Now showing items 1-4 of 4

    • Arancibia, Aquiles; Gai, María Nella; Paulos, Claudio; Chávez Arrué, Jorge; Pinilla, E.; Angel, N.; Ritschel, W. A. (DUSTRI-VERLAG DR KARL FEISTLE, 2004-06)
      Introduction: A cascade of pathophysiological events occurs with the ascension to high altitude (H). We have performed studies on the effects of exposure to H on the pharmacokinetics of drugs. The hypothesis behind these ...
    • Arancibia, Aquiles; Paulos, Claudio; Chávez Arrué, Jorge; Ritschel, W. A. (DUSTRI-VERLAG DR KARL FEISTLE, 2003-05)
      Introduction: Exposure of the human body to high altitude causes a number of physiological changes. In previous studies, we observed that these changes may alter the pharmacokinetics of drugs. The number of erythrocytes/mm(3) ...
    • Arancibia, Aquiles; Gai, María Nella; Chávez Arrué, Jorge; Paulos, Claudio; Pinilla, E.; González, C.; Villanueva, S.; Ritschel, W. A. (DUSTRI-VERLAG DR KARL FEISTLE, 2005-02)
      Introduction: The exposure to high altitude (H) produces several physiologic alterations which may induce changes in the pharmacokinetics of drugs. This hypothesis has been confirmed in previous studies which suggest that ...
    • Ritschel, W. A.; Paulos, C.; Arancibia, Aquiles; Agrawal, M. A.; Wetzelsberger, K. M.; Lucker, P. W. (PROUS SCIENCE, SA, 1998-03)
      Acetazolamide is recommended for the prophylaxis of acute mountain sickness symptoms which sets in on climbing to high altitudes (H) above 2,500 m. It is primarily excreted unchanged in urine. In a previous study, we ...