shows an inverse relationship between sleep duration and overweight/obesity risk. However, there are few polysomnographic studies that relate the organization of sleep stages to pediatric ...
    • Changes in the composition and diversity of the bacterial microbiota associated with oysters (Crassostrea ... 
      Trabal Fernández, Natalia; Mazón Suástegui, José M.; Vázquez Juárez, Ricardo; Ascencio Valle, Felipe; Romero Ormazábal, Jaime (Federation of European Microbiological Societies, 2014)
      The resident microbiota of three oyster species (Crassostrea corteziensis, Crassostrea gigas and Crassostrea sikamea) was characterised using a high-throughput sequencing approach (pyrosequencing) that was based on the ...
    • Prenatal Influences on Size, Velocity and Tempo of Infant Growth: Findings from Three Contemporary Cohorts 
      Pizzi, Costanza; Cole, Tim J.; Richiardi, Lorenzo; Dos Santos Silva, Isabel; Corvalán Aguilar, Camila; De Stavola, Bianca (2014)
      Background: Studying prenatal influences of early life growth is relevant to life-course epidemiology as some of its features have been linked to the onset of later diseases. Methods: We studied the association between ...
    • Identification of novel 11b-HSD1 inhibitors by combined ligand- and structure-based virtual screening 
      Lagos, Carlos F.; Vecchiola, Andrea; Allende, Fidel; Fuentes, Cristóbal A.; Tichauer, Juan E.; Valdivia, Carolina; Solari, Sandra; Campino, Carmen; Tapia Castillo, Alejandra; Baudrand, René; Villarroel, Pia; Cifuentes, Mariana; Owen, Gareth I.; Carvajal, Cristian A.; Fardella, Carlos E. (Elsevier, 2014)
      11 beta-hydroxysteroid dehydrogenase type 1 (11b-HSD1) converts cortisone to cortisol in a NADPH dependent manner. Overexpression of 11b-HSD1 in key metabolic tissues is related to the development of type 2 diabetes, ...