Browsing by Author "Rodríguez, J. Pablo"
Now showing items 1-5 of 5
-
Pino, Ana María; Rodríguez, Juan Manuel; Ríos, Susana; Astudillo, Pablo; Leiva, Laura; Seitz, Germán; Fernández Gálvez, Mireya; Rodríguez, J. Pablo (SOC ENDOCRINOLOGY, 2006-12)Human mesenchymal stem cells (hMSCs) are multipotent cells present in bone marrow, which differentiate into osteoblasts and adipocytes, among other lineages. Oestrogens play a critical role in bone metabolism; its action ...
-
Pino, Ana María; Ríos, Susana; Astudillo, Pablo; Fernández Gálvez, Mireya; Figueroa, Paula; Seitz, Germán; Rodríguez, J. Pablo (2010-03)Osteoporosis is characterized by low bone mass, microarchitectural deterioration of bone tissue leading to increased bone fragility, and a resulting susceptibility to fractures. Distinctive environmental bone marrow ...
-
Hess, Rodrigo; Pino, Ana María; Ríos, Susana; Fernández Gálvez, Mireya; Rodríguez, J. Pablo (AMER SOC BONE & MINERAL RES., 2004-10)There are disparate observations on central and peripheral effects of leptin, but several studies consistently support its role as a link between fat and bone. Bone marrow stroma contains mesenchymal stem cells (MSCs), ...
-
Astudillo, Pablo; Ríos, Susana; Pastenes, Luis; Pino, Ana María; Rodríguez, J. Pablo (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-03-01)The bone marrow contains mesenchymal stem cells (MSCs) that differentiate to the osteogenic and adipogenic lineages. The fact that the decrease in bone volume of age-related osteoporosis is accompanied by an increase in ...
-
Rodríguez, J. Pablo; Montecinos, Luis; Ríos, Susana; Reyes, Patricio; Martínez, Jorge (Wiley-Liss, 2000)Mesenchymal stem cells (MSCs), precursor cells resident in the bone marrow, have the capacity to differentiate into bone, cartilage, fat, and connective tissue. We have recently reported that MSCs from "healthy" donors ...