Browsing by Subject "Pharmacology"
Now showing items 1-20 of 32
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(1991)Boldine shows a concentration-dependent relaxation effect on the rat ileum preparation with a pD2 of 3.77 ± 0.12. The alkaloid also produces a concentration-dependent parallel shift of the curve-response to acetylcholine, ...
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(1993)1. 1. In the present study, adenosine modulation on the antinociceptive action of benzodiazepines (BZD) using the writhing test in mice was evaluated. 2. 2. The i.c.v. BZDs tested (diazepam, midazolam and lorazepam) induced ...
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(1989)1. The analgesic effect of C1X, nifedipine, metamizol, indoprofen and morphine in the pain induced by formalin injection (formalin test) was studied. 2. Attempts to demonstrate tolerance to C1X were unsuccessful. 3. In the ...
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(1992)1. 1. In the present work the analgesic effect of benzodiazepines (BZD) and flumazenil (FLU) using the writhing test in mice was studied. 2. 2. Intracerebroventricular administration of BZD exhibited a dose-dependent ...
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(1993)1. 1. The antinociceptive action of calcium channel blockers administered intracerebroventricularly to mice using the acetic acid writhing test was studied. 2. 2. The drugs produced dose-dependent inhibition of the number ...
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(Informa Healthcare, 1994)Abstractthe antipyretic and antiinflammatory properties of an infusion, a methanol extract, and a purified fraction enriched in sesquiterpenoids, from the aerial parts of maytenus boaria, were evaluated. The fraction ...
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(1983)1. 1. Prazosin, haloperidol, propranolol or timolol had no effect on the electrically evoked muscular twitch. 2. 2. Atropine was able to antagonize competitively acetylcholine (pA2 = 9.29 ± 0.30). 3. 3. The muscular twitch ...
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(1993)1. Liver microsomes from alloxan or streptozotocin diabetic rats displayed differential drug metabolizing abilities in vitro. 2. Only streptozotocin liver microsomes exhibited changes in the cytochrome P-450 normal spectral ...
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(2009)Two Cys-containing analogues of the anticancer drug Kahalalide F are synthesized and conjugated to 20 and 40 nm gold nanoparticles (GNPs). The resulting complexes are characterized by different analytical techniques to ...
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(1991)Kinetic and product studies indicate that the title compound decomposes in aqueous solutions to give 5-nitro-2-aminophenol with the intermediacy of N-(2-hydroxy-4-nitrophenyl)carbamic acid. © 1991.
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(2002)The objective of this work was to develop an educational CD-ROM as a complement to the traditional practical-theoretical teaching of unit operations to pharmacy students. The CD-ROM has five main themes. Three of them ...
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Dissolution kinetics evaluation of controlled-release tablets containing propranolol hydrochloride (Marcel Dekker Inc., 1999)In the present research, controlled-release propranolol hydrochloride tablets were prepared for twice-daily administration, allowing more uniform plasmatic levels of the drug. Pharmaceutical formulations were prepared with ...
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(Informa Healthcare, 1988)A study was done of the effect of blending time on similar mixtures containing nitrofurantoin both in crystalline and macrocrystalline forms. The powder mixture operations were performed using a Twin-Shell Blender (V-type). ...
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(1999)Two sustained-release (SR) lithium carbonate (Li) matrix tablets, which use a hydrophilic (HP) matrix of hydroxypropylmethylcellulose (Methocel 4K MP) and a lipid (L) matrix of hydrogenated castor oil (Cutina HR) as ...
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(1989)1. The cardiovascular effects of CLX were studied. 2. CLX induced hypotension, bradycardia, negative chronotropism and negative inotropism. 3. Electrophysiological studies showed a decrease of sinus venosus discharge ...
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(Marcel Dekker Inc., 1999)Dissolution profiles of theophylline (TP) from three types of sustained- release (SR) matrix tablets (plastic [PL], lipid [LP], and hydrophilic [HP]) in different dissolution media, with and without enzymes, were established. ...
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(1967)Nicotine administered to the isolated perfused heart of the cat produces initial bradycardia followed by long‐lasting tachycardia and enhancement of the strength of contractions. The coronary flow after a reduction shows ...
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(1986)Short or long term alloxan diabetes produced activation of oestrone and morphine glucuronidation and inhibition of p-nitrophenol glucuronidation in rat liver microsomes. Insulin treatment restored decreased glucuronyltransferase ...
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(1986)Solubilities and IR spectra of DIMBOA in alcoholic solvents showed that the carbonyl group of DIMBOA is hydrogen-bonded to the solvent. Activation parameters of DIMBOA in the same solvents suggested that the decomposition ...