Browsing by Author "Squella Serrano, Juan"
Now showing items 161-177 of 177
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Squella Serrano, Juan; Ordenes, M.; Nocera, F.; Núñez Vergara, Luis; Sunkel, C. (1992)CRE-319, a novel 1,4-dihydropyridine derivative, produces a cathodic polarographic peak due to the reduction of its nitro group according to the following well-known general pathway for the nitro group. The electrode ...
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Squella Serrano, Juan; Lemus, I.; Sturm, J. C.; Núñez Vergara, Luis (Taylor and Francis Inc., 1997)Ketorolac is an antiinflammatory-analgesic agent that is oxidizable at the glassy carbon electrode. The voltammetric oxidation produces two well resolved pH-dependent peaks, that are overlapped at pH>10. Using this ...
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Santander Gutiérrez, Ingrid Paola; Núñez Vergara, Luis; Sturm Schaub, Juan; Squella Serrano, Juan (SOCIEDAD CHILENA DE QUIMICA, 2001-06)Melatonin and Vitamin B6 can be oxidized at the glassy carbon electrode showing well-resolved anodic peaks by differential pulse voltammetry. Vitamin B6 shows an oxidation peak potential of about 650 mV vs Ag/AgCl in ammonia ...
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Jara Ulloa, Paola Andrea; Salgado Figueroa, Paola; Yañez,; Núñez Vergara, Luis; Squella Serrano, Juan (2012)We report the adsorptive voltammetric determination of nifedipine on multiwalled carbon nanotubes (MWCNT)-modified glassy carbon electrode (GCE). Nifedipine was adsorbed on the MWCNT and then reduced using linear sweep and ...
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Yáñez Soto, Claudia; Bollo Dragnic, Soledad; Núñez Vergara, Luis; Squella Serrano, Juan (MARCEL DEKKER, 2001)PA-824 (2-nitro-6-(4-trifluoromethoxy-benzyloxy)-6,7-dihydro-5H-imidazo [2,1-b][1,3]oxazine) a nitroimidazopyran drug candidate for the treatment of tuberculosis was electrochemically studied with the aims of to propose a ...
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Ortíz Yáñez, María Eugenia; Núñez Vergara, Luis; Squella Serrano, Juan (ELSEVIER SCIENCE, 2003-06-05)A detailed investigation on the electrochemical reduction of oxygen was carried out using cyclic voltammetry at a glassy carbon electrode in dimethylsulphoxide (DMSO) containing 0.1 M tetrabutylammonium. perchlorate (TBAP) ...
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López Alarcón, Camilo; Núñez Vergara, Luis; Squella Serrano, Juan (PERGAMON-ELSEVIER SCIENCE, 2003-07-15)A detailed investigation on the electrochemical oxidation of some Hantzsch 1,4-dihydropyridine derivatives with the aim of study the influence of the hydrogen substituent on the N1 position of the heterocyclic ring have ...
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Argüello da Silva, Jacqueline; Núñez Vergara, Luis; Sturm Schaub, Juan; Squella Serrano, Juan (PERGAMON-ELSEVIER SCIENCE, 2004-10-30)A detailed study was done of the electrochemical oxidation of some 1,4-dihydropyridine (1,4-DHP) derivatives in order to determine the influence of the substituents in the heterocyclic ring. Two types of derivatives were ...
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Argüello da Silva, Jacqueline; Núñez Vergara, Luis; Bollo Dragnic, Soledad; Squella Serrano, Juan (ELSEVIER SCIENCE SA, 2006-06-01)To investigate new chemotherapeutics alternatives to Chagas' disease, three 4-(5'-nitro-2'-furyl)-1,4-dihydropyridine derivatives were synthesized and electrochemically investigated in order to clarify their redox behavior. ...
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Bollo Dragnic, Soledad; Jara Ulloa, Paola Andrea; Zapata Torres, Gerald; Cutiño,; Sturm,; Núñez Vergara, Luis; Squella Serrano, Juan (Elsevier Ltd, 2010)The voltammetric reduction of 1-methyl- and 1-H- 4-nitroimidazole derivatives was studied in different protic and aprotic media to investigate the influence of the N-1 substitution in the mechanism of reduction, the ...
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Jara Ulloa, Paola Andrea; Bollo Dragnic, Soledad; Núñez Vergara, Luis; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2008-06)We report the electrochemical behavior of a 4-nitroimidazole derivative, 1-methyl-4-nitro-2-hydroxymethylimidazole (4-NImMeOH), on glassy carbon electrode (GCE) modified with multiwalled carbon nanotubes (MWCNT). As ...
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Álvarez Lueje, Alejandro; Brain Isasi, B.; Núñez Vergara, Luis; Squella Serrano, Juan (ELSEVIER SCIENCE BV, 2008-05-15)Finasteride in hydroalcoholic solutions (ethanol/Britton-Robinson buffer, 30/70) exhibits cathodic response in a wide range of pH (-0.5 to 12) using differential pulse (DPP) and tast polarography (TP). The reduction peak ...
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Carbajo, J.; Bollo Dragnic, Soledad; Núñez Vergara, Luis; Navarrete Encina, Patricio; Squella Serrano, Juan (ELSEVIER SCIENCE, 2000-12-01)In this report we have chosen ethyl-m-nitrobenzoate (EMNB) as a prototype of a nitroaromatic compound in order to carry out a detailed cyclic voltammetric study focused on the coupled chemical reaction of the generated ...
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Núñez Vergara, Luis; Squella Serrano, Juan; Berrios Sagredo, (1983)
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Sturm,; Canelo,; Núñez Vergara, Luis; Squella Serrano, Juan (Elsevier B.V., 1997)A differential pulse polarographic method for the quantitative determination of ketorolac is described. Ketorolac is an antiinflammatory-analgesic agent that is directly electroreducible at the mercury electrode. The ...
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Álvarez Lueje, Alejandro; Vásquez, P.; Núñez Vergara, Luis; Squella Serrano, Juan (Wiley-VCH Verlag, 1997)Nimesulide, N‐(4‐nitro‐2‐phenoxyphenyl)methanesulfonamide is an antiinflamatory analgesic agent that is both reducible at the mercury electrode and oxidizable at the glassy carbon electrode. Nimesulide in hydroalcoholic ...
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Bollo Dragnic, Soledad; Núñez Vergara, Luis; Martínez, C.; Chauviere, G.; Perie, J.; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2003-01)The electrochemical behavior of 2-(5-amino- 1,3,4-oxadiazolyl)-5-nitrofuran (NF359) and its comparison with well known drugs such as nifurtimox (NFX) and nitrofurazone (NFZ) in protic, mixed and aprotic media by cyclic ...