Browsing by Subject "RU486"

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    • Mifepristone enhances insulin stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells 
      Bernal Sore, Izela; Navarro Márquez, Mario F.; Osorio Fuentealba, César; Díaz Castro, Francisco; Campo, Andrea del; Donoso Barraza, Camila; Porras Espinoza, Omar; Lavandero González, Sergio; Troncoso Cotal, Rodrigo (Elsevier, 2018)
      Mifepristone is the only FDA-approved drug for glycaemia control in patients with Cushing's syndrome and type 2 diabetes. Mifepristone also has beneficial effects in animal models of diabetes and patients with antipsychotic ...
    • Mifepristone for treatment of metabolic syndrome: beyond cushing’s syndrome 
      Díaz Castro, Francisco; Monsalves Álvarez, Matías; Rojo, Leonel E.; Campo, Andrea del; Troncoso, Rodrigo (Frontiers Media, 2020)
      A growing body of research indicates that cortisol, the glucocorticoid product of the activation of the hypothalamic-pituitary-adrenal axis, plays a role in the pathophysiology of metabolic syndrome. In this regard, chronic ...