Browsing by Title Artículos de revistas

Now showing items 1328-1347 of 2801

    • Improvement of galangin solubility using native and derivative cyclodextrins. An UV-Vis and NMR study 
      Jullian Matthaei, Carolina (2009)
      The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydroxypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ...
    • Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide 
      Riveros Salvatierra, Ana; Eggeling, Cynthia; Riquelme Barrios, Sebastián; Adura, Carolina; López Iglesias, Carmen; Guzmán, Fanny; Araya Fuentes, Eyleen; Almada, Mario; Juárez, Josue; Valdez, Miguel A.; Fuentevilla Morgado, Ignacio; López, Olga; Kogan Bocian, Marcelo (Dove Medical Press, 2020)
      Introduction: Gold nanorods are highly reactive, have a large surface-to-volume ratio, and can be functionalized with biomolecules. Gold nanorods can absorb infrared electromagnetic radiation, which is subsequently dispersed ...
    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide 
      Guerrero, Simon; Araya, Eyleen; Fiedler Temer, Jenny; Arias, J.; Adura, Carolina; Albericio, Fernando; Giralt, Ernest; Arias, José; Fernández, María Soledad; Kogan Bocian, Marcelo (2010)
      Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...
    • In situ Electroreduction of Graphene Oxide: Increased Sensitivity for the Determination of NADH 
      Báez, Daniela F.; Tapia, Felipe; Sierra Rosales, Paulina; Bollo Dragnic, Soledad (Wiley-VCH Verlag, 2019)
      A novel and useful method to catalyze the electro-oxidation of nicotinamide adenine dinucleotide (NADH) over a glassy carbon electrode (GCE) modified with graphene oxide (GO) is presented. Based on the presence of oxygen ...
    • In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl ... 
      Aguirre, G.; Boiani, Lucía; Cerecetto, Hugo; Fernández, M.; González, M.; Denicola, Ana; Otero, L.; Gambino, Dinorah; Rigol Olsen, Carolina; Olea Azar, Claudio; Faúndez Cáceres, Mario Antonio (PERGAMON-ELSEVIER SCIENCE LTD, 2004-09-15)
      The in vitro growth inhibition activity of new thiosemicarbazone derivatives against the protozoan parasite Trypanosoma cruzi, the causative agent of American trypanosomiasis, are described. The designed compounds combine ...
    • In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles 
      Boiani, Lucia; Gerpe, Alejandra; Arán, Vicente; Torres de Ortiz, Susana; Serna, Elva; Vera de Bilbao, Ninfa; Sanabria, Luis; Yaluff, Gloria; Nakayama, Héctor; Rojas de Arias, Antonieta; Maya Arango, Juan; Morello, J.; Cerecetto, Hugo; González, Mercedes (2009)
      Previously, we have identified a series of 5-nitroindazoles with good antiprotozoal activities, against Trypanosoma cruzi epimastigotes and Trichomonas vaginalis. Most of them have shown very low unspecific toxicity on ...
    • In vitro conditions for the study of the in vivo performance of sustained release theophylline matrix tablets ... 
      Andonaegui Álvarez, María Teresa; Barría, J. L.; Thielemann, Ana María; Seitz, C.; Gai, María Nella (MARCEL DEKKER INC, 1999)
      Dissolution profiles of theophylline (TP) from three types of sustained-release (SR) matrix tablets (plastic [PL], lipid [LP], and hydrophilic [HP]) in different dissolution media, with and without enzymes, were established ...
    • In vitro conditions for the study of the in vivo performance of sustained-release theophylline matrix tablets ... 
      Andonaegui,; Barría,; Thielemann,; Seitz,; Gai, (Marcel Dekker Inc., 1999)
      Dissolution profiles of theophylline (TP) from three types of sustained- release (SR) matrix tablets (plastic [PL], lipid [LP], and hydrophilic [HP]) in different dissolution media, with and without enzymes, were established. ...
    • In vitro evolution used to define a protein recognition site within a large RNA domain 
      Sapag, Amalia; Draper, D. E. (PERGAMON-ELSEVIER SCIENCE LTD, 1997-06)
      A minimum of 460 nucleotides of 16S ribosomal RNA are needed to fold the target site for E. coli ribosomal protein S4, although a much smaller region within this large domain is protected from chemical reagents by the ...
    • In vitro sensitivity of Botrytis cinerea to anthraquinone and anthrahydroquinone derivatives 
      Mendoza, Leonora; Araya Maturana, Ramiro; Cardona, Wilson; Delgado Castro, Tomás; García, C.; Lagos, C.; Cotoras, M. (AMER CHEMICAL SOC, 2005-12-28)
      The effect on mycelial growth of the fungus Botrytis cinerea of a set of structurally related tricyclic hydroquinones [9,10-dihydroxy-4,4-dimethyl-2,3,5,8-tetrahydroantracen-1(4H)-one and 9,10-dihydroxy-4,4-dimethyl-5,8- ...
    • In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG (R)) 
      Garrido, Gabino; González, Deyarina; Lemus, Yeny; García, Dagmar; Lodeiro, Lizt; Quintero, Gypsy; Delporte Vergara, Carla; Núñez Sellés, Alberto J.; Delgado, René (ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2004-08)
      A standard aqueous extract of Mangifera indica L., used in Cuba as an antioxidant under the brand name of VIMANG(R), was tested in vivo for its anti-inflammatory activity using commonly accepted assays. M. indica extract, ...
    • In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG®) 
      Garrido, Gabino; González, Deyarina; Lemus, Yeny; García, Dagmar; Lodeiro, Lizt; Quintero, Gypsy; Delporte, Carla; Núñez-Sellés, Alberto J.; Delgado, René (2004)
      A standard aqueous extract of Mangifera indica L., used in Cuba as an antioxidant under the brand name of VIMANG®, was tested in vivo for its anti-inflammatory activity using commonly accepted assays. M. indica extract, ...
    • In vivo and in vitro evidence of basic fibroblast growth factor action in mouse mammary gland development 
      Lavandero González, Sergio; Chappuzeau, A.; Sapag Hagar, Mario; Oka, T. (ELSEVIER SCIENCE BV, 1998-11-20)
      Basic fibroblast growth factor (bFGF) stimulated [H-3]thymidine incorporation at all stages of development, although the magnitude of this effect was the greatest in cells derived from pregnant mice. Cells primed with ...
    • In vivo blockade of acetylcholinesterase increases intraovarian acetylcholine and enhances follicular ... 
      Urra, Javier; Blohberger, Jan; Tiszavari, Michelle; Mayerhofer, Artur; Lara Peñaloza, Hernán (Nature, 2016)
      Growth and differentiation of ovarian follicles are regulated by systemic and local factors, which may include acetylcholine (ACh). Granulosa cells (GCs) of growing follicles and luteal cells produce ACh and in cultured ...
    • In vivo evaluation of two controlled release lithium carbonate tablets 
      Gai, María Nella; Storpirtis, S.; García, P.; Costa, Edda; Thielemann, Ana María; Arancibia, Aquiles (Longman Group, 1992)
      A lithium carbonate controlled release tablet was evaluated in vivo and compared with a conventional lithium carbonate tablet. Changes in the first formulation were made in order to achieve a better performance. The ...
    • Inactivation of glutamine synthetase-coding gene glnA increases susceptibility to quinolones through ... 
      Millanao, Ana; Mora, Aracely; Saavedra, Claudia; Villagra, Nicolás; Mora, Guido; Hidalgo, Alejandro (Frontiers Media, 2020)
      Ciprofloxacin is the choice treatment for infections caused by Salmonella Typhi, however, reduced susceptibility to ciprofloxacin has been reported for this pathogen. Considering the decreased approbation of new antimicrobials ...
    • Incident adverse drug reactions and their effect on the length of hospital stay in older inpatients 
      Sandoval, Tamara; Martínez, Matías; Miranda Olmedo, Fabián; Jirón Aliste, Marcela (Springer, 2020)
      Background Acutely ill older persons are more likely to suffer adverse drug reactions, increasing morbidity, and mortality. The incident adverse drug reactions and their consequences on the length of hospital stay (LOS) ...
    • Inclusion and functionalization of polymers with cyclodextrins: Current applications and future prospects 
      Folch Cano, Christian; Yazdani-Pedram Zobeiri, Mehrdad; Olea Azar, Claudio (MDPI AG, 2014)
      © 2014 Molecules. The numerous hydroxyl groups available in cyclodextrins are active sites that can form different types of linkages. They can be crosslinked with one another, or they can be derivatized to produce monomers ...
    • Inclusion complex of 4-hydroxycoumarin with cyclodextrins and its characterization in aqueous solution 
      Folch Cano, Christian; Olea Azar, Claudio; Sobarzo Sánchez, Eduardo; Alvarez-Lorenzo, Carmen; Concheiro, Angel; Otero, Francisco; Jullian Matthaei, Carolina (2011)
      The physicochemical properties of 4-hydroxy-7-methoxy-3-phenyl-2H-chromen- 2-one (4HC) and β-cyclodextrins (CDs) inclusion complexes were investigated. The phase solubility profile of 4HC with β-cyclodextrin derivatives ...