Browsing by Subject "ROS"

Now showing items 1-3 of 3

    • Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents 
      Salgado, Francisco; Moncada Basualto, Mauricio Javier; Pozo Martínez, Josué Santiago; Liempi, Ana; Kemmerling Weis, Ulrike; Maya Arango, Juan Diego; Jaque Olmedo, Pablo César; Borges, Fernanda; Uriarte, Eugenio; Matos, María J.; Olea Azar, Claudio Alberto (Elsevier, 2021)
      Chagas disease is the most widespread contagious tropical disease in Latin America, being an important public health problem. Treatments against this disease are still very ineffective, presenting several side effects. ...
    • Oxoisoaporphines and aporphines: Versatile molecules with anticancer Efects 
      Rodríguez Arce, Esteban; Cancino Rivera, Patricio; Arias Calderón, Manuel; Silva Matus, Paul; Saldías, Marianela (MDPI, 2020)
      Cancer is a disease that involves impaired genome stability with a high mortality index globally. Since its discovery, many have searched for effective treatment, assessing different molecules for their anticancer activity. ...
    • Synthesis and antioxidant study of new polyphenolic hybrid-coumarins 
      Pérez Cruz, Karina Angélica; Moncada-Basualto, Mauricio; Morales Valenzuela, Javier; Barriga González, Germán; Navarrete Encina, Patricio; Núñez Vergara, Luis; Squella Serrano, Juan; Olea Azar, Claudio (Elsevier, 2018-05)
      The antioxidant capacity of hydroxylated coumarins and hydroxybenzoic acids has been widely described. However, there is little information on the antioxidant activity when both systems are functionalized. In this work, ...