Browsing by Title Instituto de Nutrición y Tecnología de los Alimentos

Now showing items 464-483 of 923

    • Identification of Males with Cryptic Fragile X Alleles by Methylation-Specific Quantitative Melt Analysis 
      Aliaga, Solange M.; Slater, Howard R.; Francis, David; Du Sart, Desiree; Li, Xin; Amor, David J.; Alliende, Angelica M.; Santa María Vásquez, Lorena; Faúndes Gómez, Víctor; Morales, Paulina; Trigo, Cesar; Salas, Isabel; Curotto, Bianca; Godler, David E. (Amer. Assoc. Clinical Chemistry, 2016)
      BACKGROUND: FMR1 full mutations (FMs) (CGG expansion >200) in males mosaic for a normal (<45 CGG) or gray-zone (GZ) (45-54 CGG) allele can be missed with the standard 2-step fragile X syndrome (FXS) testing protocols, ...
    • Identification of novel 11b-HSD1 inhibitors by combined ligand- and structure-based virtual screening 
      Lagos, Carlos F.; Vecchiola, Andrea; Allende, Fidel; Fuentes, Cristóbal A.; Tichauer, Juan E.; Valdivia, Carolina; Solari, Sandra; Campino, Carmen; Tapia Castillo, Alejandra; Baudrand, René; Villarroel, Pia; Cifuentes, Mariana; Owen, Gareth I.; Carvajal, Cristian A.; Fardella, Carlos E. (Elsevier, 2014)
      11 beta-hydroxysteroid dehydrogenase type 1 (11b-HSD1) converts cortisone to cortisol in a NADPH dependent manner. Overexpression of 11b-HSD1 in key metabolic tissues is related to the development of type 2 diabetes, ...
    • Identification of woolliness response genes in peach fruit after post-harvest treatments 
      González Agüero, Mauricio; Pávez, Leonardo; Ibáñez, Freddy; Pacheco Blanco, Igor; Campos Vargas, Reinaldo; Meisel, Lee; Orellana López, Ariel; Retamales Aranda, Julio; Silva Ascencio, Herman; González Canales, Mauricio; Cambiazo Ayala, Liliana (2008)
      Woolliness is a physiological disorder of peaches and nectarines that becomes apparent when fruit are ripened after prolonged periods of cold storage. This disorder is of commercial importance since shipping of peaches ...
    • IgA and IgG antitransglutaminase 2 antibodies in the diagnosis of celiac disease 
      Villanueva Choquehuanca, Mónica; Rojas, Marianela; Araya Quezada, María Magdalena (Science and Education Publishing, 2017)
      Screening for celiac disease (CD) dramatically improved when techniques able to measure blood autoantibodies against tissue transglutaminase 2 (TTG) were developed. Although typically increased in CD, these antibodies are ...
    • Impact of a school-based intervention on nutritional education and physical activity in primary public ... 
      Bustos Zapata, Nelly Aracely; Olivares Cortes, Sonia Margarita; Leyton Dinamarca, Bárbara; Cano Cappellacci, Marcelo; Albala Brevis, Cecilia (Cross Mark, 2016)
      Chile has suffered a fast increase in childhood obesity in the last 10 years. As a result, several school programmes have been implemented, however the effectiveness of these needs to be evaluated to identify and prioritize ...
    • Impact of the COVID-19 pandemic on teacher quality of life: a longitudinal study from before and during the ... 
      Lizana, Pablo A.; Vega Fernández, Gustavo; Gómez Bruton, Alejandro; Leyton Dinamarca, Bárbara de Lourdes; Lera Marques, Lydia de la Caridad (MDPI, 2021)
      Background: Prior to the COVID-19 pandemic, teachers were already reporting a low quality of life (QoL) perception, with a significant impact on mental and physical health due to various stress factors associated with work ...
    • Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine 
      Faúndes Gómez, Víctor Manuel; Jennings, Martin D.; Crilly, Siobhan; Legraie, Sarah; Withers, Sarah E.; Cuvertino, Sara; Davies, Sally J.; Douglas L., Andrew G.; Fry, Andrew E.; Harrison, Victoria; Amiel, Jeanne; Lehalle, Daphné; Newman, William G.; Newkirk, Patricia; Ranells, Judith; Splitt, Miranda; Cross, Laura A.; Saunders, Carol J.; Sullivan, Bonnie R.; Granadillo, Jorge L.; Gordon, Christopher T.; Kasher, Paul R.; Pavitt, Graham D.; Banka, Siddharth (Nature, 2021)
      The structure of proline prevents it from adopting an optimal position for rapid protein synthesis. Poly-proline-tract (PPT) associated ribosomal stalling is resolved by highly conserved eIF5A, the only protein to contain ...
    • Implementation of childhood obesity prevention and control policies in the United States and Latin America: ... 
      Pérez Escamilla, Rafael; Vilar Compte, Mireya; Rhodes, Elizabeth; Sarmiento, Olga L.; Corvalán Aguilar, Camila Luz; Sturke, Rachel; Vorkoper, Susan (Wiley, 2021)
      Progress has been made in the development and widespread implementation of effective interventions to address childhood obesity, yet important challenges remain. To understand how the United States and Latin American ...
    • Importancia del uso de métodos actualizados en el control microbiológico de las fórmulas lácteas en ambientes ... 
      Parra Flores, Julio; Maury Sintjago, Eduard; Rodríguez, Alejandra; Soto Acuña, Sergio; Aguirre, Juan; Troncoso Herrera, Miriam; Figueroa Gronemeyer, Guillermo (Sociedad Chilena de Nutrición, 2020)
    • Improving linear growth without excess body fat gain in women and children 
      Uauy Dagach-Imbarack, Ricardo (The United Nations University, 2013)
    • In preschool children, physical activity during school time can significantly increase by intensifying ... 
      Kain Berkovic, Juliana; Leyton Dinamarca, Bárbara; Soto Sánchez, Johana; Concha, Fernando (BioMed Central, 2018)
      Objectives: After categorizing preschool children into “active and low active” according to their moderate and vigor‑ ous physical activity (MVPA) in PE classes (PE), we compared these two groups within each sex and by ...
    • In Vitro Interaction Between Homocysteine and Copper Ions: Potential Redox Implications 
      Carrasco Pozo, Catalina; Álvarez Lueje, Alejandro; Olea Azar, Claudio; López Alarcón, Camilo; Speisky Cosoy, Hernán (SOC EXPERIMENTAL BIOLOGY MEDICINE, 2006-10)
      Homocysteine (Hcys) has been implicated in various oxidative stress–related disorders. The presence of a thiol on its structure allows Hcys to exert a double-edge redox action. Depending on whether Cu2þions occur ...
    • In vitro study of the protective effect of manganese against vanadium mediated nuclear and mitochondrial DNA damage 
      Rivas García, Lorenzo; Quiles, José L.; Varela López, Alfonso; Arredondo Olguín, Miguel; López, Paulina; Rodríguez Diéguez, Antonio; Montes Bayón, María; Aranda, Pilar; Llopis, Juan; Sánchez González, Cristina (Elsevier, 2020)
      We aimed to study the effect of vanadium(V) exposure on cell viability, nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) and to elucidate if these effects can be reverted by co-exposure to V and manganese (Mn). HepG2 cells ...
    • In vivo postprandial bioavailability of interesterified-lipids in sodium-caseinate or chitosan based O/W emulsions 
      Farfán, M.; Villalón, M. J.; Ortíz, M. E.; Nieto K, Susana; Bouchon, P. (Elsevier, 2015)
      Recent studies have shown that it should be possible to control lipid bioavailability through food structural approaches. Nevertheless, the gastrointestinal-tract physiological conditions must also be considered. To get ...
    • Inactivated E. coli transformed with plasmids that produce dsRNA against infectious salmon anemia virus ... 
      Katherin, García; Ramírez Araya, Sebastián; Díaz, Álvaro; Reyes Cerpa, Sebastián; Espejo Torres, Romilio; Higuera, Gastón; Higuera, Gastón; Romero Ormazábal, Jaime (FRONTIERS RESEARCH FOUNDATION, 2015)
      Infectioussalmonanemiavirus(ISAV)hascausedgreatlossestotheChileansalmonindustry,andthesuccessofpreventionandtreatmentstrategiesisuncertain.TheuseofRNAinterference(RNAi)isapromisingapproachbecauseduringthereplicationcycle ...
    • Incidencia de patologías materna de alto riesgo durante el embarazo de acuerdo al estado nutricional al ... 
      Benedetti Ibáñez, Gabriela (Universidad de Chile, 2017-04)
      El objetivo de este estudio fue estimar en una muestra representativa de embarazadas de nivel socio-económico medio-bajo y bajo del área Sur oriente de Santiago la incidencia de las principales patologías maternas que ...
    • Increased adipogenesis of osteoporotic human-mesenchymal stem cells (MSCs) is characterized by impaired ... 
      Astudillo, Pablo; Ríos, Susana; Pastenes, Luis; Pino, Ana María; Rodríguez, J. Pablo (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-03-01)
      The bone marrow contains mesenchymal stem cells (MSCs) that differentiate to the osteogenic and adipogenic lineages. The fact that the decrease in bone volume of age-related osteoporosis is accompanied by an increase in ...
    • Increased dietary availability of selenium in rainbow trout (Oncorhynchus mykiss) improves its plasma ... 
      Pérez Valenzuela, Javiera; Mejías, Madelaine; Ortiz, Daniela; Salgado, Pablo; Montt, Liliana; Chávez Báez, Ignacio; Vera Tamargo, Francisca Valeria; Mandakovic Seyler, Dinka Slavje; Wacyk González, Jurij; Pulgar Tejo, Rodrigo Enrique (BMC, 2021)
      Salmonid Rickettsial Septicaemia (SRS), caused by Piscirickettsia salmonis, is the most important infectious disease in the Chilean salmon farming industry. An opportunity to control this disease is to use functional ...
    • The Increased Expression of Receptor Activator of Nuclear-kappa B Ligand (RANKL) of Multiple Myeloma Bone ... 
      Fernández Gálvez, Mireya; Pino, Ana M.; Figueroa, Paula; Rodríguez, Juan P. (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2010-09-01)
      The receptor activator of nuclear factor-kappaB ligand (RANKL) and interleukin-1beta are osteoclast activating factors which are abnormally expressed in bone marrow stromal cells and plasma cells of multiple myeloma ...
    • Increased levels of metallothionein in placenta of smokers 
      Ronco Macchiavello, Ana María; Argüello, Graciela; Suazo Romo, Miriam; Llanos Silva, Miguel (ELSEVIER SCI IRELAND LTD, 2005-03-01)
      Experiments were designed to evaluate and compare metallothionein (NIT), zinc and cadmium levels in human placentas of smoking and non-smoking women. Smoking was assessed by self-reported cigarette consumption and urine ...