Browsing by Subject "ROCK"

Now showing items 1-2 of 2

    • Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells 
      Mondaca Ruff, David Gonzalo; Quiroga, Clara; Norambuena Soto, Ignacio Estebán; Riquelme Meléndez, Jaime Andrés; San Martin, Alejandra; Bustamante Parraguez, Mario Andrés; Lavandero González, Sergio Alejandro; Chiong Lay, Mario Martín (Wiley, 2022)
      Hypertension is associated with high circulating angiotensin II (Ang II). We have reported that autophagy regulates Ang II-induced vascular smooth muscle cell (VSMC) hypertrophy, but the mechanism mediating this effect is ...
    • Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2 
      Ocaranza, María Paz; Valderas, Patricio; Moya, Jackeline; Gabrielli, Luigi; Godoy, Iván; Córdava, Samuel; Mac Nab, Paul; García Nannig, Lorena; Farías, Luis; Jalil, Jorge E. (BMC, 2020)
      BackgroundThe intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ...