Browsing by Subject "Binding"

Now showing items 1-3 of 3

    • Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles - A new family of ... 
      Mella Raipán, Jaime A.; Lagos, Carlos F.; Recabarren Gajardo, Gonzalo Iván; Espinosa Bustos, Christian; Romero Parra, Javier; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Carlos David (2013)
      A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 ...
    • Spectroscopic studies of the interaction of 3-(2-thienyl)-[1,2,3]triazolo[1,5-a]pyridine with 2,6-dimethy ... 
      Cifuentes, T.; Cayupi, J.; Celis Barros, C.; Zapata Torres, Gerald; Ballesteros Garrido, Rafael; Abarca B., Isabel Margarita; Julián, C. (Royal Soc Chemistry, 2016)
      The inclusion complexation behavior of 3-(2-thienyl)-[1,2,3]triazolo[1,5-a]pyridine ( TTP) with native beta-cyclodextrin and derivatized cyclodextrins was investigated. Stability constants for complexes with 1 : 1 molar ...
    • Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene ... 
      Romero Parra, Javier; Mella Ralpán, Jaime; Palmieri, Vittoria; Allara, Marco; Torres, María José; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Escobar, Rossy; Faúndez, Mario; Di Marzo, Vincenzo; Pessoa Mahana, Carlos David (Elsevier, 2016)
      Herein we report the design, synthesis, bioinformatic and biological studies of benzimidazole and benzothiophene derivatives as new cannabinoid receptor ligands. To test the hypothesis that the lack of a hydrogen bond ...