Browsing by Author "Costa, Edda"
Now showing items 1-8 of 8
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Gai, María Nella; Costa, Edda; Arancibia, Aquiles (DUSTRI-VERLAG DR KARL FEISTLE, 2009-04)Objective: To evaluate the systemic bioavailability of a new controlled release cyclobenzaprine tablet, and the influence of a high fat meal on its bioavailabillty. Subjects, materials and methods: 24 and 12 healthy male ...
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Tapia Villanueva, Cristián; Escobar, Z.; Costa, Edda; Sapag Hagar, Jaime; Valenzuela Lozano, Fernando; Basualto Flores, Carlos; Gai, María Nella; Yazdani-Pedram Zobeiri, Mehrdad (ELSEVIER SCIENCE BV, 2004-01)The aim of this work was to evaluate the possibility of using mixtures and/or polyelectrolyte complexes from both chitosan-alginate and chitosan-carrageenan as prolonged drug release systems. Different dissolution profiles ...
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Tapia Villanueva, Cristián; Sapag Hagar, Jaime; Zunino, Gianfranco; Costa, Edda (1995)The objectives of this work were to establish the utility of chitosan of Chilean production, as an excipient suitable for producing a prolonged-release hydrophilic matrix, and to compare two matrix systems, one with chitosan ...
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Costa, Edda; Correa Briones, Olosmira; Orlandi, Cecilia; Cisternas, Jenny (Real Academia Nacional de Farmacia del Instituto de España, 2003)El objetivo de este trabajo fue evaluar la irritación y el efecto hidratante de los ésteres de AHA's. Se evaluó el efecto irritante de los ésteres málico, láctico y salicílico en comparación a sus respectivos ácidos ...
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Costa, Edda; Villegas Escárate, Carlos Alberto; Donoso Ulloa, Lucrecia; Correa Briones, Olosmira (COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES, DEPT CIENTIFICO, 2007-07)The purpose of this study was to evaluate in vivo the Sun Protection Factor (SPF) of two sunscreens made in a pharmacy, utilizing for such purpose a technique described by the Food and Drug Administration (FDA). This study ...
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Gai, María Nella; Storpirtis, S.; García, P.; Costa, Edda; Thielemann, Ana María; Arancibia, Aquiles (Longman Group, 1992)A lithium carbonate controlled release tablet was evaluated in vivo and compared with a conventional lithium carbonate tablet. Changes in the first formulation were made in order to achieve a better performance. The ...
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Tapia Villanueva, Cristián; Costa, Edda; Terraza, C. A.; Munita, A. M.; Yazdani-Pedram Zobeiri, Mehrdad (GOVI-VERLAG GMBH, 2002-11)The aim of this work was to study the performance of chitosan (CB) grafted with acrylamide (CB-g-A) as prolonged drug release matrix as compared with unmodified chitosan. A non-pH dependent swelling behaviour for the matrix ...
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Tapia Villanueva, Cristián; Corbalán, V.; Costa, Edda; Gai, María Nella; Yazdani-Pedram Zobeiri, Mehrdad (BIOMACROMOLECULES 6(5):2389-2395, 2005-09)The aim of this work was to establish the diltiazem hydrochloride release mechanism from the chitosan-alginate matrix tablet (MCB/AS) and chitosan-carrageenan matrix tablet (MCS/CSI). The weight loss for MCS/CSI is mainly ...