Browsing by Subject "Cardiomyocytes"

Now showing items 1-3 of 3

    • Advanced glycation and ROS: A link between diabetes and heart failure 
      Rojas, Armando; Mercadal, Enrique; Figueroa, Hector; Morales, Miguel A. (2008)
      Despite many advances achieved to date, heart failure (HF) remains a leading cause of morbidity and mortality. There is a widely-accepted consensus that HF and diabetes are strongly linked by at least 3 mechanisms: associated ...
    • Cavβ2 transcription start site variants modulate calcium handling in newborn rat cardiomyocytes 
      Moreno, Cristian; Hermosilla, Tamara; Morales, Danna; Encina, Matías; Torres-Díaz, Leandro; Díaz, Pablo; Sarmiento, Daniela; Simon, Felipe; Varela, Diego (Springer Verlag, 2015)
      © 2015, Springer-Verlag Berlin Heidelberg.In the heart, the main pathway for calcium influx is mediated by L-type calcium channels, a multi-subunit complex composed of the pore-forming subunit CaV1.2 and the auxiliary ...
    • The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content 
      Shaikh, S.; Troncoso Cotal, Rodrigo; Mondaca Ruff, David; Parra Ortíz, María Valentina; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio (Elsevier, 2018)
      Stromal-interaction molecule 1 (STIM1)-mediated store-operated Ca2+ entry (SOCE) plays a key role in mediating cardiomyocyte hypertrophy, both in vitro and in vivo. Moreover, there is growing support for the contribution ...