Browsing by Subject "Mitochondrial fission"

Now showing items 1-3 of 3

    • Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated ... 
      Kalkhoran, Siavash Beikoghli; Kriston-Vizi, Janos; Hernández Resendiz, Sauri; Crespo Avilan, Gustavo E.; Rosdah, Ayeshah A.; Lees, Jarmon G.; Simoes Da Costa, Joanna Rodrigues; Ling, Naomi X. Y.; Holien, Jessica K.; Samangouei, Parisa; Chinda, Kroekkiat; Yap, En Ping; Riquelme Meléndez, Jaime Andrés; Ketteler, Robin; Yellon, Derek M.; Lim, Shiang Y.; Hausenloy, Dereck J. (Oxford University Press, 2022)
      Aims Genetic and pharmacological inhibition of mitochondrial fission induced by acute myocardial ischaemia/reperfusion injury (IRI) has been shown to reduce myocardial infarct size. The clinically used anti-hypertensive ...
    • Mitochondria, myocardial remodeling, and cardiovascular disease 
      Verdejo, Hugo; Campo, Andrea del; Troncoso, Rodrigo; Gutiérrez, Tomás; Toro, Barbra; Quiroga, Clara; Pedrozo Cibils, Zully; Muñoz, Juan; García Nannig, Lorena; Castro, Pablo; Lavandero González, Sergio (2012)
      The process of muscle remodeling lies at the core of most cardiovascular diseases. Cardiac adaptation to pressure or volume overload is associated with a complex molecular change in cardiomyocytes which leads to anatomic ...
    • Mitochondrial fission and autophagy in the normal and diseased heart 
      Iglewski, Myriam; Hill, Joseph A.; Lavandero González, Sergio; Rothermel, Beverly A. (2010)
      Sustained hypertension promotes structural, functional and metabolic remodeling of cardiomyocyte mitochondria. As long-lived, postmitotic cells, cardiomyocytes turn over mitochondria continuously to compensate for changes ...