Browsing by Subject "TLR4"

Now showing items 1-5 of 5

    • Expression and function of TLR4-induced B1R bradykinin receptor on cardiac fibroblasts 
      Muñoz Rodríguez, Claudia Muriel; Fernández, Samuel; Osorio, Jose Miguel; Olivares, Francisco; Anfossi, Renatto; Bolivar, Samir; Humeres, Claudio; Boza Fuentes, Pía; Vivar, Raúl; Pardo Jiménez, Viviana Gladys; Hemmings, Karen E.; Turner, Neil A.; Díaz Araya, Guillermo (Elsevier, 2018)
      Cardiac fibroblasts (CF) are key cells for maintaining extracellular matrix (ECM) protein homeostasis in the heart, and for cardiac repair through CF-to-cardiac myofibroblast (CMF) differentiation. Additionally, CF play ...
    • Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: ... 
      Boza Fuentes, Pía; Ayala, Pedro; Vivar Sánchez, Raúl; Humeres Martínez, Claudio; Tapia Cáceres, Felipe; Muñoz, Claudia; García Nannig, Lorena; Hermoso Ramello, Marcela; Díaz Araya, Guillermo (Elsevier, 2016)
      Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
    • Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression 
      Olivares Silva, Francisco Javier; Landaeta, Rodolfo; Aránguiz, Pablo; Bolivar, Samir; Humeres Martínez, Claudio; Anfossi, Renatto; Vivar Sánchez, Raúl; Boza Fuentes, Pía; Muñoz Jofré, Claudia; Pardo Jiménez, Viviana Gladys; Peiro, Concepción; Sánchez Ferrer, Carlos; Díaz Araya, Guillermo (Elsevier, 2018)
      Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
    • Lipopolysaccharide activates toll like receptor 4 and prevents cardiac fibroblast to myofibroblast differentiation 
      Bolivar, Samir; Santana, Roxana; Ayala, Pedro; Landaeta, Rodolfo; Boza Fuentes, Pía; Humeres Martínez, Claudio; Vivar Sánchez, Raúl; Muñoz Jofré, Claudia; Pardo, Viviana; Fernández, Samuel; Anfossi, Renatto; Díaz Araya, Guillermo (Springer, 2017)
      Bacterial lipopolysaccharide (LPS) is a known ligand of Toll-like receptor 4 (TLR4) which is expressed in cardiac fibroblasts (CF). Differentiation of CF to cardiac myofibroblasts (CMF) is induced by transforming growth ...
    • Toll-like receptor 4 activation prevents rat cardiac fibroblast death induced by simulated ischemia/reperfusion 
      Parra Flores, Pablo Ignacio; Espitia Corredor, Jenaro Antonio; Espinoza Pérez, Claudio Andrés; Queirolo, Cristian; Ayala, Pedro; Brüggendieck, Francisca; Salas Hernández, Aimee; Pardo Jiménez, Viviana Gladys; Díaz Araya, Guillermo Antonio (Frontiers Media, 2021)
      Death of cardiac fibroblasts (CFs) by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. In in vivo models of myocardial infarction, toll-like receptor 4 (TLR4) activation has been reported as ...