Now showing items 1017-1036 of 2801

    • Robert Canales, Paz; Torres, Victoria; García Concha, Paula; Vergara Hinostroza, Cristina; Sáenz Hernández, Carmen Luisa (Elsevier, 2015)
      Cactus pear (Opuntia ficus-indica) pulp (CP) was encapsulated with a soybean protein isolate (SPI) and an SPI blend with maltodextrin (MD) or inulin (I). A 22 statistical factorial design for each system (CP-SPI, CP-(SPI ...
    • Antileo, Elmer; Garri, Carolina; Tapia, Victoria; Muñoz, Juan Pablo; Chiong Lay, Mario; Nualart, Francisco; Lavandero González, Sergio; Díaz Fernández, Juan Cristóbal; Núñez González, Marco (American Physiological Society, 2013)
      Ferritin, a food constituent of animal and vegetal origin, is a source of dietary iron. Its hollow central cavity has the capacity to store up to 4,500 atoms of iron, so its potential as an iron donor is advantageous to ...
    • López Crisosto, Camila Paz; Díaz Vegas, Alexis; Castro, Pablo F.; Rothermel, Beverly A.; Bravo Sagua, Roberto Francisco; Lavandero González, Sergio Alejandro (SpringerNature, 2021)
      Subcellular organelles communicate with each other to regulate function and coordinate responses to changing cellular conditions. The physical-functional coupling of the endoplasmic reticulum (ER) with mitochondria allows ...
    • Bravo Sagua, Roberto; Gutiérrez, Tomás; Paredes, Felipe; Gatica, Damián; Rodríguez, Andrea E.; Pedrozo Cibils, Zully; Chiong Lay, Mario; Parra, Valentina; Quest, Andrew F. G.; Rothermel, Beverly A.; Lavandero González, Sergio (Elsevier, 2012)
      Endoplasmic reticulum (ER) stress activates an adaptive unfolded protein response (UPR) that facilitates cellular repair, however, under prolonged ER stress, the UPR can ultimately trigger apoptosis thereby terminating damaged ...
    • Hirsch Birn, Sandra; Maza Cave, María Pía de la; Mendoza, Laura; Petermann, Margarita; Glasinovic, Andrea; Paulinelli, Paola; Barrera, Gladys; Rosenberg, Irwin; Bunout Barnett, Daniel (2002)
      Objetives: To compare endothelium-dependent vasomotor response in healthy younger and older subjects without classic cardiovascular risk factors, with high and normal fasting homocysteine (tHcy) levels. Design: We compared ...
    • Tapia, Julio C.; Niechi, Ignacio (Elsevier Ireland Ltd, 2019)
      The endothelin-1 (ET-1) axis contributes to the pathophysiology of several cancers by promoting tumor development and progression. This peptide is activated from its precursor, big ET-1, by endothelin-converting enzyme-1 ...
    • Morales, Miguel A.; Álvarez, Natalia; Díaz, Andrés J.; Kuoho, Chung Yang; Rodríguez, María P.; Serón, Tomás; Hernández, Doris (2012)
      It was examined the efficacy of Monascus purpureus standardized extract (Mp) on the endothelial dysfunction (ED) of rat aortic rings caused by oxidative stress as a consequence of their exposition to a high glucose ...
    • Morello Casté, Antonio; Letelier, María Eugenia; Aldunate, Jorge; Repetto Scaramelli, Yolanda (Universidad de Chile, 1987)
    • Moglia Fernández, Ítalo Arnoldo; Margarita, Santiago; Guerrero, Simón; Soler Jauma, Mónica; Olivera Nappa, Alvaro María; Kogan, Marcelo Javier (MDPI, 2021)
      Gold nanoparticles (AuNP) capped with biocompatible layers have functional optical, chemical, and biological properties as theranostic agents in biomedicine. The ferritin protein containing in situ synthesized AuNPs has ...
    • Calfumán, Karla; Quezada, Diego; Isaacs, Mauricio; Bollo Dragnic, Soledad (Wiley & Sons, 2015)
      The incorporation of carbon nanotubes to a Nafion/tetraruthenated cobalt porphyrin/glassy carbon electrode (GC/Nf/CoTRP vs GC/Nf/CNTCoTRP) enhanced the amperometric determination of hydrogen peroxide. Both electrodes ...
    • Silva, Eduardo; Herrera, Leonardo; Edwards, Ana María; De la Fuente, Julio; Lissi Gervaso, Eduardo A. (2005)
      We have investigated the riboflavin (RF)-sensitized inactivation of glucose 6-phosphate dehydrogenase (G6PD) in the presence and absence of trans-urocanic acid (UCA). The inactivation of the enzyme results from its direct ...
    • Chávez, H. (Colegio Químico Farmacéutico de Chile, 2000)
      ¿Se ha detenido a pensar la cantidad de tecnología computacional que nos ha invadido los últimos años? Posiblemente ya haya escuchado hablar de electrodomésticos que se conectan a la Internet, y del refrigerador que tiene ...
    • Squella Serrano, Juan; Álvarez Lueje, Alejandro; Sturm,; Núñez Vergara, Luis (1993)
      A differential pulse polarographic method for the identification and quantitative determination of enoxacin is described. The method is based on the electrochemical reduction of the drug at the dropping mercury electrode. ...
    • Latorre, I.; Peña, Raúl C.; Erazo, Silvia (Real Academia de Farmacia, 1990)
      Se realiza un estudio de tres especies de la familia Compositae, incluyendo características morfológicas y muestreo fitoquímico de cada una de ellas. El material fue recolectado en Santiago (Región Metropolitana); las ...
    • Quaglio, Deborah; Mangoni, María Luisa; Stefanelli, Roberta; Corradi, Silvia; Casciaro, Bruno; Vergine, Valeria; Lucantoni, Federica; Cavinato, Luca; Cammarone, Silvia; Loffredo, María Rosa; Cappiello, Floriana; Calcaterra, Andrea; Erazo Giuffra, Silvia; Ghirga, Francesca; Mori, Mattia; Imperi, Francesco; Ascenzioni, Fiorentina; Botta, Bruno (American Chemical Society, 2020)
      Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible ...
    • Pizarro-Oteiza, S; Briones-Labarca, V; Perez-Won, M; Uribe, E; Lemus-Mondaca, R; Canas-Sarazua, R; Tabilo-Munizaga, G (Elsevier Ltd, 2020)
    • Lobos, S.; Tello, Mario; Polanco, R.; Larrondo, L. F.; Manubens, Augusto; Salas, L.; Vicuña E., Rafael (CURRENT SCIENCE ASSN, 2001-10-25)
      Lignin, the most abundant renewable source of aromatic carbon on earth, consists in a highly irregular three-dimensional biopolymer of oxygenated phenylpropanoid units. In natural environments, lignin is only degraded ...
    • Olmedo, Ivonne; Muñoz, Claudia; Guzmán, Nancy; Catalán, Mabel; Vivar, Raúl; Ayala, Pedro; Humeres Martínez, Claudio; Aránguiz, Pablo; García Nannig, Lorena; Velarde, Victoria; Díaz Araya, Guillermo (Elsevier, 2013)
      In the heart, cardiac fibroblasts (CF) and cardiac myofibroblasts (CMF) are the main cells responsible for wound healing after cardiac insult. Exchange protein activated by cAMP (EPAC) is a downstream effector of cAMP, ...
    • Levine, Myron M.; Prado Jiménez, Valeria; Lior, Hermy; Lagos, Rosanna (1996)
    • Kim, Soo Young; Zhang, Xin; Schiattarella, Gabriele G.; Altamirano, Francisco; Ramos, Thais; French, Kristin M.; Jiang, Nan; Szweda, Pamela A.; Evers, Bret M.; May, Herman; Luo, Xiang; Li, Hongliang; Szweda, Luke; Maracajá Coutinho, Vinicius; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Lippincott Williams & Wilkins, 2020)
      BACKGROUND: BET (bromodomain and extraterminal) epigenetic reader proteins, in particular BRD4 (bromodomain-containing protein 4), have emerged as potential therapeutic targets in a number of pathological conditions, ...