Browsing by Subject "Epigenetics"
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Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein (Impact Journals LLC, 2020)Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...
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(Lippincott Williams & Wilkins, 2020)BACKGROUND: BET (bromodomain and extraterminal) epigenetic reader proteins, in particular BRD4 (bromodomain-containing protein 4), have emerged as potential therapeutic targets in a number of pathological conditions, ...
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(Baishideng Publishing Group Inc., 2015)The sequence of events associated with the development of gastric cancer has been described as "the gastric precancerous cascade". This cascade is a dynamic process that includes lesions, such as atrophic gastritis, ...