Browsing by Subject "Indole"

Now showing items 1-3 of 3

    • Indole-3-carbaldehyde semicarbazone derivatives: synthesis, characterization, and antibacterial activities 
      Carrasco, Fernando; Hernández, Wilfredo; Chupayo, Óscar; Álvarez, Celedonio M.; Oramas Royo, Sandra; Spodine Spiridonova, Evgenia; Tamariz-Ángeles, Carmen; Olivera Gonzales, Percy; Dávalos, Juan Z. (Hindawi, 2020)
      Four indole-3-carbaldehyde semicarbazone derivatives, 2-((5-bromo-1H-indol-3-yl)methylene)hydrazinecarboxamide (1), 2-((5-chloro-1H-indol-3-yl)methylene)hydrazinecarboxamide (2), 2-((5-methoxy-1H-indol-3-yl)methylene)hyd ...
    • Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying ... 
      Pessoa Mahana, Hernán; Silva Matus, Paul Eduardo; Pessoa Mahana, Carlos David; Chung, Hery; Iturriaga-Vásquez, Patricio; Quiroz, Gabriel; Möller-Acuña, Patricia; Zapata Torres, Gerald; Saitz Barría, Claudio; Araya Maturana, Ramiro; Reyes Parada, Miguel (Wiley, 2017)
      A series of novel 3-indolylpropyl derivatives was synthesized and evaluated for their binding affinities at the serotonin-1A receptor subtype (5-HT1AR) and the 5-HT transporter (SERT). Compounds 11b and 14b exhibited the ...
    • Synthesis of 1-benzyl-3-[4-(aryl-1-piperazinyl) carbonyl]-1H-indoles. Novel ligands with potential D4 ... 
      Pessoa Mahana, Hernán; Cuevas M., Ignacio; Pessoa Mahana, Carlos David; Araya Maturana, Ramiro; Almodovar, Iriux; Saitz Barría, Claudio (2011)
      The synthesis of a series of functionalized 1-Benzyl-3-[4-Aryl-1-piperazingl]carbonyl-1H-Indoles 6(a-f), as a potential new class of bioactive ligands at D4 receptors is reported. The synthetic strategy took place through ...