Now showing items 81-100 of 177

    • Quesada, Antonio; Argüello da Silva, Jacqueline; Squella Serrano, Juan; Wardell, James L.; Low, John N.; Glidewell, Christopher (BLACKWELL, 2006-01)
      In ethyl 5-cyano-2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3-carboxylate, C15H15N3O5, the molecules are linked into chains by a single N-H (...) O hydrogen bond. The molecules in diethyl 2,6-dimethyl-4-(5-nitr ...
    • Álvarez Lueje, Alejandro; Sturm Schaub, Juan; Núñez Vergara, Luis; Squella Serrano, Juan (PERGAMON-ELSEVIER SCIENCE LTD, 2002-06-01)
      The development of a new HPLC-UV diode array procedure applied to follow the hydrolytic degradation of two well-known 4-nitrophenyl-1,4-dihydropyridine derivatives, nitrendipine and nisoldipine is reported. Hydrolysis of ...
    • Álvarez Lueje, Alejandro; Sturm Schaub, Juan; Squella Serrano, Juan; Núñez Vergara, Luis (PERGAMON-ELSEVIER SCIENCE, 2002-06-01)
      The development of a new HPLC-UV diode array procedure applied to follow the hydrolytic degradation of two well-known 4-nitrophenyl-1,4-dihydropyridine derivatives, nitrendipine and nisoldipine is reported. Hydrolysis of ...
    • Yáñez Soto, Claudia; Basualdo Legüe, Julio Manuel; Jara Ulloa, Paola Andrea; Squella Serrano, Juan (WILEY, 2007-07)
      The interaction of estrone and estradiol with beta-cyclodextrins (beta CD) was investigated by differential pulse voltammetry (DPV) and high-performance liquid chromatography (HPLC) in mixed media. The co-solvent influence ...
    • Squella Serrano, Juan; Núñez Vergara, Luis (1983)
      The interaction of glutathione with ampicillin was investigated by a new a.c. polarographic procedure. Ampicillin was found to interact strongly with glutathione. The stability constants were ascertained from the polarographic ...
    • Núñez Vergara, Luis; Squella Serrano, Juan; Bollo Dragnic, Soledad; Marín Catalán, Rigoberto; Pino, L.; Díaz Araya, Guillermo; Letelier Muñoz, María Eugenia (PERGAMON-ELSEVIER SCIENCE LTD, 1998-01)
      1. Isradipine and lacidipine, two new drugs that are members of the nitro-aryl-1,4-dihydropyridine family, produced inhibition of both growth cultures and oxygen consumption on epimastigotes of Trypanosoma cruzi Tulahuen ...
    • Squella Serrano, Juan; Lemus,; Núñez Vergara, Luis (1995)
      Electrochemical reduction of Ketanserin was studied at different pH and concentrations using polarography and cyclic voltammetry. Ketanserin exhibits two differential pulse polarographic peaks at the dropping mercury ...
    • Jara Ulloa, Paola Andrea; Núñez Vergara, Luis; Squella Serrano, Juan (Wiley-V CH Verlag GMBH, 2007-07)
      Tne reductive electrochemistry of 1-methyl-4-nitro-2-hydroxymethylimidazole, a 4-nitroimidazole derivative, was examined in the presence of surfactants anionic as sodium dodecyl sulfate (SDS), nonionic, Triton-X, Cationic, ...
    • Moscoso,; Carbajo,; Squella Serrano, Juan (Sociedad Chilena de Quimica, 2014)
      © 2014, Sociedad Chilena de Quimica. All rights reserved. We report a voltammetric study of several nitroaromatic compounds such as the drugs: Nifedipine, Nitrendipine, Furnidipine and Nisoldipine in multiwalled carbon ...
    • Moscoso Cabello, Raúl Andrés; Carbajo, J.; Squella Serrano, Juan (Sociedad Chilena de Química, 2014)
      We report a voltammetric study of several nitroaromatic compounds such as the drugs: Nifedipine, Nitrendipine, Furnidipine and Nisoldipine in multiwalled carbon nanotubes (MWCNT) modified electrodes. All the compounds are ...
    • Moscoso, R.; Álvarez Lueje, Alejandro; Squella Serrano, Juan (Elsevier, 2020)
      A novel type of multiwalled carbon nanotube-modified glassy carbon electrode with an entrapped nimesulide drug was constructed. The new electrode surface was characterized by scanning electrochemical microscopy and scanning ...
    • Barrientos, C; Navarrete-Encina, P.A.; Carbajo, J.; Squella Serrano, Juan (Springer, 2018)
      Here, we reveal a different way of doing the voltammetric experiments that considers the electroactive species packaged in the electrodic phase instead of dissolved in solution. In this way, it is possible to obtain ...
    • Squella Serrano, Juan; Barnafi, E.; Perna, S.; Núñez Vergara, Luis (1989)
      A method for the differential-pulse polarographic determination of nifedipine has been developed, based on the electrochemistry of the aromatic nitro group in the drug. Polarography has also been used in studies of the ...
    • Núñez Vergara, Luis; Squella Serrano, Juan; Bollo Dragnic, Soledad; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Aldunate, Jorge; Letelier, María E. (1997)
      A series of nitro aryl 1,4-dihydropyridine derivatives produced inhibition of both cell growth and oxygen consumption on Tulahuen and LQ strains, and clone Dm 28c of epimastigotes of Trypanosoma cruzi. Nicardipine was found ...
    • Núñez Vergara, Luis; Aldunate, Jorge; Letelier Muñoz, María Eugenia; Bollo Dragnic, Soledad; Repetto Scaramelli, Yolanda; Morello Casté, Antonio; Spencer, P. L.; Squella Serrano, Juan (Elsevier, 1995)
      The cyclic voltammetric (CV) behaviour of nifurtimox was studied. The addition of aprotic solvent (DMF) to nifurtimox in an aqueous citrate buffer system was examined. Qualitatively this results in separation of the initial ...
    • Argüello da Silva, Jacqueline; Núñez Vergara, Luis; Bollo Dragnic, Soledad; Squella Serrano, Juan (ELSEVIER SCIENCE SA, 2006-09)
      Three new nitrofuryl substituted 1,4-dihydropyridine derivatives were electrochemically tested in the scope of newly found compounds useful as chemotherapeutic alternative to the Chagas' disease. All the compounds were ...
    • Bontá, M.; Chauviere, G.; Perie, J.; Núñez Vergara, Luis; Squella Serrano, Juan (PERGAMON-ELSEVIER SCIENCE, 2002-09-25)
      We have studied the electrochemical reduction of some nitroimidazoles such as megazol(2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0) and two related derivatives in aprotic media (100% DMF, 0.1 ...
    • Urzúa, J.; Yañez, C.; Carbajo, J.; Mozo, J. D.; Squella Serrano, Juan (Elsevier, 2020)
      We describe nanostructured electrode platforms composed of multiwalled carbon nanotube/glassy carbon electrodes (MWCNT/GCEs) with entrapped nitroaromatic compounds such as 2-nitrofluorene (2-NF), 2-nitro-9- fluorenone ...
    • Merino, M.; Carbajo, J.; Núñez Vergara, Luis; Squella Serrano, Juan (SOCIEDAD CHILENA DE QUIMICA, 2000-03)
      The electrochemical nitroreduction of nitrofurantoin has been studied on carbon paste and glassy carbon electrodes. We can observe a monoelectronic reversible couple ArNO2/ArNO2- and an irreversible peak due to the further ...
    • Bollo Dragnic, Soledad; Núñez Vergara, Luis; Barrientos Vargas, Claudia Marjorie; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2005-09)
      The electrochemical behavior of iodo nitroimidazole derivatives such as 1-methyl-4-iodo-5-nitroimidazole (M-I-NIm) and 1-methyl-2,4-diiodo-5-nitroimidazole (M-I-2-NIm) and the parent compound 1-methyl-5-nitroimidazole ...