Browsing by Author "Soto, Claudio"
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Soto, Claudio (1999)Several lines of evidence suggest that a defective protein folding is a central event in both Alzheimer's and prion disease. Although the two disorders are very different clinically, neuropathologically, and biochemically, ...
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Petchanikow, Cyril; Saborio, Gabriela P.; Anderes, Laurence; Frossard, Marie Jose; Olmedo, Maria I.; Soto, Claudio (2001)A hallmark event in transmissible spongiform encephalopathies is the conversion of the physiological prion protein into the disease-associated isoform. A natural polymorphism at codon 129 of the human prion gene, resulting ...
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Hetz Flores, Claudio; Soto, Claudio (2006)Transmissible Spongiform Encephalopathies are fatal and infectious neurodegenerative diseases characterized by extensive neuronal apoptosis and the accumulation of an abnormally folded form of the cellular prion protein ...