Browsing by Subject "Drug Discovery"
Now showing items 1-14 of 14
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(1991)Boldine shows a concentration-dependent relaxation effect on the rat ileum preparation with a pD2 of 3.77 ± 0.12. The alkaloid also produces a concentration-dependent parallel shift of the curve-response to acetylcholine, ...
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(Informa Healthcare, 1994)Abstractthe antipyretic and antiinflammatory properties of an infusion, a methanol extract, and a purified fraction enriched in sesquiterpenoids, from the aerial parts of maytenus boaria, were evaluated. The fraction ...
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(American Chemical Society, 2014)Tumor cells principally exhibit increased mitochondrial transmembrane potential (Δψm) and altered metabolic pathways. The therapeutic targeting and delivery of anticancer drugs to the mitochondria might improve treatment ...
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(Elsevier, 2017)The authors regret that the affiliation details were incomplete. Full affiliation details for all authors are given above. The authors would like to apologise for any inconvenience caused.
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(1989)A 300 mg controlled-release theophylline formulation was developed as a tablet prepared by wet granulation using the acrylic resins Eudragit S 100(R) and Eudragit RSPM(R). The tablet was compared with a marketed ...
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Dissolution kinetics evaluation of controlled-release tablets containing propranolol hydrochloride (Marcel Dekker Inc., 1999)In the present research, controlled-release propranolol hydrochloride tablets were prepared for twice-daily administration, allowing more uniform plasmatic levels of the drug. Pharmaceutical formulations were prepared with ...
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(Marcel Dekker Inc., 1999)Dissolution profiles of theophylline (TP) from three types of sustained- release (SR) matrix tablets (plastic [PL], lipid [LP], and hydrophilic [HP]) in different dissolution media, with and without enzymes, were established. ...
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(Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA), 2017)
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(2006)The reaction of singlet molecular oxygen with a series of cyclic and acyclic α-diimines was studied. Time-resolved methods were used to measure total reaction rate constants and steady-state methods were used to determine ...
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(2013)A series of novel hydroxy-coumarin-chalcone hybrid compounds 2a-i has been synthesized by employing a simple and efficient methodology. An electrochemical characterization using cyclic voltammetry and ESR spectroscopy were ...
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(Springer New York LLC, 2018)© 2018 American Association of Pharmaceutical Scientists The buccal mucosa appears as a promissory route for biologic drug administration, and pharmaceutical films are flexible dosage forms that can be used in the buccal ...