Browsing by Author "Carrasco Pozo, Catalina"
Now showing items 1-7 of 7
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O'Brien, Peter; Carrasco Pozo, Catalina; Speisky Cosoy, Hernán (ELSEVIER, 2006-01-05)The increasing recognition of the participation of free radical-mediated oxidative events in the initiation and/or progression of cardiovascular, tumoural, inflammatory and neurodegenerative disorders, has given rise to ...
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Speisky Cosoy, Hernán; Gómez, Maritza; Carrasco Pozo, Catalina; Pastene, Edgar; López Alarcón, Camilo; Olea Azar, Claudio (PERGAMON-ELSEVIER SCIENCE LTD, 2008-07-01)Cu2+ ions and GSH molecules interact to swiftly form the complex Cu(I)–glutathione. We investigated the potential capacity of such complex to reduce molecular oxygen. The addition of SOD to a solution containing Cu(I)– ...
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Aliaga, Margarita E.; Carrasco Pozo, Catalina; López Alarcón, Camilo; Speisky Cosoy, Hernán (Springer, 2010)Cu2? ions and reduced glutathione (GSH) swiftly interact to form the physiologically occurring Cu(I)–[GSH]2 complex. Prompted by the recently reported ability of this complex to generate superoxide radicals from molecular ...
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Carrasco Pozo, Catalina; Mizgier, María Luisa; Speisky Cosoy, Hernán; Gotteland, Martín (Elsevier, 2012)The beneficial effects of dietary polyphenols on health are due not only to their antioxidant properties but also to their antibacterial, anti-inflammatory and/or anti-tumoral activities. It has recently been proposed that ...
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Carrasco Pozo, Catalina; Aliaga, Margarita E.; Olea Azar, Claudio; Speisky Cosoy, Hernán (PERGAMON-ELSEVIER, 2008-11-15)The present study investigated the redox-consequences of the interaction between various endogenous thiols (RSH)-glutathione, cysteine, homocysteine, c-glutamyl-cysteine, and cysteinyl-glycine-and Cu2+ ions, in terms of ...
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Carrasco Pozo, Catalina; Álvarez Lueje, Alejandro; Olea Azar, Claudio; López Alarcón, Camilo; Speisky Cosoy, Hernán (SOC EXPERIMENTAL BIOLOGY MEDICINE, 2006-10)Homocysteine (Hcys) has been implicated in various oxidative stress–related disorders. The presence of a thiol on its structure allows Hcys to exert a double-edge redox action. Depending on whether Cu2þions occur ...
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Carrasco Pozo, Catalina; Morales, Pamela; Gotteland, Martín (American Chemical Society, 2013)The aim of this study was to determine the protective effect of quercetin, epigallocatechingallate, resveratrol, and rutin against the disruption of epithelial integrity induced by indomethacin in Caco-2 cell monolayers. ...