Browsing by Subject "Chagas' disease"

Now showing items 1-3 of 3

    • ESR, electrochemical and ORAC studies of nitro compounds with potential antiprotozoal activity 
      Aravena, María C.; Figueroa, Roberto; Olea Azar, Claudio; Arán, Vicente J. (2010)
      Cyclic Voltammetry (CV) and electron spin resonance (ESR) techniques were used in the investigation of several potentially antiprotozoal nitro derivatives of dihydroquinoxaline and indazole. A self-protonation process ...
    • In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles 
      Boiani, Lucia; Gerpe, Alejandra; Arán, Vicente; Torres de Ortiz, Susana; Serna, Elva; Vera de Bilbao, Ninfa; Sanabria, Luis; Yaluff, Gloria; Nakayama, Héctor; Rojas de Arias, Antonieta; Maya Arango, Juan; Morello, J.; Cerecetto, Hugo; González, Mercedes (2009)
      Previously, we have identified a series of 5-nitroindazoles with good antiprotozoal activities, against Trypanosoma cruzi epimastigotes and Trichomonas vaginalis. Most of them have shown very low unspecific toxicity on ...
    • Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity 
      Hager Ribeiro, Carolina; López Bartolucci, Carolina; Ramírez Toloza, Galia; Valck Calderón, Carolina Eliana; Molina, María Carmen; Aguilar, Lorena; Rodríguez, Margarita; Maldonado, Ismael; Martínez, Ramón; González, Carlos; Troncoso Cotal, Rodrigo; Lavandero González, Sergio; Gingras, Alexandre R.; Schwaeble, Wilhelm; Ferreira, Arturo (PERGAMON-ELSEVIER SCIENCE LTD, 2009-03)
      Trypanosoma cruzi (T cruzi) is the causative agent of Chagas' disease, an endemic and chronic illness that affects 18 million people in Latin America. The mechanisms underlying its pathogenesis are controversial. There is ...