Now showing items 728-747 of 2801

    • Ortiz, Andrea C.; Yáñez, Osvaldo; Salas Huenuleo, Edison Sebastián; Morales Montecinos, Javier Octavio (MDPI, 2021)
      Lipid nanocarriers have a great potential for improving the physicochemical characteristics and behavior of poorly water-soluble drugs, such as aqueous dispersibility and oral bioavailability. This investigation presents ...
    • Espinoza, M.; Olea Azar, Claudio; Massif, G.; Villa Litovosky, Alberto (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008-12)
      Reference materials are essential tools to achieve comparability and traceability between measurements. However, reference materials in food matrices are scarce. in this article, the development of a reference material for ...
    • Arazo, Migdalia; Jaque, Néstor; Caro, Nelson; Abugoch James, Lilian; Tapia Villanueva, Cristian (Elsevier, 2020)
      The aim of this study was to develop a scalable crossflow diafiltration/ultrafiltration procedure for quinoa 11S globulin purification starting at the bench scale using Ultra15 centrifugal filter devices. The electrophoretic ...
    • Henríquez, Carolina; Speisky Cosoy, Hernán; Chiffelle, Italo; Valenzuela, Tania; Araya, Manuel; Simpson, Ricardo; Almonacid, Sergio (2010)
      Apple peel is a waste product from dried apple manufacture. The content of phenolic compounds, dietary fiber, and mineral are higher in apple peel, compared to other edible parts of this fruits. The objective of this study ...
    • Tapia, Cristián; Sapag Hagar, Jaime; Muller, Mauricio; Valenzuela, Fernando; Basualto, Carlos; Zunino, Gian Franco (2002)
      The objective of this work was to develop an educational CD-ROM as a complement to the traditional practical-theoretical teaching of unit operations to pharmacy students. The CD-ROM has five main themes. Three of them ...
    • Rodríguez Melis, Alicia; Losada, Vanesa; Larraín Barth, María Angélica; Quitral Robles, Vilma; Vinagre, Julia; Aubourg, Santiago P. (SPRINGER, 2007-08)
      Lipid changes related to quality loss were evaluated during frozen storage of coho salmon for up to 15 months. Biochemical indices concerning lipid hydrolysis (free fatty acids, FFA) and oxidation (peroxide value, PV; ...
    • Betoret, N.; Puente Díaz, Luis; Díaz, M. J.; Pagan, M. J.; García, M. J.; Gras, M. L.; Martínez-Monzo, J.; Fito, P. (ELSEVIER SCI LTD, 2003-02)
      In this study an attempt is made to combine the beneficial effects of probiotics with fruit and vegetables by applying the vacuum impregnation process. Apple cylinders were impregnated either with commercial apple juice ...
    • Zubeldia Brenner, L.; Roselli, C. E.; Recabarren, S. E.; González, M. C.; Lara Peñaloza, Hernán (Wiley, 2016)
      This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal ...
    • Ibacache Figueroa, Mauricio; Sánchez, Gina; Gálvez, Felipe; Pedrozo Cibils, Zully; Humeres Martínez, Claudio; Echevarría, Ghislaine; Duaso, Juan; Hassi, Mario; García Nannig, Lorena; Díaz Araya, Guillermo; Lavandero González, Sergio (ELSEVIER, 2012-04)
      Pharmacological preconditioning limits myocardial infarct size after ischemia/reperfusion. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist used in anesthesia that may have cardioprotective properties against ...
    • Riquelme, Jaime; Westermeier, Francisco; Hall, Andrew R.; Vicencio, Jose; Pedrozo Cibils, Zully; Ibacache, Mauricio; Fuenzalida, Barbara; Sobrevia, Luis; Davidson, Sean M.; Yellon, Derek M.; Sánchez, Gina; Lavandero González, Sergio (Elsevier, 2016)
      The alpha2-adrenergic receptor agonist Dexmedetomidine (Dex) is a sedative medication used by anesthesiologists. Dex protects the heart against ischemia-reperfusion (IR) and can also act as a preconditioning mimetic. The ...
    • Carmona, Danilo J.; Jaque-Olmedo, Pablo; Vöhringer Martínez, Esteban (Springer, 2020)
      Peroxides play a central role in many chemical and biological processes such as the Fenton reaction. The relevance of these compounds lies in the low stability of the O-O bond which upon dissociation results in radical ...
    • Villar, Eugenia del; Vega, Patricio; Gaule, Carlos; Sanchez, Emilio (1990)
      Short or long term diabetes in female rats produced remarkable activation of aminopyrine N-demethylation, inhibition of oestrone and p-nitrophenol glucuronidation and no changes in morphine UDP-glucuronyltransferase activity ...
    • Battiprolu, Pavan K.; López Crisosto, Camila; Wang, Zhao V.; Nemchenko, Andriy; Lavandero González, Sergio; Hill, Joseph A. (2013)
      The incidence and prevalence of diabetes mellitus are both increasing rapidly in societies around the globe. The majority of patients with diabetes succumb ultimately to heart disease, much of which stems from atherosclerotic ...
    • Yempala, Thirumal; Brea, José; Loza, María Isabel; Matthies, Douglas; Zapata Torres, Gerald; Cassels Niven, Bruce (American Chemical Society, 2020)
      The human 5-HT2 receptor subtypes have high sequence identity in their orthosteric ligand-binding domain, and many agonists are poorly selective between the S-HT(2A )and 5-HT2C subtypes. Nevertheless, their activation is ...
    • Garland, María Teresa; Manzur Saffie, Jorge; Moreno N., Yanko; Spodine Spiridonova, Evgenia; Baggio, Ricardo; González, Oscar (MUNKSGAARD INT PUBL LTD, 1996-06-15)
      The title complex, [CuBr2(C12H11N3)], is a monomer and the environment around the Cu2+ ion is that of a square pyramid, with one Br- ion occupying the apical site and the other Br- ion at a basal position.
    • Atria Salas, Ana María; Baggio, Ricardo; Espinosa, N.; Garland, María Teresa; Manzur Saffie, Jorge; Moreno N., Yanko; Spodine Spiridonova, Evgenia (Munksgaard Int. Publ. Ttd., 1994-07-15)
      The crystal structures of dichloro- (2) and dibromo[2-pyridilmethylidene)-2thienylmethylidene)-2-thienylmethylmethyamine-NN'] copper(II) (1) have been determined to investigate the coordination of die metal centre. In ...
    • García, A. M.; Manzur Saffie, Jorge; Spodine Spiridonova, Evgenia; Baggio, Ricardo; Garland, María Teresa (MUNKSGAARD INT PUBL LTD, 1994-12-15)
      The crystal structure of [CUCl2(C12H12N2)] is reported. The complex is monomeric, with the Cu atom coordinated to two N atoms and two Cl- ions. The compound displays simple paramagnetic behaviour.
    • Ortiz Viedma, Jaime; Romero, Nalda; Robert Canales, Paz; Araya, Juan Carlos; López Hernández, J.; Bozzo, C.; Navarrete, E.; Osorio, A.; Ríos, A. (ELSEVIER, 2006)
      The nutritional composition of the edible seaweeds Durvillaea antaretica (frond and stem) and dried Ulva lactuca was determined, including the soluble (SDF), insoluble (IDF) and total (TDF) dietary fiber content, amino ...
    • Fritsch Montero, Rosemarie; Escanilla Durán, Ximena; Goldsack Zambrano, Victoria; Grinberg, Amalia; Navarrete, Araceli; Pérez, Alejandra; Rivera, Caterine; González, Isabel; Sepúlveda, Rodrigo Enrique; Rojas Castillo, María Graciela (Universidad de Chile, Facultad de Medicina, Clínica Psiquiátrica Universitaria, 2006)
      Existen numerosos estudios que muestran que los trastornos mentales comunes son enfermedades frecuentes y discapacitantes. Se ha observado que los estudiantes universitarios constituyen un grupo de riesgo. El objetivo ...
    • Noriega Sepúlveda, Viviana Carolina; Pennanen Saavedra, Christian; Llancaqueo Valeri, Marcelo; Lavandero González, Sergio; Prieto Domínguez, Juan (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2007)
      Las estatinas son fármacos de elección para el tratamiento de hipercolesterolemia. Sin embargo, dado que existe una considerable variabilidad interindividual en la reducción del colesterol, la evaluación farmacogenética ...