Browsing by Subject "Blood brain barrier"

Now showing items 1-2 of 2

    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • The effects of gold nanoparticles functionalized with beta-amyloid specific peptides on an in vitro model ... 
      Ruffa, J.; Hüwelb, S.; Kogan Bocian, Marcelo; Simon, Ulrich; Joachim Gallab, Hans (Elsevier, 2017)
      We studied the effect of gold nanoparticle (AuNP) size, surface charge, concentration and morphology on the integrity of the blood–brain barrier (BBB) in a well-established in vitro model set-up. We focused on the effect ...