Browsing by Subject "Benzimidazole"

Now showing items 1-2 of 2

    • Synthesis and Biological Screening of Novel Indolalkyl Arenes Targeting the Serotonine Transporter 
      Ojeda Gómez, Claudia; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Carlos David; Recabarren Gajardo, Gonzalo Iván; Méndez Rojas, Claudio (Wiley, 2014)
      A series of functionalized indolylalkylarenes 3–16(a and b) were synthesized and their affinities for the serotonin transporter were investigated in vitro. Compounds 3–12(a and b) were obtained by nucleophilic substitution ...
    • Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene ... 
      Romero Parra, Javier; Mella Ralpán, Jaime; Palmieri, Vittoria; Allara, Marco; Torres, María José; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Escobar, Rossy; Faúndez, Mario; Di Marzo, Vincenzo; Pessoa Mahana, Carlos David (Elsevier, 2016)
      Herein we report the design, synthesis, bioinformatic and biological studies of benzimidazole and benzothiophene derivatives as new cannabinoid receptor ligands. To test the hypothesis that the lack of a hydrogen bond ...