Browsing by Subject "Drug delivery"
Now showing items 1-20 of 21
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(Bentham Science Publishers B.V., 2014)© 2014, Bentham Science Publishers. Recent advances in nanotechnology and nanobiotechnology have contributed to the development of nanomaterials, able to be used as drug carriers, probes, targets or cytostatic drugs by ...
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(American Scientific Publishers, 2013)With the purpose of obtaining stable and non-toxic nanocomposites with potential biomedical applications we coated gold nanoparticles (AuNP) with chitosan (CHI) and CHI grafted with poly(Nisopropilacrylamide) (PNIPAAm) and ...
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(Elsevier, 2017)As a novel strategy to overcome some of the therapeutic disadvantages of 6-thioguanine (TG) and 6-mercaptopurine (MP), we propose the inclusion of these drugs in beta cyclodextrin (beta CD) to form the complexes beta CD-TG ...
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(MDPI, 2021)In drug delivery, one widely used way of overcoming the biopharmaceutical problems present in several active pharmaceutical ingredients, such as poor aqueous solubility, early instability, and low bioavailability, is the ...
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(Elsevier, 2020)New therapeutics such as antisense oligonucleotides, small interfering RNA and peptide-drug conjugates are taking great relevance in the pharmaceutical industry due to their specificity of action and their improved safety ...
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(MDPI, 2020)Extracellular vesicles (EVs) are important mediators of intercellular communication that participate in many physiological/pathological processes. As such, EVs have unique properties related to their origin, which can be ...
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(Bentham Science, 2016)In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths ...
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(BMC, 2020)Background Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can preferentially accumulate at ...
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(American Scientific Publishers, 2013)There has been an increase in the research towards the use of nanoparticles as a promising tool for nanomedicine, from imagenology, drug and gene delivery, to phototherapy. Little is known regarding the interaction between ...
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(Future Medicine, 2017)Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
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(2010)Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...
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(2013)This paper describes the investigation and development of a novel magnetic drug delivery nanosystem (labeled as MO-20) for cancer therapy. The drug employed was oncocalyxone A (onco A), which was isolated from Auxemma ...
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(Bentham Science Publishers Ltd., 2017)This review focuses on the application of metal nanoparticles in the diagnosis and treatment of Alzheimer's and Parkinson's diseases. Metal nanoparticles present interesting physicochemical properties that can be applied ...
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(BIOMED CENTRAL, 2015)Background: Advances in nanostructure materials are leading to novel strategies for drug delivery and targeting, contrast media for magnetic resonance imaging (MRI), agents for hyperthermia and nanocarriers. Superparamagnetic ...
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(MDPI, 2020)Nanosystems used in pharmaceutical formulations have shown promising results in enhancing the administration of drugs of difficult formulations. In particular, porous silica nanoparticles have demonstrated excellent ...
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(Future Medicine Ltd., 2016)Current strategies for brain diseases are mostly symptomatic and noncurative. Nanotechnology has the potential to facilitate the transport of drugs across the blood-brain barrier and to enhance their pharmacokinetic ...
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(Bentham, 2015)Organic and inorganic nanoparticles show great potential for cancer diagnosis and treatment. Because gastric cancer (GC) represents the second most deadly type of neoplasia worldwide, continued research efforts by scientists ...
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(2007)In this review, we describe the contribution of peptides to the biomedical applications of metallic nanoparticles. We also discuss strategies for the preparation of peptide-nanoparticle conjugates and the synthesis of the ...
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(Dove Medical Press, 2015)An exciting and emerging field in nanomedicine involves the use of gold nanoparticles (AuNPs) in the preclinical development of new strategies for the treatment and diagnosis of brain-related diseases such as neurodegeneration ...
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(MDPI AG, 2018)© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This study describes the in-silico rational design, synthesis and evaluation of cross-linked polyvinyl alcohol hydrogels containing γ-cyclodextrin (γ-CDHSAs) as ...