Browsing by Subject "Mitophagy"

Now showing items 1-4 of 4

    • Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein 
      Gómez, Wileidy; Morales, Rodrigo; Maracaja Coutinho, Vinicius; Parra Ortiz, Valentina; Nassif, Melissa (Impact Journals LLC, 2020)
      Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...
    • Mitochondrial fission and autophagy in the normal and diseased heart 
      Iglewski, Myriam; Hill, Joseph A.; Lavandero González, Sergio; Rothermel, Beverly A. (2010)
      Sustained hypertension promotes structural, functional and metabolic remodeling of cardiomyocyte mitochondria. As long-lived, postmitotic cells, cardiomyocytes turn over mitochondria continuously to compensate for changes ...
    • Novel insights into the pathogenesis of diabetic cardiomyopathy and pharmacological strategies 
      Muñoz Córdova, Felipe Andrés; Hernández Fuentes, Carolina; López Crisosto, Camila; Troncoso, Mayarling; Calle Chalco, Ximena Elena; Guerrero Moncayo, Alejandra; Gabrielli, Luigi; Chiong Lay, Mario; Castro, Pablo F.; Lavandero González, Sergio (Frontiers Media, 2021)
      Diabetic cardiomyopathy (DCM) is a severe complication of diabetes developed mainly in poorly controlled patients. In DCM, several clinical manifestations as well as cellular and molecular mechanisms contribute to its ...
    • Polycystin-1 regulates cardiomyocyte mitophagy 
      Ramírez Sagredo, Andrea Soledad; Quiroga, Clara; Garrido Moreno, Valeria Soraya; López Crisosto, Camila; Leiva Navarrete, Sebastián Rolando; Norambuena Soto, Ignacio Estebán; Ortiz Quintero, Jose Jafet; Díaz Vesga, Magda C.; Pérez, William; Hendrickson, Troy; Parra Ortiz, Valentina Maria; Pedrozo Cibils, Zully Rocio Evangelina; Altamirano, Francisco; Chiong Lay, Mario Martin; Lavandero Gonzalez, Sergio Alejandro (Wiley, 2021)
      Polycystin-1 (PC1) is a transmembrane protein found in different cell types, including cardiomyocytes. Alterations in PC1 expression have been linked to mitochondrial damage in renal tubule cells and in patients with ...