Browsing by Author "Quiroga, Clara"

Now showing items 1-6 of 6

    • BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism 
      Rodríguez, Andrea E.; López Crisosto, Camila; Peña Oyarzún, Daniel; Salas, Daniela; Parra A., Valentina; Quiroga, Clara; Morawe, Tobías; Chiong Lay, Mario; Behl, Christian; Lavandero González, Sergio (Taylor and Francis, 2016)
      Autophagy is mainly regulated by post-translational and lipid modifications of ATG proteins. In some scenarios, the induction of autophagy is accompanied by increased levels of certain ATG mRNAs such as MAP1LC3B/LC3B, ATG5 ...
    • HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol ... 
      Paredes, Felipe; Parra, Valentina; Torrealba, Natalia; Navarro Márquez, Mario F.; Gatica, Damián; Bravo Sagua, Roberto; Troncoso, Rodrigo; Pennanen, Christian; Quiroga, Clara; Chiong Lay, Mario; Caesar, Christa; Taylor, W. Robert; Molgó, Jordi; San Martín, Alejandra; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2016)
      Homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 1 (HERPUD1), an ER resident protein, is upregulated in response to ER stress and Ca2(+) homeostasis deregulation. HERPUD1 ...
    • Hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on ... 
      Eisner, Verónica; Quiroga, Clara; Criollo Céspedes, Alfredo; Eltit Ortega, José Miguel; Chiong Lay, Mario; Parra, Valentina; Hidalgo, Karla; Toro, Barbra; Díaz Araya, Guillermo; Lavandero González, Sergio (ELSEVIER, 2006-06-12)
      NF kappa B is a participant in the process whereby cells adapt to stress. We have evaluated the activation of NF kappa B pathway by hyperosmotic stress in cultured cardiomyocytes and its role in the activation of caspase ...
    • Hyperosmotic stress-dependent NF kappa B activation is regulated by reactive oxygen species and IGF-1 in ... 
      Eisner, Verónica; Criollo Céspedes, Alfredo; Quiroga, Clara; Olea Azar, Claudio; Santibáñez, Juan Francisco; Troncoso, Rodrigo; Chiong Lay, Mario; Díaz Araya, Guillermo; Foncea, Rocío; Lavandero González, Sergio (ELSEVIER, 2006-08-07)
      We have recently shown that hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death. It remains unexplored how NFKB is regulated in cultured ...
    • Polycystin-1 regulates cardiomyocyte mitophagy 
      Ramírez Sagredo, Andrea Soledad; Quiroga, Clara; Garrido Moreno, Valeria Soraya; López Crisosto, Camila; Leiva Navarrete, Sebastián Rolando; Norambuena Soto, Ignacio Estebán; Ortiz Quintero, Jose Jafet; Díaz Vesga, Magda C.; Pérez, William; Hendrickson, Troy; Parra Ortiz, Valentina Maria; Pedrozo Cibils, Zully Rocio Evangelina; Altamirano, Francisco; Chiong Lay, Mario Martin; Lavandero Gonzalez, Sergio Alejandro (Wiley, 2021)
      Polycystin-1 (PC1) is a transmembrane protein found in different cell types, including cardiomyocytes. Alterations in PC1 expression have been linked to mitochondrial damage in renal tubule cells and in patients with ...
    • Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells 
      Mondaca Ruff, David Gonzalo; Quiroga, Clara; Norambuena Soto, Ignacio Estebán; Riquelme Meléndez, Jaime Andrés; San Martin, Alejandra; Bustamante Parraguez, Mario Andrés; Lavandero González, Sergio Alejandro; Chiong Lay, Mario Martín (Wiley, 2022)
      Hypertension is associated with high circulating angiotensin II (Ang II). We have reported that autophagy regulates Ang II-induced vascular smooth muscle cell (VSMC) hypertrophy, but the mechanism mediating this effect is ...