Now showing items 1772-1791 of 2801

    • Otero, Lucía; Vieites, Marisol; Boiani, Lucía; Denicola, Ana; Rigol Olsen, Carolina; Opazo, Lucía; Olea Azar, Claudio; Maya Arango, Juan; Morello Casté, Antonio; Krauth Siegel, R. Luise; Piro, Oscar E.; Castellano, Eduardo; González, Mercedes; Gambino, Dinorah; Cerecetto, Hugo (AMER CHEMICAL SOC, 2006-06-01)
      In the search for new therapeutic tools against American Trypanosomiasis palladium complexes with bioactive nitrofuran-containing thiosemicarbazones as ligands were obtained. Sixteen novel palladium (II) complexes with the ...
    • Uchoa, E. T.; Aguilera, G.; Herman, J. P.; Fiedler Temer, Jenny; Deak, T.; De Sousa, M. B. C. (British Society for Neuroendocrinology, 2014)
      Normal hypothalamic-pituitary-adrenal (HPA) axis activity leading to the rhythmic and episodic release of adrenal glucocorticoids (GCs) is essential for body homeostasis and survival during stress. Acting through specific ...
    • Olea Azar, Claudio; Rigol Olsen, Carolina; Mendizábal Emaldía, Fernando; Cerecetto, Hugo; Di Maio, R.; González, Mercedes; Porcal, Williams; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Maya Arango, Juan (BENTHAM SCIENCE PUBL LTD., 2005-06)
      In order to gain inside the mechanism of action of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives with in vitro anti-trypanosomal activity, electrochemical and biological studies were performed. Cyclic ...
    • Parra, M. L.; Hidalgo, P. I.; Soto Bustamante, Eduardo; Barberá, J.; Elgueta, E. Y.; Trujillo-Rojo, V. H. (2008)
      Novel liquid crystalline materials based on chiral calamitic 1,2,4- and 1,3,4-oxadiazole derivatives were synthesized and their thermotropic mesomorphism investigated by polarizing optical microscopy and differential ...
    • Vega, Andrés; Calvo Pérez, Víctor; Spodine Spiridonova, Evgenia; Zárate, Antonio; Fuenzalida Escobar, Víctor; Saillard, Jean-Yves (2002)
      The reaction of the organometallic carboxylic acid HOOCCCHCo2(CO)6 with copper(II) methoxide leads to a new inorganometallic cluster; Cu3{í2-(CCHCo2(CO)6)}3. This cluster has a triangular core of copper(I) centers ...
    • Galvis Pareja, David; Zapata Torres, Gerald; Hidalgo Tapia, Jorge; Ayala, Pedro; Pedrozo Cibils, Zully; Ibarra, Cristián; Díaz Araya, Guillermo; Hall, Andrew R.; Vicencio, José Miguel; Núñez Vergara, Luis; Lavandero González, Sergio (Elsevier, 2014)
      Rationale: Dihydropyridines are widely used for the treatment of several cardiac diseases due to their blocking activity on L-type Ca2+ channels and their renowned antioxidant properties. Methods: We synthesized six novel ...
    • Calvo Pérez, Víctor; Ostrovsky, Sergei; Vega, Andrés; Pelikan, Juraj; Spodine Spiridonova, Evgenia; Haase, W. (AMER CHEMICAL SOC,, 2006-01-23)
      The trimer [Co-3(mu-OOCCF3)(4)(mu-H2O)(2)(OOCCF3)(2)(H2O)(2)(C4H8O2)]center dot 2C(4)H(8)O(2) (1) is composed of three tetragonally distorted Coll centers bridged by four trifluoroacetates and two bridging water molecules. ...
    • Le Fur, Eric; Pivan, J. Y.; Ushak, S.; Venegas Yazigi, Diego; Spodine Spiridonova, Evgenia (Elsevier, 2008)
      New hybrid organic/inorganic copper oxovanadium compounds of composition [Cu(dpa)(2)](4)V4O12 (1), Cu-2(bipy)(2)V4O12 (2), and Cu-2(bipy)(2)V6O17 (3), which crystallize in the monoclinic 1, 2 and triclinic 3 symmetry, ...
    • Barría, Agustin; Doeschl-Wilson, Andrea B.; Lhorente, Jean Paul; Houston, Ross D.; Yáñez López, José (Elsevier B.V., 2019)
      Breeding for disease resistance has become a highly desirable strategy for mitigating infectious disease problems in aquaculture. However, knowledge of the genetic relationship between resistance and other economically ...
    • Muñoz Córdova, Felipe Andrés; Hernández Fuentes, Carolina; López Crisosto, Camila; Troncoso, Mayarling; Calle Chalco, Ximena Elena; Guerrero Moncayo, Alejandra; Gabrielli, Luigi; Chiong Lay, Mario; Castro, Pablo F.; Lavandero González, Sergio (Frontiers Media, 2021)
      Diabetic cardiomyopathy (DCM) is a severe complication of diabetes developed mainly in poorly controlled patients. In DCM, several clinical manifestations as well as cellular and molecular mechanisms contribute to its ...
    • Arrieta Rodríguez, Loreto; Espinoza Rosales, Daniela; Vera, Gonzalo; Cho, Young Hwa; Cabezas, David; Vásquez Velásquez, David Reinaldo; Mella Raipán, Jaime; Lagos, Carlos F.; Recabarren Gajardo, Gonzalo (MDPI, 2021)
      A new series of twenty-two C-5 substituted N-arylsulfonylindoles was prepared with the aim of exploring the influence of C-5 substitution on 5-HT6 receptor affinity. Eleven compounds showed moderate to high affinity at the ...
    • Morales Montecinos, Javier; Sepúlveda Rivas, Sabrina; Oyarzún Ampuero, Felipe; Lavandero González, Sergio; Kogan Bocian, Marcelo (Bentham, 2015)
      Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have shown recent success. Both intravenous and oral administration have been investigated and achieved different degrees of ...
    • Fernández, Mariana; Rodríguez Arce, Esteban; Sarniguet, Cynthia; Morais, Tânia S.; Tomaz, Ana Isabel; Olea Azar, Claudio; Figueroa, Roberto; Maya Arango, Juan; Medeiros, Andrea; Comini, Marcelo; Garcia, M. Helena; Otero, Lucía; Gambino, Dinorah (Elsevier, 2015)
      Searching for new prospective antitrypanosomal agents, three novel Ru(II)-cyclopentadienyl compounds, [Ru(eta(5)-C5H5)(PPh3)L], with HL = bioactive 5-nitrofuryl containing thiosemicarbazones were synthesized and characterized ...
    • Diaz, C.; Platoni, S.; Molina, A.; Valenzuela, M. L.; Geaney, H.; O'Dwyer, C. (American Scientific Publishers, 2014)
      © 2014 American Scientific Publishers.Solid-state sensor nanostructured materials (SnO2, ZnO and CeO2) have been prepared by pyrolysis of macromolecular complexes: PSP-co-4-PVP · (SnCl2)n, PSP-co-4-PVP · (ZnCl2)nand ...
    • Fernández Oyarzún, Paulina Alejandra; Zabner Espinoza, Marcela Estefanía; Ortega Berríos, Jaime Ignacio; Morgado Ruiz, Constanza Patricia; Amaya Inzunza, Fernando Andrés; Vera Sánchez, Gabriel Alberto; Rubilar Leyton, Carolina Andrea; Salas Valenzuela, Beatriz Elizabeth; Cuevas, Víctor; Valenzuela Montenegro, Camila; Baisón Olmo, Fernando; Álvarez Armijo, Sergio Aníbal; Santiviago Cid, Carlos Alberto (MDPI, 2021)
      The type III secretion systems (T3SS) encoded in pathogenicity islands SPI-1 and SPI-2 are key virulence factors of Salmonella. These systems translocate proteins known as effectors into eukaryotic cells during infection. ...
    • Kerr, Bredford; García Rudaz, Cecilia; Dorfman, Mauricio; Paredes, Alfonso; Ojeda, Sergio R. (2009)
      Recent studies have demonstrated that neurotrophins (NTs) and their NTRK tyrosine kinase receptors, thought to be exclusively required for the development of the nervous system, are also involved in controlling ovarian ...
    • Seelenfreund Hirsch, Daniela; Lobos, S.; Durruty Alfonso, Pilar (Sociedad Chilena de Endocrinología y Diabetes, 2008)
      This review describes the advances in the knowledge about the genetic aspects of common chronic complications of diabetes with prognostic significance, such as diabetic nephropathy and cardiovascular diseases. It is well ...
    • Vega-Gálvez, Antonio; Miranda, Margarita; Vergara, Judith; Uribe, Elsa; Puente, Luis; Martínez, Enrique (2010)
      Quinoa, Chenopodium quinoa Willd., is an Amaranthacean, stress-tolerant plant cultivated along the Andes for the last 7000 years, challenging highly different environmental conditions ranging from Bolivia, up to 4.500 m ...
    • Benavides, S.; Reano, G.; Zúñiga, R. N.; Castillo, O.; Vásquez, F.; Pérez, F.; Mariotti Celis, M. S. (Karger, 2020)
    • ALID, G.; YANEZ, E.; AGUILERA, J. M.; MONCKEBERG, F.; CHICHESTER, C. O. (1981)
      Defatted peanut flour was texturized in a Wenger X‐25 extruder at 25.1% moisture content and 140°C product temperature. Texturization did not have any significant effect on the amino acid pattern nor on the PER of defatted ...