Browsing by Subject "Oxidative stress"
Now showing items 1-15 of 15
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(2008)Despite many advances achieved to date, heart failure (HF) remains a leading cause of morbidity and mortality. There is a widely-accepted consensus that HF and diabetes are strongly linked by at least 3 mechanisms: associated ...
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(Elsevier, 2021)The increased oxidative stress in the acceleration of the aging process and development of the neuronal disorder are the common feature detected in neurodegenerative illness, such as Alzheimer’s disease, Parkinson’s ...
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Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein (Impact Journals LLC, 2020)Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...
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(Ediciones Doyma, S.L., 2004)Introduction and objective. Carvedilol is an antioxidant and adrenergic antagonist with demonstrated benefits in terms of mortality from heart failure (HF). The aim of the present study was to evaluate clinical parameters, ...
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Effects of elderflower extract enriched with polyphenols on antioxidant defense of salmon leukocytes (Elsevier, 2021)Background: In fish farming, the plant extracts containing antioxidant compounds have been added to the diet for enhancing pathogen resistance. In vitro studies evaluating the antioxidant effect of herbal extracts on ...
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(2012)It was examined the efficacy of Monascus purpureus standardized extract (Mp) on the endothelial dysfunction (ED) of rat aortic rings caused by oxidative stress as a consequence of their exposition to a high glucose ...
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(2009)The antioxidant herbal ingredients are xenobiotics for animals, many of them must be biotransformed to be eliminated, especially lipophilic compounds. Biotransformation of such xenobiotics- occurs mainly in the hepatic ...
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(Public Library Science, 2015)In this work, the relationship between the molecular structure of three flavonoids (kaempferol, quercetin and morin), their relative location in microheterogeneous media (liposomes and erythrocyte membranes) and their ...
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(Elsevier, 2016)Homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 1 (HERPUD1), an ER resident protein, is upregulated in response to ER stress and Ca2(+) homeostasis deregulation. HERPUD1 ...
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(Bentham Science Publishers B.V., 2015)© 2015 Bentham Science Publishers. Tropical parasitic diseases, especially those produced by protozoan parasites, are a major public health problem in many countries, and their impact in the health burden is significant. ...
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Microsomal oxidative stress induced by NADPH is inhibited by nitrofurantoin redox biotranformation (Informa Healthcare, 2014)Nitrofurantoin is used in the antibacterial therapy of the urinary tract. This therapy is associated with various adverse eff ects whose mechanisms remain unclear. Diverse studies show that the nitro reductive metabolism ...
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(2012)The process of muscle remodeling lies at the core of most cardiovascular diseases. Cardiac adaptation to pressure or volume overload is associated with a complex molecular change in cardiomyocytes which leads to anatomic ...
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(Frontiers Media, 2022)Down syndrome (DS) is a genetic disorder caused by a trisomy of the human chromosome 21 (Hsa21). Overexpression of Hsa21 genes that encode proteins and non-coding RNAs (ncRNAs) can disrupt several cellular functions and ...
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(2011)Niemann-Pick type C (NPC) is a neurodegenerative disease characterized by the intralysosomal accumulation of cholesterol leading to neuronal apoptosis. We have previously reported the activation of the c-Abl/p73 proapoptotic ...
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(Bentham Science Publ, 2015)Electron spin resonance (ESR), called also electron paramagnetic resonance (EPR) together with the spin trapping technique, has allowed us to study and understand how free radicals are involved in various pathologies. In ...
