Browsing by Subject "Fibrosis"

Now showing items 1-3 of 3

    • Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension 
      González, Leticia; Novoa, Ulises; Moya, Jackeline; Gabrielli, Luigi; Jalil Milad, Jorge; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio; Ocaranza, María Paz (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
    • Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin ... 
      Ocaranza, Maria Paz; Moya, Jackeline; Barrientos, Victor; Alzamora, Rodrigo; Hevia, Daniel; Morales, Cristobal; Pinto, Melissa; Escudero, Nicolás; García Nannig, Lorena; Novoa, Ulises; Ayala, Pedro; Díaz Araya, Guillermo; Godoy, Ivan; Chiong Lay, Mario; Lavandero González, Sergio; Jalil Milad, Jorge (Lippincott Williams and Wilkins, 2014)
      BACKGROUND:: Little is known about the biological effects of angiotensin-(1-9), but available evidence shows that angiotensin-(1-9) has beneficial effects in preventing/ameliorating cardiovascular remodeling. OBJECTIVE:: ...
    • Pro-fibrotic effect of oxidized LDL in cardiac myofibroblasts 
      Villa, Mónica; Cerda Opazo, Paulina; Jiménez Gallegos, Danica; Garrido Moreno, Valeria; Chiong Lay, Mario; Quest, Andrew F. G.; Toledo, Jorge; García Nannig, Lorena (Elsevier, 2020)
      Inflammatory signals associated with cardiac diseases trigger trans-differentiation of cardiac fibroblasts to cardiac myofibroblasts. Cardiac myofibroblasts are the main cell type involved in the development of cardiac ...