Browsing by Author "Núñez Vergara, Luis"
Now showing items 41-60 of 74
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(ELSEVIER SCIENCE BV, 2002-09)The effects of some imine and amine derivatives of vanillin on the respiration rate of mouse mammary adenocarcinoma TA3 line, its multiresistant variant TA3-MTX-R line and mouse hepatocytes, together with their respective ...
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(1995)Electrochemical reduction of Ketanserin was studied at different pH and concentrations using polarography and cyclic voltammetry. Ketanserin exhibits two differential pulse polarographic peaks at the dropping mercury ...
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(1989)A method for the differential-pulse polarographic determination of nifedipine has been developed, based on the electrochemistry of the aromatic nitro group in the drug. Polarography has also been used in studies of the ...
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(1997)A series of nitro aryl 1,4-dihydropyridine derivatives produced inhibition of both cell growth and oxygen consumption on Tulahuen and LQ strains, and clone Dm 28c of epimastigotes of Trypanosoma cruzi. Nicardipine was found ...
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(Elsevier, 2014)Rationale: Dihydropyridines are widely used for the treatment of several cardiac diseases due to their blocking activity on L-type Ca2+ channels and their renowned antioxidant properties. Methods: We synthesized six novel ...
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(Sociedade Brasileira de Química, 2010)Substituted chromenos, dihydropyridines and pyridines have been important in the syntheses of compounds having interesting pharmacological properties. Therefore, we found of interest to synthesize chromenopyridines and ...
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(PERGAMON-ELSEVIER SCIENCE, 2007-06-15)This work reports the electrochemical oxidation of three newly synthesized C4-hydroxyphenyl-substituted 1,4-dihydropyridine derivatives in dimethylsulfoxide. The reactivity of the compounds with ABAP-derived alkylperoxyl ...
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(1988)1. 1. Intestinal clearances of flucloxacillin significantly decrease with the increase of pH, concomitantly with a decrease of the percent absorbed at 60 min. 2. 2. The apparent rate constants for unionized (Ku) and ionized ...
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(1988)The enthalpies of the reaction between glutathione and amoxycillin have been measured directly using a flow microcalorimeter. Comparative results are obtained by using an ac polarographic method previously developed in our ...
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(INST ORGANIC CHEM AND BIOCHEM, ACAD SCI CZECH REPUBLIC, 1991-12)Five N-p-phenyl substituted benzamidines were studied by DC and DP polarography in a wide pH range. Coulometric results show that the overall processes are four-electron reductions. Logarithmic analysis of the waves indicate ...
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(1980)
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(Elsevier B.V., 1996)Loratadine, a potent antihistamine drug, is not directly electroreducible at a dropping mercury electrode; however, by means of a nitration procedure it is possible to obtain a nitro-loratadine derivative which has been ...
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(1992)Nimodipine, a calcium antagonist belonging to the dihydropyridine family, produces a well‐defined polarographic peak due to the four‐electron reduction of the nitro group. This peak was used to track the photodecomposition ...
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(1990)The exposure of drugs to light produces photodecomposition processes in several cases: the drugs undergo important chemical changes with a parallel change in their activities or potencies and generally with a loss of their ...
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(1996)The reactivity of the electrochemically generated nitro radical anion from nicardipine, nitrendipine and nimodipine, all nitro aryl 1,4-dihydropyridine derivative, with relevant thiols, was quantitatively assessed by cyclic ...
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(Elsevier Ireland Ltd, 1996)The electrochemical properties of nifuroxazide have been investigated in aqueous and aqueous-DMF mixed solvents. In aqueous media, a single, irreversible four-electron reduction occurs to give the hydroxylamine derivative. ...
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A selective voltammetric method to follow the hydrolytic degradation of nitrendipine and nisoldipine (WILEY-V C H VERLAG GMBH, 2001-12)The development and application of a differential pulse voltammetric procedure for the hydrolytic degradation kinetic study of two well-known 1,4-dihydropyridine type drugs, nitrendipine and nisoldipine are presented. The ...
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(WILEY-V C H VERLAG GMBH, 2004-04)Spectroelectrochemical and HPLC characterization of the electrochemical oxidation in aqueous medium of a series of six N-1 and C-4 substituted 1,4-dihydropyridines is presented. Based on the analysis of spectra obtained ...
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(2004)Inclusion complexation between furnidipine (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-tetrahydrofurfuryl 5-methyl diester), a calcium-channel antagonist, and beta-cyclodextrin (beta-CyD) ...
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(The American Society of Photobiology, 2014)The electronic nature of substituents attached to the 4-aryl moiety of 1,4-dihydropyridines strongly affects the photophysical and photochemical behavior of these family of compounds. The presence of an electron donor ...
