Now showing items 1-19 of 19

    • Calvo Pérez, Víctor; Valenzuela Pedevila, María Antonieta; Traverso Cori, A. (Centro de Perfeccionamiento, Experimentación e Investigaciones Pedagógicas (Chile), 1979)
      No tiene
    • Sandoval, S.; García Nannig, Lorena; Mancilla, Marta; Kettlun, Ana María; Collados, L. E.; Chayet, L.; Alvarez, A.; Traverso Cori, A.; Valenzuela Pedevila, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 1996-05)
      Ecto-nucleotidases may have a role in the regulation of purinoceptor-mediated responses. ATP-diphosphohydrolase or apyrase has been described as an ecto-nucleotidase, which is characterized by a low specificity for its ...
    • Espinosa, Victoria; Galleguillos, M.; Mancilla, Marta; Garrido, J.; Kettlun, Ana María; Collados, L. E.; Chayet, L.; García Nannig, Lorena; Traverso Cori, A.; Valenzuela Pedevila, María Antonieta (ACADEMIC PRESS AUST, 1996-08)
      Extracellular nucleotides interact with specific receptors on the cell surface and are locally metabolized by ecto-nucleotidases. Biochemical characterization of the ATPase and ADPase activities detected in rat heart ...
    • Pieber, M.; Valenzuela Pedevila, María Antonieta; Kettlun, Ana María; Mancilla, Marta; Aranda, E.; Collados, L. E.; Traverso Cori, A. (PERGAMON-ELSEVIER SCIENCE LTD, 1991)
      1. Calcium-stimulated ATPase-ADPase activities were studied in a microsomal fraction of rat placental tissue. 2. The kinetic characteristics correspond to those of ATP-diphosphohydrolase, also known as apyrase (E.C. ...
    • Alvarez, A.; Chayet, L.; Galleguillos, M.; García Nannig, Lorena; Kettlun, Ana María; Collados, L. E.; Traverso Cori, A.; Mancilla, M.; Valenzuela Pedevila, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 1996-01)
      ATP-diphosphohydrolase (or apyrase) hydrolyses nucleoside di- and triphosphates in the presence of millimolar concentration of divalent cations. It is insensitive towards sulfhydryl and aliphatic hydroxyl-selective reagents ...
    • Valenzuela Pedevila, María Antonieta; Kettlun, Ana María; Sandoval, S.; García Nannig, Lorena; Mancilla, Marta; Neckelmann, G.; Chayet, L.; Alvarez, A.; Cuevas, F.; Collados, L. E.; Espinosa, Victoria; Traverso Cori, A.; Bravo, I.; Acevedo, C. G.; Aranda, E. (ASSOC BRAS DIVULG CIENTIFICA, 1996-05)
      ATP-diphosphohydrolase (apyrase, EC 3.6.1.5) has both ATPase and ADPase activity that are stimulated by bivalent metals, with Ca2+ being the most effective. The possible physiological function of this enzyme, associated ...
    • Wink, M. R.; Buffon, A.; Bonan, C. D.; Valenzuela Pedevila, María Antonieta; Sarkis, J. J. K.; Battastini, A. M. O. (PERGAMON-ELSEVIER SCIENCE LTD, 2000-01)
      We have tested several chemical modifiers to investigate which amino acid residues, present in the primary structure of the ecto-apyrase, could be involved in catalysis. Synaptosomes from cerebral cortex of rats were ...
    • Cartier Rovirosa, Luis; García Nannig, Lorena; Kettlun, Ana María; Castañeda, P.; Collados, L. E.; Vásquez, F.; Giraudon, P.; Belin, M. F.; Valenzuela Pedevila, María Antonieta (TAYLOR & FRANCIS AS, 2004-04)
      The cerebrospinal fluid (CSF) is in direct contact with the extracellular space of the CNS, thus biochemical processes in the CNS could potentially be reflected in the CSF. Changes in extracellular matrix (ECM) proteins ...
    • Espinosa, Victoria; Kettlun, Ana María; Zanocco Loyola, Antonio; Cardemil, E.; Valenzuela Pedevila, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 2000-08)
      Chemical modification of potato apyrase suggests that tryptophan residues are close to the nucleotide binding site. K-d values (+/- Ca2+) for the complexes of apyrase with the non-hydrolysable phosphonate adenine nucleotide ...
    • Valenzuela Pedevila, María Antonieta; Cartier Rovirosa, Luis; Collados, L. E.; Kettlun, Ana María; Araya, F.; Concha, C.; Flores, L.; Wolf, M. E.; Mosnaim, A. D. (P J D PUBLICATIONS LTD, 1999)
      We have studied the enzymatic gelatinolytic activity of matrix metalloproteinases (MMPs) present in cerebrospinal fluid (CSF) of samples obtained from 67 individuals, twenty-one nonneurological patients (considered controls) ...
    • Kettlun, Ana María; Alvarez, A.; Quintar, R.; Valenzuela Pedevila, María Antonieta; Collados, L. E.; Aranda, E.; Banda, A.; Chayet, L.; Chiong Lay, Mario; Mancilla, Marta; Traverso Cori, A. (PERGAMON-ELSEVIER SCIENCE LTD, 1994-03)
      1. Kinetic and physico-chemical studies on human placental microsomal fraction confirmed that the ATPase and ADPase activities detected in this fraction correspond to the enzyme ATP-diphosphohydrolase or apyrase (EC 3.6.1.5). ...
    • Kettlun, Ana María; Leyton, Mario; Valenzuela Pedevila, María Antonieta; Mancilla, Marta; Traverso Cori, A. (PERGAMON-ELSEVIER SCIENCE LTD, 1992-06)
      Two forms of ATP-diphosphohydrolase were identified in Solanum tuberosum tuber var. Ultimus. Their hydrolytic activity ratios (ATPase/ADPase) were over 10 for form A and 1 for form B. In the potato tuber homogenate the ...
    • Maldonado, Horacio; Ortiz Riaño, Emilio Javier; Krause, Bernardo; Barriga, Andrés; Medina, Fernando; Pando, M. Elsa; Alberti, Carolina; Kettlun, Ana María; Collados, Lucía; García Nannig, Lorena; Cartier Rovirosa, Luis; Valenzuela Pedevila, María Antonieta (SOC BIOLGIA CHILE, 2008)
      HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is characterized by axonal degeneration of the corticospinal tracts. The specific requirements for transport of proteins and organelles to the distal ...
    • Galleguillos, Marco; Valenzuela Pedevila, María Antonieta; Riquelme González, Raquel; Sanhueza, Emilia M.; Sánchez, Gina; Figueroa, Jorge P.; Llanos Mansilla, Jorge (ELSEVIER SCIENCE INC, 2001-06)
      The fetal llama (Lama glama; a species adapted to live in chronic hypoxia in the highlands of the Andes) did not increase cerebral blood flow and reduce the brain oxygen uptake during hypoxemia. Although nitric oxide (NO) ...
    • Vasconcelos, E. G.; Ferreira, Sergio T.; Técia, M. U.; De Souza, Wanderley; Kettlun, Ana María; Mancilla, Marta; Valenzuela Pedevila, María Antonieta; Verjovski Almeida, S. (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1996-09-06)
      ATP diphosphohydrolase from tegumental membranes of Schistosoma mansoni was solubilized with Triton X-100 plus deoxycholate and separated by preparative nondenaturing polyacrylamide gel electrophoresis. Two isoforms with ...
    • Kettlun, Ana María; Urra, Raúl; Leyton, Mario; Valenzuela Pedevila, María Antonieta; Mancilla, Marta; Traverso Cori, A. (PERGAMON-ELSEVIER SCIENCE LTD, 1992-11)
      Two isoenzymes of ATP-diphosphohydrolase (apyrase) were extracted and purified from S. tuberosum var. Ultimus. Their hydrolytic activity ratios (ATPase/ADPase) were 1.0 (apyrase B) and ca 15.0 (apyrase A). They were ...
    • Calvo Pérez, Víctor; Valenzuela Pedevila, María Antonieta; Traverso Cori, A. (Centro de Perfeccionamiento, Experimentación e Investigaciones Pedagógicas (Chile), 1979)
      No tiene
    • Kettlun Leyton, Andrés; Espinosa, V.; Zanocco Loyola, Antonio; Valenzuela Pedevila, María Antonieta (2000-07)
      Potato apyrase, a soluble ATP-diphosphohydrolase, was purified to homogeneity from several clonal varieties of Solanum tuberosum. Depending on the source of the enzyme, differences in kinetic and physicochemical properties ...
    • Kettlun, Ana María; Cartier Rovirosa, Luis; García Nannig, Lorena; Collados, L. E.; Vásquez, F.; Ramírez, E.; Valenzuela Pedevila, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 2003-05-09)
      The tropical spastic paraparesis or human T-cell lymphotropic virus associated myelopathy (TSP/HAM), has been related with an overexpression of matrix metalloproteinases (MMPs), especially MMP-9. Initial studies of reverse ...