Now showing items 1943-1962 of 2801

    • Squella Serrano, Juan; Sturm,; Diaz, Eloisa; Pessoa,; Núñez Vergara, Luis (Elsevier B.V., 1996)
      Loratadine, a potent antihistamine drug, is not directly electroreducible at a dropping mercury electrode; however, by means of a nitration procedure it is possible to obtain a nitro-loratadine derivative which has been ...
    • Morales, A.; Richter Duk, Pablo; Toral Ponce, María (Royal Society of Chemistry, 1987)
      In pyridine - formic acid buffer and tetramethylammonium chloride solution over the pH range 0-8.5, nitrofurazone, furazolidone and other nitrofuran derivatives are reduced in a six-electron process, giving rise to a well ...
    • Bollo Dragnic, Soledad; Núñez Vergara, Luis; Bontá, M.; Chauviere, G.; Perie, J.; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2001-07)
      Megazol (2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0), a highly active compound used against several of Trypanosoma cruzi, the causative agent of Chagas disease, is electrochemically studied ...
    • Squella Serrano, Juan; Muñoz, W.; Núñez Vergara, Luis; Paulos, Claudio (AMER PHARMACEUTICAL ASSN, 1990)
      Nifurtimox is polarographically reducible over the whole pH range, the nitro group being reduced to the hydroxylamine group in a 4ē process and subsequently the amine being formed in a 2ē process at a pH value below 4. The ...
    • Zanocco Loyola, Antonio; Diaz, L.; Lopez, M.; Núñez Vergara, Luis; Squella Serrano, Juan (1992)
      Nimodipine, a calcium antagonist belonging to the dihydropyridine family, produces a well‐defined polarographic peak due to the four‐electron reduction of the nitro group. This peak was used to track the photodecomposition ...
    • Squella Serrano, Juan; Núñez Vergara, Luis (1990)
      The exposure of drugs to light produces photodecomposition processes in several cases: the drugs undergo important chemical changes with a parallel change in their activities or potencies and generally with a loss of their ...
    • Castro Gálvez, Pablo; Greig, Douglas; Copaja, Miguel; Alcaíno Olivares, Hernán Alejandro; Troncoso Cotal, Rodrigo Hernán; Chiong Lay, Mario; Mellado, Rose Marie; Pérez, Osvaldo; Vukasovic Ramírez, José Luis; Díaz Araya, Guillermo; Corbalán, Ramón; Ocaranza, María Paz; Jalil Milad, Jorge; Lavandero González, Sergio (Sociedad Chilena de Cardilología y Cirugía Cardiovascular, 2005)
      Los polimorfismos de los receptores β Adrenérgicos (AR) influencian el grado de actividad del receptor. Los βAR tienen un rol importante en la regulación de la contractilidad y podrían tener implicancias en el riesgo de ...
    • Santa Ana, María Angélica; Benavente Espinosa, Eglantina; Gómez Romero, Pedro; González Moraga, Guillermo (2006)
      The synthesis, characterization and electrochemistry of a novel nanocomposite based on the co-intercalation of lithium and poly(acrylonitrile) (PAN) in molybdenum disulfide [Li0.6MoS2(PAN) 1.2·0.5H2O] is described. The ...
    • Villar, V.; Opazo, A.; Gargallo, L.; Radić, D.; Rios, H.; Clavijo Campos, Ernesto (Taylor and Francis Inc., 1998)
      Interpolymer complex (IC) formation between poly(ethylene-co-maleic acid) and poly(4-vinylpiridine) (P4VPy) has been observed and characterized. Data from viscosity, infrared spectroscopy and thermogravimetric analysis ...
    • Marambio, Oscar G.; Pizarro, Guadalupe del Carmen; Jeria Orell, Manuel; Huerta, Margarita R.; Olea Azar, Claudio; Habicher, W. D. (0887-624X, 2005-10-15)
      The free-radical copolymerization of N-phenylmaleimide (N-PhMI) with acrylic acid was studied in the range of 25-75 mol % in the feed. The interactions of these copolymers with Cu(H) and Co(H) ions were investigated as a ...
    • Greatti, Vanessa Raquel; Oda, Fernando; Sorrechia, Rodrigo; Kapp, Bárbara Regina; Seraphim, Carolina Manzato; Villas Boas Weckwerth, Ana Carolina; Chorilli, Marlus; Da Silva, Patricia Bento; Eloy, Josimar O.; Kogan, Marcelo J.; Morales Montecinos, Javier; Linhari Rodrigues Pietro, Rosemeire Cristina (MDPI, 2020)
      Dermatophyte fungal infections are difficult to treat because they need long-term treatments. 4-Nerolidylcatechol (4-NC) is a compound found in Piper umbellatum that has been reported to demonstrate significant antifungal ...
    • Leiva, Claudio; Ahumada, Inés; Sepúlveda, Betsabet; Richter Duk, Pablo (ELSEVIER, 2010)
      Assessment of the mobility of polychlorinated biphenyls (PCBs) in soils, amended with biosolids at a rate of 30 Mg ha 1, was performed using an incubation process and leaching columns. The incubation process was carried ...
    • Sienra, María del Rosario; Rosazza, N. G.; Préndez Bolívar, María Margarita (ELSEVIER SCIENCE INC, 2005-06)
      Atmospheric concentrations of polycyclic aromatic hydrocarbons (PAHs) in Santiago de Chile city were evaluated to study particulate PAHs profiles during cold and spring weather periods. Urban atmospheric particulate matter ...
    • Fernández, Carolina; Torrealba, Natalia; Altamirano, Francisco; Garrido Moreno, Valeria Soraya; Vásquez Trincado, César; Flores Vergara, Raúl Alejandro; López Crisosto, Camila; Ocaranza, María Paz; Chiong Lay, Mario Martin; Pedrozo Cibils, Zully Rocío Evangelina; Lavandero González, Sergio (Public Library Science, 2021)
      Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical ...
    • Ramírez Sagredo, Andrea Soledad; Quiroga, Clara; Garrido Moreno, Valeria Soraya; López Crisosto, Camila; Leiva Navarrete, Sebastián Rolando; Norambuena Soto, Ignacio Estebán; Ortiz Quintero, Jose Jafet; Díaz Vesga, Magda C.; Pérez, William; Hendrickson, Troy; Parra Ortiz, Valentina Maria; Pedrozo Cibils, Zully Rocio Evangelina; Altamirano, Francisco; Chiong Lay, Mario Martin; Lavandero Gonzalez, Sergio Alejandro (Wiley, 2021)
      Polycystin-1 (PC1) is a transmembrane protein found in different cell types, including cardiomyocytes. Alterations in PC1 expression have been linked to mitochondrial damage in renal tubule cells and in patients with ...
    • Díaz, C.; Valenzuela, M. L.; Cifuentes Vaca, O.; Segovia, M. (Springer, 2020)
      A mixture of a nanostructured Rh/RhO(2)phase was easily obtained by thermally treating the macromolecular Chitosan center dot(RhCl3)(x)precursor, while the Rh/Rh(2)O(3)phase was obtained by pyrolyzing PSP-4-PVP center ...
    • Díaz Valenzuela, Carlos; Carriedo, Gabino A.; Valenzuela, María Luisa; Zúñiga, Luis; O'Dwyer, Colm (2012)
      The pyrolysis of several physical mixtures of AuCl(PPh 3) with polymeric [NP(O 2C 12H 8)] n or cyclic N 3P 3(O 2C 12H 8) 3 phosphazenes, formed as solid powders or films with different molar ratios, have been studied under ...
    • Atria Salas, Ana María; Parada Aliste, José; Garland, María Teresa; Baggio, Ricardo (2013)
    • Umerska, Anita; Gaucher, Caroline; Oyarzún Ampuero, Felipe; Fries Raeth, Isabelle; Colin, Florence; Villamizar Sarmiento, María Gabriela; Maincent, Philippe; Sapin Minet, Anne (MDPI, 2018-04)
      Despite the promising biological and antioxidant properties of curcumin, its medical applications are limited due to poor solubility in water and low bioavailability. Polymeric nanoparticles (NPs) adapted to oral delivery ...
    • Ocaranza, María Paz; Díaz Araya, Guillermo; Carreño, J. E.; Muñoz, David; Riveros, Juan Pablo; Jalil Milad, Jorge; Lavandero González, Sergio (AMER PHYSIOLOGICAL SOC, 2004-02-01)
      In humans, the effect of angiotensin-converting enzyme (ACE) gene polymorphisms in cardiovascular disease is still controversial. In the rat, a microsatellite marker in the ACE gene allows differentiation of the ACE gene ...