Browsing by Subject "Photo acylation"
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Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly (Elsevier, 2015)Dihydroxynaphthyl aryl ketones 1e5 have been evaluated for their abilities to inhibit microtubule assembly and the binding to tubulin. Compounds 3, 4 and 5 displayed competitive inhibition against colchicine binding, and ...