Browsing by Subject "Cytotoxicity"

Now showing items 1-8 of 8

    • A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects 
      Azócar, Manuel; Tamayo, Laura; Vejar, Nelson; Gómez, Grace; Zhou, Xiangrong; Thompsom, George; Cerda, Enrique; Kogan Bocian, Marcelo; Salas, Edison; Páez, Maritza (Kluwer Academic Publishers, 2014)
      We report here a systematic study of the antibacterial behavior of silver nanoparticles coated with fatty acids (oleic: AgNP-O, linoleic: AgNP-L, and palmitic acids: AgNP-P) in water. We have found remarkable differences ...
    • Antibacterial activity and human cell cytotoxic of cobalt (III) complexes with 1,10-phenanthroline and ... 
      Parada Aliste, José; Atria Salas, Ana María; Baggio, Ricardo; Wiese, Guillermo; Lagos, Sebastián; Pavon, Alequis; Rivas, Elizabeth; Navarro, Laura; Corsini, Gino (Sociedad Chilena de Química, 2017)
      The mononuclear cobalt (III) complex derived from 1,10-phenanthroline with lactose [Co(phen)(2)lactose]Cl-2 center dot 3H(2)O (1) has been prepared and its properties have been compared with the sucrose complex ...
    • Facing Chagas' Disease: Trypanocidal Properties of New Coumarin-chalcone Scaffolds 
      Vázquez Rodríguez, Saleta; Guinez, Roberto; Matos, María; Olea Azar, Claudio; Maya Arango, Juan; Uriarte, Eugenio; Santana, Lourdes (Bentham Science, 2016)
      With the aim of finding new chemical entities based on coumarin and chalcone scaffolds, new hybrid compounds 2-5 were designed and synthesized. The trypanocidal activity of these compounds was tested against the epimastigote, ...
    • Molecular insights to alkaline based bio-fabrication of silver nanoparticles for inverse cytotoxicity and ... 
      Verma, Suresh K.; Jha, Ealisha; Panda, Pritam Kumar; Thirumurugan, Arun; Patro, Shubhransu; Parashar, S. K.S.; Suar, Mrutyunjay (Elsevier Ltd, 2018)
      © 2018 Elsevier B.V. High demand for silver nanoparticles due to their extensive applications in different field has raised need of eco-friendly green synthesis with determined biomedical effects. This study proposes a ...
    • Nitrofuran drugs beyond redox cycling: Evidence of Nitroreduction-independent cytotoxicity mechanism 
      Gallardo Garrido, C.; Cho, Y.; Cortés Ríos, J.; Vásquez Velásquez, David; Pessoa Mahana, C. David; Araya Maturana, R.; Pessoa Mahana, Hernán; Faúndez, M. (Elsevier, 2020)
      Nitrofurans (5-nitro-2-hydrazonylfuran as pharmacophore) are a group of widely used antimicrobial drugs but also associated to a variety of side effects. The molecular mechanisms that underlie the cytotoxic effects of ...
    • Photothermal conversion efficiency and cytotoxic effect of gold nanorods stabilized with chitosan, alginate ... 
      Almada, M.; Leal Martínez, B. H.; Hassan, N.; Kogan Bocian, Marcelo; Burboa, M. G.; Topete, A.; Valdez, M. A.; Juarez, J. (Elsevier, 2017)
      Gold nanorods (GNR) use has been proposed in medical applications because of their intrinsic photothermal properties. However, the presence of CTAB molecules adsorbed onto the surface of GNRs results in a highly cytotoxic ...
    • Potent 5-nitrofuran derivatives inhibitors of Trypanosoma cruzi growth: Electrochemical, spectroscopic and ... 
      Aravena, María C.; Olea Azar, Claudio; Cerecetto, Hugo; González, Mercedes; Maya Arango, Juan; Rodríguez Becerra, Jorge (2011)
      Cyclic voltammetry and electron spin resonance techniques were used in the investigation of several potential antiprotozoal containing thiosemicarbazone and carbamate nitrofurans. In the electrochemical behaviour, a ...
    • Structural elucidation and antimicrobial characterization of novel diterpenoids from Fabiana densa var. ramulosa 
      Quaglio, Deborah; Corradi, Silvia; Erazo Giuffra, Silvia; Vergine, Valeria; Berardozzi, Simone; Sciubba, Fabio; Cappiello, Floriana; Crestoni, María Elisa; Ascenzioni, Fiorentina; Imperi, Francesco; Delle Monache, Franco; Mori, Mattia; Loffredo, Maria Rosa; Ghirga, Francesca; Casciaro, Bruno; Botta, Bruno; Mangoni, Maria Luisa (American Chemical Society, 2020)
      Novel diterpenoids were isolated from the extracts of Fabiana densa var. ramulosa and found to display a selective activity against Gram-positive bacterial strains with negligible cytotoxicity toward human keratinocytes. ...