Browsing by Author "Squella Serrano, Juan"
Now showing items 101-120 of 177
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(PERGAMON-ELSEVIER SCIENCE, 2000)This paper reports both the electrochemical characterization and the reactivity of the nitroso radical anion from nitrosobenzene with glutathione. The reduction of nitrosobenzene to the corresponding nitroso radical anion ...
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(Sociedade Brasileira de Química, 2010)Substituted chromenos, dihydropyridines and pyridines have been important in the syntheses of compounds having interesting pharmacological properties. Therefore, we found of interest to synthesize chromenopyridines and ...
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(ELECTROCHEMICAL SOC INC, 2008)Electrochemical oxidation of 4-(3-indolyl)- and 4-(5-indolyl)-1,4-dihydropyridines (DHPs) in aprotic and protic media is reported. Also, the reactivity of compounds toward alkylperoxyl radicals 2,2'-azobis-(2-amidinopropane) ...
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(PERGAMON-ELSEVIER SCIENCE, 2007-06-15)This work reports the electrochemical oxidation of three newly synthesized C4-hydroxyphenyl-substituted 1,4-dihydropyridine derivatives in dimethylsulfoxide. The reactivity of the compounds with ABAP-derived alkylperoxyl ...
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(KLUWER ACADEMIC/PLENUM PUBL, 2004-03)The final pyridine derivatives were separated and identified by gas chromatography/ mass spectrometry (GC-MS). The intermediates, anion dihydropyridine and the HO2./HO2- species, were observed from voltammetric studies and ...
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(1988)1. 1. Intestinal clearances of flucloxacillin significantly decrease with the increase of pH, concomitantly with a decrease of the percent absorbed at 60 min. 2. 2. The apparent rate constants for unionized (Ku) and ionized ...
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(1988)The enthalpies of the reaction between glutathione and amoxycillin have been measured directly using a flow microcalorimeter. Comparative results are obtained by using an ac polarographic method previously developed in our ...
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(INST ORGANIC CHEM AND BIOCHEM, ACAD SCI CZECH REPUBLIC, 1991-12)Five N-p-phenyl substituted benzamidines were studied by DC and DP polarography in a wide pH range. Coulometric results show that the overall processes are four-electron reductions. Logarithmic analysis of the waves indicate ...
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(1980)
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(Elsevier B.V., 1996)Loratadine, a potent antihistamine drug, is not directly electroreducible at a dropping mercury electrode; however, by means of a nitration procedure it is possible to obtain a nitro-loratadine derivative which has been ...
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(WILEY-V C H VERLAG GMBH, 2001-07)Megazol (2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0), a highly active compound used against several of Trypanosoma cruzi, the causative agent of Chagas disease, is electrochemically studied ...
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(AMER PHARMACEUTICAL ASSN, 1990)Nifurtimox is polarographically reducible over the whole pH range, the nitro group being reduced to the hydroxylamine group in a 4ē process and subsequently the amine being formed in a 2ē process at a pH value below 4. The ...
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(1992)Nimodipine, a calcium antagonist belonging to the dihydropyridine family, produces a well‐defined polarographic peak due to the four‐electron reduction of the nitro group. This peak was used to track the photodecomposition ...
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(1990)The exposure of drugs to light produces photodecomposition processes in several cases: the drugs undergo important chemical changes with a parallel change in their activities or potencies and generally with a loss of their ...
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(2013)A molecularly imprinted polypyrrole polymer-based film and its properties regarding the recognition of gallic acid were investigated. The polypyrrole film was prepared by including a template molecule during the ...
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(SPRINGER/PLENUM PUBLISHERS, 2005-10)Purpose. The aims of the study are to analyze the interaction between 5-aminosalicylic acid (5-ASA) and peroxyl radicals and to evaluate the effect of some endogenous compounds such as ascorbic acid and amino acids on the ...
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(AMER CHEMICAL SOC, 2003-02)A series of C4-substituted 1,4-dihydropyridines (DHP) with either secondary or tertiary nitrogen in the dihydropyridine ring were synthesized. All of these compounds together with some commercial DHP derivatives were tested ...
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(KLUWER ACADEMIC/PLENUM PUBL, 2004-10)Purpose. To study the reactivity of C4-substituted 1,4-dihydropyridines (1,4-DHP), with either secondary or tertiary nitrogen in the dihydropyridine ring, toward SIN-1-derived peroxynitrite in aqueous media at pH 7.4. Methods. ...
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(2009)Reactivity of two new C4-indolyl substituted 1,4-dihydropyridines (1,4-DHPs) toward superoxide anion (O2-) in dimethylsulfoxide (DMSO) is reported. Reactivity was followed by electrochemical and spectroscopic techniques. ...
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(Sociedad Chilena de Química, 1998)This paper reports the scavenging of the nitro radical anion of nisoldipine by N-acetylcysteine assessed by cyclic volatammetry (CV) and EPR spectroscopic techniques. Studies by CV on the reactivity of the radical were ...
