Now showing items 1959-1978 of 2801

    • Díaz Valenzuela, Carlos; Carriedo, Gabino A.; Valenzuela, María Luisa; Zúñiga, Luis; O'Dwyer, Colm (2012)
      The pyrolysis of several physical mixtures of AuCl(PPh 3) with polymeric [NP(O 2C 12H 8)] n or cyclic N 3P 3(O 2C 12H 8) 3 phosphazenes, formed as solid powders or films with different molar ratios, have been studied under ...
    • Atria Salas, Ana María; Parada Aliste, José; Garland, María Teresa; Baggio, Ricardo (2013)
    • Umerska, Anita; Gaucher, Caroline; Oyarzún Ampuero, Felipe; Fries Raeth, Isabelle; Colin, Florence; Villamizar Sarmiento, María Gabriela; Maincent, Philippe; Sapin Minet, Anne (MDPI, 2018-04)
      Despite the promising biological and antioxidant properties of curcumin, its medical applications are limited due to poor solubility in water and low bioavailability. Polymeric nanoparticles (NPs) adapted to oral delivery ...
    • Ocaranza, María Paz; Díaz Araya, Guillermo; Carreño, J. E.; Muñoz, David; Riveros, Juan Pablo; Jalil Milad, Jorge; Lavandero González, Sergio (AMER PHYSIOLOGICAL SOC, 2004-02-01)
      In humans, the effect of angiotensin-converting enzyme (ACE) gene polymorphisms in cardiovascular disease is still controversial. In the rat, a microsatellite marker in the ACE gene allows differentiation of the ACE gene ...
    • Quintanilla González, María Elena; Tampier de Jong, Lutske; Sapag, Amalia; Israel Jacard, Yedy (Lippincott Williams & Wilkins, 2005)
      Dependence on alcohol, a most widely used drug, has a heritability of 50-60%. Wistar-derived rats selectively bred as low-alcohol consumers for many generations present an allele (Aldh22) of mitochondrial aldehyde ...
    • Tapia Castillo, Alejandra; Carvajal, Cristian A.; Campino, Carmen; Vecchiola, Andrea; Allende, Fidel; Solari, Sandra; García Nannig, Lorena; Lavandero González, Sergio; Valdivia, Carolina; Fuentes, Cristobal; Lagos, Carlos F.; Martínez Aguayo, Alejandro; Baudrand, René; Aglony, Marlene; García, Hernán; Fardella, Carlos E. (Oxford University Press, 2014)
      The GTPase Rac1 has been implicated in hypertension as a modulator of mineralocorticoid receptor activity. Our aim is to investigate the frequency of polymorphisms rs10951982 (intron 1, G>A) and rs836478 (intron 3, T>C) ...
    • Cappelli, Claudio; López Cortés, Ximena; Labra, Yohana; Montoya, Margarita; Fernández, Ricardo; Imarai, Mónica; Rojas, Juan Luis; Miranda, Dante; Escobar Alvarez, Alejandro; Acuña Castillo, Claudio (Elsevier, 2012)
      Regulatory T cells (Treg) are important in the development of immune tolerance under normal physiological conditions. However, in pathological situations such as cancer, Treg increases have been correlated with bad ...
    • Brown, Kareen; Car, Pierre Emmanuel; Vega, Andrés; Venegas Yazigi, Diego; Paredes García, Verónica; Vaz, María G.F.; Allao, Rafael A.; Pivan, Jean-Yves; Le Fur, Eric; Spodine Spiridonova, Evgenia (Elsevier, 2011)
      Three compounds based on the polyoxometalate building block [V12B18O60H6], (Na)10[(H2O)V12- B18O60H6] 18H2O (1), Na8[Cu(en)2]2[V12B18O60H6](NO3)2 14.7H2O (2), Na7[Cu(en)2]2[V12B18O60H6] (NO3) 15.5H2O (3), (en = ...
    • Fredes, Carolina; Montenegro, Gloria; Zoffoli, Juan Pablo; Gómez, Miguel; Robert Canales, Paz (Instituto de Investigaciones Agropecuarias, INIA, 2012)
      Maqui (Aristotelia chilensis [Molina] Stuntz, Elaeocarpaceae) is a Chilean native species which produces small berries that are mainly collected from the wild. The health benefts of maqui fruit are attributed to their high ...
    • Jara Ulloa, Paola Andrea; Salgado Figueroa, Paola; Moscoso Cabello, Raúl Andrés; Squella Serrano, Juan (2013)
      A molecularly imprinted polypyrrole polymer-based film and its properties regarding the recognition of gallic acid were investigated. The polypyrrole film was prepared by including a template molecule during the ...
    • Ríos, HernÁn E.; Rojas, Juan S.; Gamboa, Irma C.; Barraza, Raúl O. (1993)
      Four sodium polysoaps from poly[malcic anbydride-co-styrene] were synthesized and the surface properties of their aqueous solutions at the air-water interface were determined. The surface tension lowering was directly ...
    • Escobar Oregón, Leslie Dominique; Andresen, Max; Downey, Patricio; Gai Hernández, María Nella; Regueira, Tomás; Bórquez, Tamara; Lipman, Jeffrey; Roberts, Jason A. (Elsevier, 2014)
      This study aimed to describe the population pharmacokinetics of vancomycin in critically ill patients with refractory septic shock undergoing continuous venovenous high-volume haemofiltration (HVHF) and to define appropriate ...
    • Retuert de la Torre, Pedro Jaime; Quijada Abarca, Juan; Arias, V.; Yazdani-Pedram Zobeiri, Mehrdad (MATERIALS RESEARCH SOCIETY, 2003-02)
      In this paper, we report the preparation by the sol-gel technique of organic-inorganic hybrid composites containing the biopolymer chitosan incorporated in a siloxane-based inorganic network. The hybrid xerogels were ...
    • Letelier Muñoz, María Eugenia; Lepe, Ana María; Faúndez, Mario; Salazar, Julia; Marín Catalán, Rigoberto; Aracena Parks, Paula; Speisky Cosoy, Hernán (ELSEVIER SCI IRELAND, 2005-01-15)
      It is generally accepted that copper toxicity is a consequence of the generation of reactive oxygen species (ROS) by copper ions via Fenton or Haber-Weiss reactions. Copper ions display high affinity for thiol and amino ...
    • Martínez Alvarado, P.; Dagnino Subiabre, Alexies; Paris Pizarro, Irmgard; Metodiewa, D.; Welch, C. J.; Olea Azar, Claudio; Caviedes Fernández, Pablo; Caviedes Codelia, Raúl; Segura Aguilar, Juan (ACADEMIC PRESS INC, 2001-05-25)
      The endogenous dopamine-derived neurotoxin salsolinol was found to decrease survival in the dopaminergic neuronal cell line RCSN-3, derived from adult rat substantia nigra in a concentration-dependent manner (208 muM ...
    • Yunes, Roberto; Estrella, Cecilia R.; García, Sebastián; Lara Peñaloza, Hernán; Cabrera, Ricardo (Hindawi, 2015)
      Ethanol consumption during pregnancy may induce profound changes in fetal CNS development. We postulate that some of the effects of ethanol on striatal glutamatergic transmission and neurotrophin expression could be ...
    • Kettlun, Ana María; Espinosa, V.; García Nannig, Lorena; Valenzuela, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 2005-05)
      Apyrase/ATP-diphosphohydrolase hydrolyzes di- and triphosphorylated nucleosides in the presence of a bivalent ion with sequential release of orthophosphate. We performed studies of substrate specificity on homogeneous ...
    • Aravena, María C.; Olea Azar, Claudio; Cerecetto, Hugo; González, Mercedes; Maya Arango, Juan; Rodríguez Becerra, Jorge (2011)
      Cyclic voltammetry and electron spin resonance techniques were used in the investigation of several potential antiprotozoal containing thiosemicarbazone and carbamate nitrofurans. In the electrochemical behaviour, a ...
    • Vieites, Marisol; Smircich, Pablo; Parajón Costa, Beatriz; Rodríguez Borges, Jorge; Galaz, Verónica; Olea Azar, Claudio; Otero, Lucía; Aguirre, Gabriela; Cerecetto, Hugo; González, Mercedes; Gómez Barrio, Alicia; Garat, Beatriz; Gambino, Dinorah (SPRINGER, 2008-06)
      In the search for new therapeutic tools against Chagas disease (American trypanosomiasis) palladium and platinum complexes of the bioactive ligand pyridine-2- thiol N-oxide were exhaustively characterized and evaluated in ...
    • Castro, Carmen Paz; Henríquez, Olivia; Freres, Rodolfo (2007)
      One of the most negative environmental impacts that have had an explosive growth of Santiago's Metropolitan Region in the last decades, has been the pollution of water courses caused by effluents of waste waters. As a ...