Browsing by Author "Pino, Ana María"
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Pino, Ana María; Rodríguez, Juan Manuel; Ríos, Susana; Astudillo, Pablo; Leiva, Laura; Seitz, Germán; Fernández Gálvez, Mireya; Rodríguez, J. Pablo (SOC ENDOCRINOLOGY, 2006-12)Human mesenchymal stem cells (hMSCs) are multipotent cells present in bone marrow, which differentiate into osteoblasts and adipocytes, among other lineages. Oestrogens play a critical role in bone metabolism; its action ...
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Pino, Ana María; Ríos, Susana; Astudillo, Pablo; Fernández Gálvez, Mireya; Figueroa, Paula; Seitz, Germán; Rodríguez, J. Pablo (2010-03)Osteoporosis is characterized by low bone mass, microarchitectural deterioration of bone tissue leading to increased bone fragility, and a resulting susceptibility to fractures. Distinctive environmental bone marrow ...
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Torres, Crístian; Antileo, Elmer; Epuñán, María José; Pino, Ana María; Valladares Boasi, Luis; Sierralta, Walter (PROFESSOR D A SPANDIDOS, 2008-06)A cyclic peptide derived from the active domain of α-fetoprotein (AFP) significantly inhibited the proliferation of MCF7 cells stimulated with the epidermal growth factor (EGF) or estradiol (E2). The action of these ...
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Hess, Rodrigo; Pino, Ana María; Ríos, Susana; Fernández Gálvez, Mireya; Rodríguez, J. Pablo (AMER SOC BONE & MINERAL RES., 2004-10)There are disparate observations on central and peripheral effects of leptin, but several studies consistently support its role as a link between fat and bone. Bone marrow stroma contains mesenchymal stem cells (MSCs), ...
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Astudillo, Pablo; Ríos, Susana; Pastenes, Luis; Pino, Ana María; Rodríguez, J. Pablo (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-03-01)The bone marrow contains mesenchymal stem cells (MSCs) that differentiate to the osteogenic and adipogenic lineages. The fact that the decrease in bone volume of age-related osteoporosis is accompanied by an increase in ...