Browsing by Author "Olea Azar, Claudio"
Now showing items 41-60 of 82
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(Marcel Dekker Inc.Taylor & Francis, 1996)The EPR spectra of radicals obtained by electrohytical reduction of 2-nitroimidazole and 4-nitroimidazole were measured in mixed solvents. The behavior of the nitrogen coupling constants with the solvent composition is ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2009-03-01)The interaction between Cu2+ ions and GSH molecules leads to the swift formation of the physiologically occurring Cu(I)-[GSH](2) complex. Recently, we reported that this complex is able to reduce molecular oxygen into ...
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(American Chemical Society, 2008-09)New 1,2,4-thiadiazolylnitrones and furoxanylnitrones were developed and evaluated as neuroprotective agents on a human neuroblastoma (SH-SY5Y) cells model. They inhibited at low micromolar concentrations the oxidative ...
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(2013)A new nitrooxoisoaporphine derivative was synthetized and characterized by cyclic voltammetry and electron spin resonance. Its aqueous solubility was improved by complexes formation with β-cyclodextrin, heptakis(2,6-di-O- ...
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(Elsevier, 2012-10-26)A new nitrooxoisoaporphine derivative was synthetized and characterized by cyclic voltammetry and electron spin resonance. Its aqueous solubility was improved by complexes formation with b-cyclodextrin, heptakis(2,6-di ...
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(ELSEVIER, 2006-08-07)We have recently shown that hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death. It remains unexplored how NFKB is regulated in cultured ...
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(2006)We have recently shown that hyperosmotic stress activates p65/RelB NFκB in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death. It remains unexplored how NFκB is regulated in cultured rat ...
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(MDPI AG, 2014)© 2014 Molecules. The numerous hydroxyl groups available in cyclodextrins are active sites that can form different types of linkages. They can be crosslinked with one another, or they can be derivatized to produce monomers ...
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(2011)The physicochemical properties of 4-hydroxy-7-methoxy-3-phenyl-2H-chromen- 2-one (4HC) and β-cyclodextrins (CDs) inclusion complexes were investigated. The phase solubility profile of 4HC with β-cyclodextrin derivatives ...
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(Bentham Science Publishers B.V., 2015)© 2015 Bentham Science Publishers. Tropical parasitic diseases, especially those produced by protozoan parasites, are a major public health problem in many countries, and their impact in the health burden is significant. ...
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(2009)Four different 5-nitroindazole derivatives (1-4) and its inclusion with Heptakis(2,6-di-O-methyl)-beta-cyclodextrin (DM beta CD) were investigated. The stoichiometric ratios and stability constants describing the extent ...
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(Public Library Science, 2016)Morin (2' A, 3, 4' , 5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to several environmental factors avoid its use in applications like ...
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(Springer, 2020)Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis and other bone illnesses. Some of them have also shown antiparasitic activity. In search of improving the pharmacological profile of ...
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(Royal Society of Chemistry, 2019)In the search for a more effective chemotherapy for the treatment of Chagas' disease and human African trypanosomiasis, caused by Trypanosoma cruzi and Trypanosoma brucei parasites, respectively, the use of organometallic ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2009-12-15)New 5-nitroindazole derivatives were developed and their antichagasic properties studied. Eight compounds (14-18, 20, 26 and 28) displayed remarkable in vitro activities against Trypanosoma cruzi (T. cruzi). Its unspecific ...
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(Elsevier Ltd, 2008-07)Hybrid compounds containing hydrazones and benzofuroxan pharmacophores were designed as potential Trypanosoma cruzi-enzyme inhibitors. The majority of the designed compounds was successfully synthesized and biologically ...
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(Springer, 2013)The present study is focused on the characterization of the interaction between (-)-epigallocatechingallate (EGCG) and cyclodextrins like b-cyclodextrin (bCD), heptakis(2,6 di-O-methyl)-b-cyclodextrin (DMbCD), ...
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(2014)The present study is focused on the characterization of the interaction between (-)-epigallocatechingallate (EGCG) and cyclodextrins like β-cyclodextrin (βCD), heptakis(2,6 di-O-methyl)-β-cyclodextrin (DMβCD), and ...
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(2010)The complexes formed by (±)-4′-hydroxyflavanone (OHFL) and heptakis-(2,6-O-dimethyl)-β-cyclodextrin (DM-β-CD) were obtained using the racemic mixture of OHFL. These complexes were able to be studied due to their ...
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(2012)Complexes formed by (±)-4′-hydroxyflavanone (OHFL) and the cyclodextrins β-cyclodextrin and (2-hydroxypropyl)-β-CD were obtained using the racemic mixture of the OHFL. These complexes were able to be studied due to their ...
