Browsing by Subject "Cell signaling"

Now showing items 1-3 of 3

    • Cardiovascular autophagy concepts, controversies, and perspectives 
      Lavandero González, Sergio; Troncoso Cotal, Rodrigo; Rotherme, Beverly; Martinet, Wim; Sadoshima, Junichi; Hill, Joseph (Taylor and Francis Inc., 2013)
      Despite recent scientific and technological advances, cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient response to cellular stress, has been ...
    • Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death 
      Díaz, Ariel; Humeres, Claudio; González, Verónica; Gómez, María Teresa; Montt, Natalia; Sánchez, Gina; Chiong Lay, Mario; García Nannig, Lorena (Academic Press Inc., 2015)
      In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action ...
    • Mitochondria fine-tune the slow Ca2+ transients induced by electrical stimulation of skeletal myotubes 
      Eisner, Verónica; Parra, Valentina; Lavandero González, Sergio; Hidalgo Tapia, María Cecilia; Jaimovich Pérez, Enrique (Elsevier Ltd, 2010)
      Mitochondria sense cytoplasmic Ca2+ signals in many cell types. In mammalian skeletal myotubes, depolarizing stimuli induce two independent cytoplasmic Ca2+ signals: a fast signal associated with contraction and a slow ...