Browsing by Author "Chiong Lay, Mario"

Now showing items 1-20 of 72

    • Activity of metalloproteinase-9 is related to oxidative stress in the acute coronary syndrome 
      Bittner, Alex; Castro Agüero, Pablo; Pérez, Osvaldo; Alcaíno Olivares, Hernán Alejandro; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Díaz Araya, Guillermo; Lavandero González, Sergio (OXFORD UNIV PRESS, 2006-08)
      Meeting Abstract
    • Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis - Differential effects of ... 
      Gálvez, A. S.; Ulloa Valenzuela, Juan Alberto; Chiong Lay, Mario; Criollo Céspedes, Alfredo; Eisner, Verónica; Barros, L.; Lavandero González, Sergio (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2003-10-03)
      Cells adapt to hyperosmotic conditions by several mechanisms, including accumulation of sorbitol via induction of the polyol pathway. Failure to adapt to osmotic stress can result in apoptotic cell death. In the present ...
    • Angiotensin II triggers apoptosis in cardiac fibroblast but not in myofibroblast overexpressing the type 1 receptor 
      Díaz Araya, Guillermo; Vivar Sánchez, Raúl; Soto, C.; Copaja, Miguel; Mateluna, F.; Aránguiz Urroz, Pablo Daniel; Muñoz, Juan Pablo; Chiong Lay, Mario; Thomas, W. G.; Lavandero González, Sergio (BLACKWELL PUBLISHING, 2007-07)
      Meeting Abstract
    • ANTIBODIES AGAINST FUNGAL CONIDIA AND ANTIBIOTICS INHIBIT PHENYLALANINE AMMONIA-LYASE ACTIVATION IN CITRUS 
      Quaas, Alex; Chiong Lay, Mario; Roco Arriagada, Ángela; Bravo, Roberto; Seelenfreund Hirsch, Daniela; Pérez Roepke, Luz María (GUSTAV FISCHER VERLAG, 1993-04)
      Antibodies raised against Trichoderma harzianum conidia prevented accumulation of Phenylalanine ammonia-lyase (PAL, E.C. 4.3.1.5.) in Citrus. The observed effect of the antibodies is produced by a delay in the formation ...
    • Apoptosis induced by hyperosmotic stress 
      Eisner, Verónica; Quiroga Lagos, Clara; Criollo Céspedes, Alfredo; Olea Azar, Claudio; Díaz Araya, Guillermo; Chiong Lay, Mario; Lavandero González, Sergio (PERGAMON-ELSEVIER SCIENCE LTD, 2004)
      Meeting Abstract
    • Autofagia del cardiomiocito: ¿Un nuevo mecanismo de adaptación al estrés o de muerte celular? 
      Aránguiz Urroz, Pablo Daniel; Contreras Ferrat, Ariel Eduardo; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo Hernán; Marambio Morales, Paola Angélica; Toro, Bárbara; Sanhueza Muñoz, Carlos Joaquín; Pennanen Saavedra, Christian; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Chiong Lay, Mario; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      Históricamente, la apoptosis y la necrosis han sido consideradas como las dos formas fundamentales de muerte celular. Sin embargo, evidencias recientes sugieren que la muerte celular programada no está confinada sólo a ...
    • Autophagy in cardiovascular biology 
      Lavandero González, Sergio; Chiong Lay, Mario; Rothermel, Beverly A.; Hill, Joseph A. (American Society for Clinical Investigation, 2015)
      Cardiovascular disease is the leading cause of death worldwide. As such, there is great interest in identifying novel mechanisms that govern the cardiovascular response to disease-related stress. First described in failing ...
    • Autophagy mediates tumor necrosis factor-alpha-induced phenotype switching in vascular smooth muscle A7r5 cell line 
      García Miguel, Marina; Riquelme, Jaime A.; Norambuena Soto, Ignacio; Morales, Pablo E.; Sanhueza Olivares, Fernanda; Núñez Soto, Constanza Belén; Mondaca Ruff, David; Cancino Arenas, Nicole; San Martín, Alejandra; Chiong Lay, Mario (Public library science, 2018)
      Vascular smooth muscle cells (VSMC) dedifferentiation from a contractile to a synthetic phenotype contributes to atherosclerosis. Atherosclerotic tissue has a chronic inflammatory component with high levels of tumor necrosis ...
    • BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism 
      Rodríguez, Andrea E.; López Crisosto, Camila; Peña Oyarzún, Daniel; Salas, Daniela; Parra A., Valentina; Quiroga, Clara; Morawe, Tobías; Chiong Lay, Mario; Behl, Christian; Lavandero González, Sergio (Taylor and Francis, 2016)
      Autophagy is mainly regulated by post-translational and lipid modifications of ATG proteins. In some scenarios, the induction of autophagy is accompanied by increased levels of certain ATG mRNAs such as MAP1LC3B/LC3B, ATG5 ...
    • Biochemical characterization of proteins in the crab Homalaspis plana Caracterización bioquímica de las ... 
      Abugoch James, Lilian; Guarda,; Chiong Lay, Mario (1995)
      Homalaspis plana is a crab found in the Pacific Ocean coasts from Guayaquil (Ecuador) all the way down to the Strait of Magellan, including all of the Chilean coast. This crustacean is an important resource because it ...
    • Carvedilol corrects interventricular and interventricular dyssynchrony in chronic heart failure. 
      Castro, Pablo; Mc-Nab, Pablo; Bittner, Alex; Greig, Douglas; Quintana, Juan Carlos; Chiong Lay, Mario; Díaz Araya, Guillermo; Valenzuela, Rodrigo; Vergara, I.; Corbalán, Ramón; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2005-02-01)
      Meeting Abstract
    • Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis 
      Parra Ortíz, María Valentina; Eisner, Verónica; Chiong Lay, Mario; Criollo Céspedes, Alfredo; Moraga, Francisco; García, Alejandra; Haertel, Steffen; Jaimovich Pérez, Enrique; Zorzano, Antonio; Hidalgo Tapia, María Cecilia; Lavandero González, Sergio (ELSEVIER SCIENCE BV, 2008-01-15)
      Aims In cells, mitochondria are organized as a network of interconnected organelles that fluctuate between fission and fusion events (mitochondrial dynamics). This process is associated with cell death. We investigated ...
    • Citrus limon seedlings without functional chloroplasts are unable to induce phenylalanine ammonia-lyase in ... 
      Prieto, Humberto; Chiong Lay, Mario; Garrido, Jorge; Seelenfreund Hirsch, Daniela; Quaas, Alex; Pérez Roepke, Luz María (GUSTAV FISCHER VERLAG, 1997-05)
      A light-dependent bleaching of plastids was induced in lemon seedlings through cultivation in the presence of the herbicide Norfluorazon (NFZ). Also, etiolated seedlings were obtained by cultivation under continuous dark ...
    • Comparative subcellular distribution of apyrase from animal and plant sources. Characterization of microsomal ... 
      Valenzuela,; López,; Depix,; Mancilla,; Kettlun,; Catalán,; Chiong Lay, Mario; Garrido,; Traverso Cori, A. (1989)
      1. 1. Apyrase (ATP: diphosphohydrolase) has been found in the microsomal fraction of rat salivary gland, mammary gland and uterus. 2. 2. This enzyme, already described in plant tissues, is mainly present as a soluble ...
    • Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death ... 
      Aránguiz Urroz, Pablo Daniel; Soto Muñoz, Dagoberto; Contreras Ferrat, Ariel Eduardo; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Montenegro Obregón, José Joaquín; Venegas Pino, Daniel Esteban; Smolic Smolic, Christian; Ayala Jeria, Pedro Segundo; Thomas, W. G.; Lavandero González, Sergio; Díaz Araya, Guillermo (NATURE PUBLISHING GROUP, 2009-05)
      The Angiotensin II (Ang II) type 1 (AT(1)R) and type 2 (AT(2)R) receptors are increased in the heart following myocardial infarction and dilated cardiomyopathy, yet their contribution at a cellular level to compensation ...
    • Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés ... 
      Castro, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Padilla, Ivonne; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Lavandero González, Sergio (Sociedad Española de Cardiología, 2004)
      El carvedilol es un antagonista adrenérgico con acción antioxidante y un demostrado beneficio sobre la mortalidad en insuficiencia cardíaca (IC). El objetivo de este estudio es evaluar, en pacientes con insuficiencia ...
    • Effect of foliar nutrients, fungicides, temperature and metal ions on pectate lyase and endopolygalacturonase ... 
      Aubá, M.; Chiong Lay, Mario; Pérez Roepke, Luz María (Asociación Latinoamericana de Fitopatología, 1993)
      The properties of pectate lyase and endopolygalacturonase, produced by Alternaria alternata isolated from sooty mold infected Citrus trees were studied. These enzymes, related to plant pathogenesis, were obtained from ...
    • Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress ... 
      Castro Agüero, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Padilla, Ivonne; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Lavandero González, Sergio (EDICIONES DOYMA S/L, 2004-11)
      Introduction and objective. Carvedilol is an antioxidant and adrenergic antagonist with demonstrated benefits in terms of mortality from heart failure (HF). The aim of the present study was to evaluate clinical parameters, ...
    • Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure 
      Castro, Pablo; Mac Nab, Paul; Quintana, Juan Pablo; Bittner, Alex; Greig, Douglas; Vergara, I.; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Copaja, Miguel; Díaz Araya, Guillermo; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Alcaíno Olivares, Hernán Alejandro; Lavandero González, Sergio (EXCERPTA MEDICA INC, 2005-07-15)
      Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 ...
    • Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells 
      Antileo, Elmer; Garri, Carolina; Tapia, Victoria; Muñoz, Juan Pablo; Chiong Lay, Mario; Nualart, Francisco; Lavandero González, Sergio; Díaz Fernández, Juan Cristóbal; Núñez González, Marco (American Physiological Society, 2013)
      Ferritin, a food constituent of animal and vegetal origin, is a source of dietary iron. Its hollow central cavity has the capacity to store up to 4,500 atoms of iron, so its potential as an iron donor is advantageous to ...