Now showing items 2148-2167 of 2801

    • Cordano, G.; Ferreira, José Roberto; Muñoz, S.; Rivera, E.; Pavani, Mario; Pavez, H. (SOCIEDAD CHILENA DE QUIMICA, 1997-12)
      We report the reaction of gallic acid with chloroacetic acid and three equivalents of sodium hydroxide. In this reaction, 2,6-dihydroxy-4-carboxyphenoxyacetic acid (A) is produced instead of 2,3-dihydroxy-5-carboxyphenoxyacetic ...
    • Pacheco, Camila; González, Estefanía; Robert Canales, Paz; Parada, Javier (Elsevier, 2018)
      Oleuropein is a phenolic compound that is present in fruits and olive tree leaves, which has shown enormous health benefits. This study aimed to assess the effects of the baking and boiling cooking methods and the ...
    • Zapata Torres, Gerald; Fierro, Angélica; Barriga González, Germán; Salgado, J. Cristian; Celis Barros, Cristian (Amer Chemical Soc, 2015)
      Two of the possible catalytic mechanisms for neurotransmitter oxidative deamination by monoamine oxidase B (MAO B), namely, polar nucleophilic and hydride transfer, were addressed in order to comprehend the nature of ...
    • Reyes, Humberto (Blackwell Publishing, 1997)
      Intrahepatic cholestasis of pregnancy is characterized by skin pruritus and a biochemical cholestasis of mild to moderate severity appearing during pregnancy (mainly in the third trimester) and disappearing after delivery. ...
    • Nieves-Aldrey, José Luis; Liljeblad, Johan; Nieves, María Hernández; Grez Villarroel, Audrey; Nylander, Johan A.A. (2009)
      The gall wasp genus Paraulax (Hymenoptera, Cynipidae) associated with southern beeches (Nothofagus (Nothofagaceae)) from South America is revised. The genus Paraulax and its type species, P. perplexa, are redescribed and ...
    • Rodríguez Arce, Esteban; Machado, Ignacio; Rodríguez, Belén; Lapier, Michel; Zúñiga, María Carolina; Maya Arango, Juan; Olea Azar, Claudio; Otero, Lucía; Gambino, Dinorah (Elsevier Inc., 2017)
      © 2017 Elsevier Inc. American Trypanosomiasis is a chronic infection discovered and described in 1909 by the Brazilian scientist Carlos Chagas. It is caused by the protozoan parasite Trypanosoma cruzi. Although it affects ...
    • Enrione, Javier; Char, Cielo; Pepczynska, Marzena; Padilla, Cristina; González Muñoz, Adrián; Olguín, Yusser; Quinzio, Claudia; Iturriaga, Laura; Díaz Calderón, Paulo (MDPI, 2020)
      This study explores the molecular structuring of salmon gelatin (SG) with controlled molecular weight produced from salmon skin, and its relationship with its thermal and rheological properties. SG was produced under di ...
    • Rivera, Paulina; Ocaranza, María Paz; Lavandero González, Sergio; Jalil Milad, Jorge (LIPPINCOTT WILLIAMS & WILKINS, 2007-10)
      The RhoA/Rho kinase (ROCK) pathway is a new mechanism of remodeling and vasoconstriction. Few data are available regarding ROCK activation when angiotensin I-converting enzyme is high and blood pressure is normal. We ...
    • Ocaranza, María Paz; Valderas, Patricio; Moya, Jackeline; Gabrielli, Luigi; Godoy, Iván; Córdava, Samuel; Mac Nab, Paul; García Nannig, Lorena; Farías, Luis; Jalil, Jorge E. (BMC, 2020)
      BackgroundThe intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ...
    • Ocaranza, María Paz; Rivera, Paulina; Novoa, Ulises; Pinto, Melissa; González, Leticia; Chiong Lay, Mario; Lavandero González, Sergio; Jalil Milad, Jorge (LIPPINCOTT WILLIAMS & WILKINS, 2011-04)
      Background Angiotensin II (Ang II) levels depend on renin, angiotensin-converting enzyme (ACE), and on the homologous angiotensin-converting enzyme (ACE2). Increased ACE and Ang II levels are associated with higher Rho ...
    • Ocaranza, María Paz; Moya, Jackeline; Jalil, Jorge E.; Lavandero González, Sergio; Kalergis, Alexis M.; Molina, Cristián; Gabrielli, Luigi; Godoy, Iván; Córdova, Samuel; Castro, Pablo; Mac Nab, Paul; Rossel Mariángel, Víctor; García, Lorena; González, Javier; Mancilla, Cristián; Fierro, Camila; Farías, Luis (Wiley, 2020)
      Background: Increased Rho-kinase activity in circulating leucocytes is observed in heart failure with reduced ejection fraction (HFrEF). However, there is little information in HFrEF regarding other Rho-kinase pathway ...
    • Jalil Milad, Jorge; Lavandero González, Sergio; Chiong Lay, Mario; Ocaranza, María Paz (EDICIONES DOYMA S/L, 2005-08)
      The small guanosine triphosphatase Rho and its target, Rho kinase, play important roles in both blood pressure regulation and vascular smooth muscle contraction. Rho is activated by agonists of receptors coupled to cell ...
    • Boric, M. P.; Figueroa, X. F.; Donoso, M. V.; Paredes Vargas, Alfonso; Poblete, I.; Huidobro Toro, Juan Pablo (AMER PHYSIOLOGICAL SOC, 1999-09)
      To evaluate whether sympathetic activity induces nitric oxide (NO) production, we perfused the rat arterial mesenteric bed and measured luminally accessible norepinephrine (NE), NO, and cGMP before, during, and after ...
    • Faggion, Clovis Mariano; Aranda, Luisiana; Pandis, Nikolaos; Alarcón, Marco Antonio; Diaz, Karla Tatiana (Elsevier Ltd, 2019)
      Objectives: To assess the changes in the risk of bias (RoB) across different versions of the same Cochrane systematic review, and to identify characteristics of systematic reviews which may be associated with different RoB ...
    • Villar Fincheira, Paulina; Sanhueza Olivares, Fernanda; Norambuena Soto, Ignacio; Cancino Arenas, Nicole; Hernández Vargas, Felipe; Troncoso Cotal, Rodrigo; Gabrielli, Luigi; Chiong Lay, Mario (Frontiers Media, 2021)
      IL-6 is usually described as a pleiotropic cytokine produced in response to tissue injury or infection. As a pro-inflammatory cytokine, IL-6 activates innate and adaptative immune responses. IL-6 is released in the innate ...
    • González, Estefanía; Gómez Caravaca, Ana María; Giménez, Begoña; Cebrian, Rubén; Maqueda, Mercedes; Parada, Javier; Martínez Ferez, Antonio; Segura Carretero, Antonio; Paz, Robert (Elsevier, 2020)
      Olive leaves extract (OLE) was spray-dried with maltodextrin (MD) or inulin (IN) to study the evolution of oleuropein (OE) during in vitro gastrointestinal digestion, its bioaccessibility and potential bioavailability. In ...
    • Squicciarini, V.; Riquelme, R.; Wilsterman, K.; Bentley, G. E.; Lara Peñaloza, Hernán (NLM (Medline), 2018)
      2018 Society for Endocrinology RFamide-related peptide (RFRP-3) is a regulator of GnRH secretion from the brain, but it can also act in human ovary to influence steroidogenesis. We aimed to study the putative local role ...
    • Greiner Gebauer, Monika Marcela; Paredes Vargas, Alfonso; Araya, Verónica; Lara Peñaloza, Hernán (HUMANA PRESS INC, 2005-12)
      This article presents a review of the role of the sympathetic activity in ovarian pathologies affecting reproductive function. We provide a succinct outline of the findings of our group in this area. The participation of ...
    • Speisky Cosoy, Hernán; López Alarcón, Camilo; Olea Azar, Claudio; Sandoval-Acua, Cristian; Aliaga, Margarita E. (2011)
      The physiologically occurring copper-glutathione complex, [Cu(I)-[GSH]2], has the ability to react continually with oxygen, generating superoxide anions (O 2 -). We addressed here the effects that superoxide removal has ...
    • Richter Duk, Pablo; Cañas, Alejandro; Muñoz, Carlos; Leiva, Claudio; Ahumada, Inés (2011)
      A novel and very simple microextraction approach for pre-concentration and direct solid phase spectrophotometric measurement has been developed for the determination of chromogenic analytes. The model analyte to assess ...