Browsing by Author "Squella Serrano, Juan"
Now showing items 141-160 of 177
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(Elsevier, 2013)tIn this paper, a series of six dihydropyridine-fused coumarins were synthesized and electrochemicallycharacterized in dimethylformamide (DMF).Dihydropyridine ring oxidation on glassy carbon electrode (GCE) for condensed ...
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(GEORG THIEME VERLAG KG, 2003-12-18)The synthesis and characterization of a series of 4-nitrosophenyl-1.4-dihydropyridines derived from the respective nitro compounds of pharmacological interest is described. The complete synthetic pathway is based on the ...
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(GEORG THIEME VERLAG KG, 2003-12-18)The synthesis and characterization of a series of 4-nitrosophenyl-1.4-dihydropyridines derived from the respective nitro compounds of pharmacological interest is described. The complete synthetic pathway is based on the ...
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(TAYLOR & FRANCIS INC, 2007)A series of C-3,4,5-substituted 2,6-dimethyl-1,4-dihydropyridines ( 1,4-DHPs) with pharmacological properties were prepared by a variation from the classical Hantzsch synthesis. The procedure involves treatment of the ...
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Systematic HPLC study of a new series of 4-methyl-1,4-dihydropyridines with antitrombotic activity (Marcel Dekker Inc., 1998)A systematic study of a new series of 4-methyl-1,4-dihydropyridine derivatives by HPLC by both photodiode array and electrochemical detectors is reported. The optimum mobile phase was acetonitrile/0.05 M phosphate buffer ...
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(Walter de Gruyter GMBH, 2019)C27H21NO4, triclinic, P (1) over bar (no. 2), a = 8.1182(5) angstrom, b = 9.0097(5) angstrom, c = 14.8013(10) angstrom, alpha = 72.603(2)degrees, beta = 82.642(2)degrees, gamma = 79.351(3)degrees, V = 1012.23(11) angstrom(3), ...
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The effect of 5-substitution on the electrochemical behavior and antitubercular activity of PA-824 (PERGAMON-ELSEVIER SCIENCE LTD, 2011-01-15)Nitroimidazole PA-824 is part of an exciting new class of compounds currently undergoing clinical evaluation as novel TB therapeutics. The recently elucidated mechanism of action of PA-824 involves reduction of the ...
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(PERGAMON-ELSEVIER SCIENCE, 2003-03-15)With the aim of determining the actual target(s) of nitro-group bearing compounds considered as possible leads for the development of drugs against Chagas' disease, we studied in parallel nitrofurans and nitroimidazoles. ...
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(ACADEMIC PRESS INC, 2001-09)Chagas' disease constitutes a therapeutic challenge because presently available drugs have wide toxicity to the host and are generally ineffective in the chronic stages of the disease. A series of oxazolo(thiazolo)pyridene ...
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(2005)1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5′-nitro-2′-furyl)-1,4-dihydropyridine derivatives, which were ...
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(SOC BRASILEIRA QUIMICA, 2005-01)1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5'-nitro-2'-furyl)-1,4-dihydropyridine derivatives, which were ...
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(2001)Melatonin and Vitamin B6 can be oxidized at the glassy carbon electrode showing well-resolved anodic peaks by differential pulse voltammetry. Vitamin B6 shows an oxidation peak potential of about 650 mV vs Ag/AgCI in ammonia ...
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(1986)Trazodone, a triazolopyridine derivative with antidepressant activity, is irreversibly oxidized in two steps in a large range of scan rates. The first peak shows a linear dependence on trazodone concentration. This behaviour ...
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Voltammetric behavior and analytical applications of lomefloxacin, an antibacterial fluorquinolone (AOAC INTERNATIONAL, 2001-05)Lomefloxacin was reduced on a dropping mercury electrode, producing one or more peaks, depending on the pH of the aqueous medium. Coulometric measurements gave an experimental value of 1 electron for the main peak. ...
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(Elsevier, 2016)The cyclic voltammetric behavior of 3,5-dinitrobenzoic acid (3,5-DNB) in 0.1 M PBS of pH 7 was examined at a glassy carbon electrode (GCE). 3,5 -DNB was found to produce two irreversible reduction peaks corresponding to ...
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Voltammetric behavior of a 4-nitroimidazole derivative - Nitro radical anion formation and stability (ELECTROCHEMICAL SOC INC, 2005)A new synthesized compound, 1-methyl-4-nitro-2-hydroxymethylimidazole (4-MNImOH), was electrochemically reduced at the mercury electrode in aqueous, mixed, and aprotic media. In an aqueous medium, only one voltammetric ...
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(WILEY-V C H VERLAG GMBH, 2002-09)Lercanidipine is a new third generation 1,4-dihydropyridine calcium antagonist derivative used in hypertension treatments. From the structural point of view lercanidipine contains a nitroaromatic moiety which can be ...
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Voltammetric behavior of zaleplon and its differential pulse polarographic determination in capsules (AOAC INTERNATIONAL, 2005-07)In this work both the electrochemical behavior and the analysis of the hypnotic pyrazolopyrimidine derivative zaleplon were studied. Zaleplon in ethanol-0.1 M Britton Robinson buffer solution (30-70) showed 2 irreversible, ...
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(ELSEVIER SCIENCE BV, 2007-10-31)A complete electrochemical study and a novel electroanalytical procedure for brombexine quantitation are described. Bromhexine in methanol/0.1 mol L-1 Britton-Robinson buffer solution (2.5/97.5) shows an anodic response ...
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Voltammetric behaviour of clonixin and its differential pulse polarographic determination in tablets (MARCEL DEKKER INC, 2000)Clonixin, a non-steroid analgesic, can be both reduced at the mercury electrode and oxidised at the glassy carbon electrode. The anodic response shows well-defined waves in a pH range between pH 2-12. The polarographic ...
