Browsing by Author "Squella Serrano, Juan"
Now showing items 61-80 of 177
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Squella Serrano, Juan; Huerta, M; Bollo Dragnic, Soledad; Pessoa, H; Núñez Vergara, Luis (Elsevier, 1997)The electrochemical reduction of three nitrotetralone derivatives by tast and differential pulse polarography and cyclic voltammetry in a wide pH range was studied. In aqueous media, the reduction of mono- and dinitrotetralone ...
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Bollo Dragnic, Soledad; Gunckel, S.; Núñez Vergara, Luis; Chauviere, G.; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2005-02)The electrochemical behavior of three different megazol analogues substituted at position 4 and their comparison with the parent compound megazol in protic and aprotic media by cyclic voltarnmetry, Tast and differential ...
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Squella Serrano, Juan; Sturm Schaub, Juan; Weiss López, Boris; Bontá, M.; Núñez Vergara, Luis (ELSEVIER SCIENCE, 1999-05-14)The electrochemical reduction of a series of beta-nitrostyrene and beta-methyl-beta-nitrostyrene derivatives: by tast and differential pulse polarography and cyclic voltammetry over a wide pH range was studied. The reduction ...
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Álvarez Lueje, Alejandro; Peña, C.; Núñez Vergara, Luis; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 1998-11)Flutamide, 4-nitro-3-trifluoromethyl-isobutylanilide a synthetic antiandrogenic with therapeutic use in prostatic cancer, is electrochemically studied to propose a new electroanalytical alternative for its quantitative ...
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Álvarez Lueje, Alejandro; Naranjo, Luis; Núñez Vergara, Luis; Squella Serrano, Juan (PERGAMON-ELSEVIER SCIENCE, 1998-01)The anodic and cathodic behavior of nisoldipine, 3-isobutyl-5-methyl-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate, are reported. This drug belongs to the nitroaryl-1,4-dihydropyridine family, known ...
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Electrochemical study of nitrostilbene derivatives: nitro group as a probe of the push-pull effect Bollo Dragnic, Soledad; Núñez Vergara, Luis; Soto Bustamante, Eduardo; Squella Serrano, Juan (ELSEVIER SCIENCE, 2000-09-29)This paper reports electrochemical (tast polarography, differential pulse polarography, cyclic voltammetry) and spectroscopic investigations covering a series of stilbene derivatives having either one or two electron-donating ...
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Squella Serrano, Juan; Núñez Vergara, Luis (1981)
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Squella Serrano, Juan; Bollo Dragnic, Soledad; Fuente Urrutia, Julio de la; Núñez Vergara, Luis (1994)The cyclic voltammetric behavior of nicardipine was studied. Particular attention was directed to the one-electron ArNO2/ArNO2•- couple as measured by the cyclic voltammetric mode in aqueous DMF mixed media. Analysis of ...
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Núñez Vergara, Luis; Sturm Schaub, Juan; Olea Azar, Claudio; Navarrete Encina, Patricio; Bollo Dragnic, Soledad; Squella Serrano, Juan (HARWOOD ACAD PUBL GMBH, 2000)This paper deals with the reactivity of the nitro radical anion electrochemically generated from nitrofurantoin with glutathione. Cyclic voltammetry (CV) and controlled potential electrolysis were used to generate the nitro ...
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Barrientos, C; Navarrete Encina, P.; Squella Serrano, Juan (Electrochemical Soc Inc, 2020)The present studies reveal superoxide radical anion reactivity against synthesized coumarins. Free radicals play an important role in many diseases and they have a protective function also. Therefore, we must keep a balance ...
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Urzúa, J.; Carbajo, J.; Yánez, C.; Marco, J. F.; Squella Serrano, Juan (Springer, 2016)We report that glassy carbon electrodes (GCE) modified with multi-walled carbon nanotubes (MWCNTs) can be derivatized with 2,7-dinitro-9-fluorenone (2,7-NFN). The derivatization procedure involves simple immersion of the ...
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Electrogeneration of nitranion species from nitrofuryl substituted 1,4-dihydropyridine derivatives Argüello da Silva, Jacqueline; Núñez Vergara, Luis; Squella Serrano, Juan (ELSEVIER SCIENCE, 2005-01)We have synthesized and studied the electroreduction of 1,4-dihydropyridine derivatives with a nitrofuryl substituent at 4-position. The one-electron reduction of these compounds in non-aqueous medium generates the ...
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Núñez Vergara, Luis; Salazar González, Ricardo Andrés; Navarrete Encina, Patricio; Camargo Grandón, Rodrigo; Yáñez Soto, Claudia; Squella Serrano, Juan (ELECTROCHEMICAL SOC, 2007)A study of the electrolytic oxidation of three new C-4 nitrofuryl 1,4-dihydropyridines in nonaqueous aprotic medium is presented. Controlled-potential electrolysis (CPE) in dimethylformamide +0.1 M tetrabutyl-ammonium ...
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Squella Serrano, Juan; Jimenez,; Bollo Dragnic, Soledad; Núñez Vergara, Luis (Elsevier Ltd, 1997)Electrochemical studies on 4-(nitrophenyl) substituted 1,4-dihydropyridines of pharmacological importance have allowed us to generate the one-electron reduction product, the nitro radical anion, ArNȮ- 2 , in aprotic media. ...
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Squella Serrano, Juan; Álvarez Lueje, Alejandro; Sturm,; Núñez Vergara, Luis (1993)A differential pulse polarographic method for the identification and quantitative determination of enoxacin is described. The method is based on the electrochemical reduction of the drug at the dropping mercury electrode. ...
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Sierra Rosales, Paulina; Berríos, Cristhian; Miranda Rojas, Sebastián; Squella Serrano, Juan (Elsevier Ltd, 2018)Sunset yellow, Allura red and Ponceau 4R are azo-colorants with similar chemical structures. These colorants were studied by electrochemical methods at a glassy carbon electrode in phosphate buffer solution (pH 7.0), ...
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Squella Serrano, Juan; Perna, S.; Núñez Vergara, Luis (1988)Nifedipine, a calcium antagonist drug, produces a well-defined polarographic wave due to the four-electron, four-proton reduction of the nitro group. This peak is diffusion-controlled and shows a linear dependence on the ...
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Núñez Vergara, Luis; Bollo Dragnic, Soledad; Atria Salas, Ana María; Carbajo, J.; Gunckel, S.; Squella Serrano, Juan (ELECTROCHEMICAL SOC INC, 2002-10)A comprehensive study of the electrochemical characteristics of 2-, 3-, and 4-nitroanisole isomers in three different electrolytic media has been carried out. Furthermore, kinetic characterization of the one-electron ...
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López Alarcón, Camilo; Squella Serrano, Juan; Núñez Vergara, Luis; Báez Guerrero, Hernán; Camargo Grandón, Rodrigo (JOHN WILEY, 2002)A gas chromatography/mass spectrometry (GC/MS) method for the qualitative and quantitative determination of the calcium-channel antagonists C-4-substituted 1,4-dihydropyridines, and their corresponding N-ethyl derivatives, ...
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Álvarez Lueje, Alejandro; Vásquez,; Núñez Vergara, Luis; Squella Serrano, Juan (Taylor and Francis Inc., 1998)An analytical chromatographic method for the determination of nimesulide in pharmaceutical forms has been developed. The method is based on high performance liquid chromatographic (HPLC) and electrochemical detection. ...