Browsing by Author "Cassels Niven, Bruce"
Now showing items 21-36 of 36
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Weiss López, Boris; Azócar Rangel, Mauricio Alejandro; Montecinos, R.; Cassels Niven, Bruce; Araya Maturana, Ramiro (AMER CHEMICAL SOC, 2001-10-30)Deuterium quadrupole splittings from two series of optical isomers, L- and D-N-acyl-l-phenyl-d(5)-2-aminopropane, with linear acyl chains ranging from I to 10 carbon atoms, were measured using H-2 NMR spectroscopy. Both ...
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Araya Maturana, Ramiro; Delgado Castro, Tomás; Gárate, M.; Ferreira Parker, Jorge; Pavani, M.; Pessoa Mahana, Hernán; Cassels Niven, Bruce (PERGAMON-ELSEVIER SCIENCE LTD, 2002-09)A set of structurally related compounds incorporating a carbonyl group in the ortho position with regard to a phenol function were tested against the TA3 mouse carcinoma cell line and its multidrug-resistant variant ...
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Loghin, Felicia; Chagraoui, Abdeslam; Asencio, Marcelo; Comoy, Etienne; Speisky Cosoy, Hernán; Cassels Niven, Bruce; Protais, Philippe (Elsevier, 2003)(S)-(+)-boldine, an aporphine alkaloid displaying antioxidative and dopaminergic properties, and six of its derivatives (glaucine, 3-bromoboldine, 3-iodoboldine, 8-aminoboldine, 8-nitrosoboldine and 2,9-O,O′-dipivaloylboldine) ...
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Olea Azar, Claudio; Mendizábal Emaldía, Fernando; Alarcón, Jaime; Briones, Rodolfo; Cassels Niven, Bruce; Delgado Castro, Tomás; Araya Maturana, Ramiro (PERGAMON-ELSEVIER SCIENCE LTD, 2001-08)The ESR spectra of radicals obtained by electrolytic reduction of 4,4-dimethylanthracene- 1,9,10 (4H)-trione (1) and the regioisomeric quinones 8-acetyloxymethyl-4,4,5-trimethyl- (2), and 5-acetyloxy-methyl-4,4,8-trimeth ...
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Scorza, Cecilia; Carrau, Cecilia; Silveira, Rodolfo; Zapata Torres, Gerald; Cassels Niven, Bruce; Reyes Parada, Miguel (1997)The monoamine oxidase (MAO) inhibitory properties of a series of amphetamine derivatives with different substituents at or around the para position of the aromatic ring were evaluated. In in vitro studies in which a crude ...
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Sobarzo Sánchez, Eduardo; Saitz Barría, Claudio; Jullian Matthaei, Carolina; Cassels Niven, Bruce (MARCEL DEKKER INC, 2002)The abundant aporphine alkaloid (S)-(+)-boldine (1) was selectively nitrosated with sodium nitrite in acetic acid affording 8-nitrosoboldine (2) which was hydrogenated catalytically to give 8-aminoboldine (3). The latter ...
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Sobarzo Sánchez, Eduardo; Cassels Niven, Bruce; Saitz Barría, Claudio; Jullian Matthaei, Carolina (JOHN WILEY & SONS LTD, 2001-06)The novel heterocycles 1,11-dimethoxy-2-hydroxy-6-methyloxazolo[4,5-k]-5,6,6a,7-tetrahydro-4H-dibenzo [de,g]quinoline, 1,12-dimethoxy-2-hydroxy-6-methyl-9-phenyl-10H-oxazin[5,6-k]-5,6,6a,7-tetrahydro-4H-dibenzo ...
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Zapata Torres, Gerald Amilcar; Cassels Niven, Bruce; Parra Mouchet, Julia; Mascarenhas, Yvonne P.; Ellena, Javier; De Araujo, A. S. (Elsevier Inc, 2008-06)Time-averaged conformations of ( )-1-[3,4-(methylenedioxy)phenyl]-2-methylaminopropane hydrochloride (MDMA, ‘‘ecstasy’’) in D2O, and of its free base and trifluoroacetate in CDCl3, were deduced from their 1H NMR spectra ...
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Asencio,; Cassels Niven, Bruce; Speisky Cosoy, Hernán; Valenzuela, (1993)
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Araya Maturana, Ramiro; Cassels Niven, Bruce; Delgado Castro, Tomás; Valderrama Guerrero, Jaime Adolfo; Weiss López, Boris (PERGAMON-ELSEVIER SCIENCE LTD, 1999-01-15)The Diels-Alder reactions of 8,8-dimethylnaphtalene-1,4,5(8H)-trione with 2,4-hexadien-1-ol and its O-acetyl derivative were investigated in different solvents. The regiochemistry of the cycloaddition of the hexadienol was ...
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Asencio, M.; Cassels Niven, Bruce; Manríquez, V.; Boys, D. (1996)Boldine (5,6,6a,7-tetrahydro- 1,10-dimethoxy-6-methyl- 4H-dibenzo[de,g]quinoline-2,9-diol) is an aporphine alkaloid noted for its antioxidant properties. A salient feature of the molecule is the non-planarity of ...
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Gallardo Godoy, Alejandra; Fierro, Angélica; McLean, Thomas; Castillo, Mariano; Cassels Niven, Bruce; Reyes Parada, Miguel; Nichols, David (2005)A series of phenethylamine derivatives with various ring substituents and with or without N-methyl and/or C-alpha methyl or ethyl groups was synthesized and assayed for their ability reversibly to inhibit monoamine oxidase ...
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Mejías, Lorenzo; Sepúlveda Boza, Silvia; Araya Maturana, Ramiro; Cassels Niven, Bruce; Caroli Rezende, Marcos (Marcel Dekker, Inc., 1998)Methods for the regioselective bromination of the title naphthalenone are described, wich lead to isomeric hydroquinones 5 or 6..
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Aguirre, María C.; Delporte Vergara, Carla; Backhouse Erazo, Nadine; Erazo, Silvia; Letelier Muñoz, María Eugenia; Cassels Niven, Bruce; Silva, Ximena; Alegría, Sergio; Negrete Córdova, Rosa (PERGAMON-ELSEVIER SCIENCE LTD, 2006-08-15)Leaf extracts of Ugni molinae Turcz. are used in the Chilean cosmetic industry on the assumption that they have decongestant, regenerative, and anti-aging properties. A bioassay-guided fractionation of this plant material ...
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Aguirre, María C.; Delporte, Carla; Backhouse, Nadine; Erazo, Silvia; Letelier, María Eugenia; Cassels Niven, Bruce; Silva, Ximena; Alegría, Sergio; Negrete, Rosa (2006)Leaf extracts of Ugni molinae Turcz. are used in the Chilean cosmetic industry on the assumption that they have decongestant, regenerative, and anti-aging properties. A bioassay-guided fractionation of this plant material ...
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Fuentes Barros, Gonzalo; Castro Saavedra, Sebastián; Liberona, Leonel; Acevedo Fuentes, Williams; Tirapegui Calquín, Cristian; Mattar, César; Cassels Niven, Bruce (Elsevier, 2018-06)Eighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents ...