Now showing items 344-363 of 854

    • Santa María Vásquez, Lorena; Aliaga Vera, Solange; Faúndes Gómez, Víctor; Morales Roldán, Paulina; Pugin Aguayo, Ángela; Curotto Liotta, Bianca; Soto Reyes, Paula; Peña, María Ignacia; Salas Aliaga, Isabel; Alliende Rodríguez, María Angélica (Cambridge University Press, 2016)
      Fragile X syndrome (FXS) is the most common form of inherited intellectual disability (ID) and co-morbid autism. It is caused by an amplification of the CGG repeat (>200), which is known as the full mutation, within the ...
    • Baker, Emma K.; Arpone, Marta; Kraan, Claudine; Bui, Minh; Rogers, Carolyn; Field, Michael; Bretherton, Lesley; Ling, Ling; Ure, Alexandra; Cohen, Jonathan; Hunter, Matthew F.; Santa María Vásquez, Lorena; Faúndes Gómez, Víctor; Curotto, Bianca; Morales, Paulina; Trigo, César; Salas, Isabel; Alliende Rodríguez, Angélica; Amor, David J.; Godler, David E. (Nature, 2020)
      Fragile X syndrome (FXS) is caused by a hypermethylated full mutation (FM) expansion with >= 200 CGG repeats, and a decrease in FMR1 mRNA and its protein. However, incomplete silencing from FM alleles has been associated ...
    • Angel, Bárbara; Lera Marques, Lydia; Sánchez Reyes, Hugo; Oyarzún, Amaya; Albala Brevis, Cecilia (Elsevier, 2016)
      Introduction: FokI polymorphismhas been associatedwith obesity and type 2 diabetes (T2D) in somepopulations. Objective: To investigate the frequencies of a genetic polymorphismof Vitamin D receptor (FokI) inpatients with ...
    • Brito, Alex; Mujica Coopman, María; Olivares Grohnert, Manuel; López de Romaña, Daniel; Cori, Héctor; Allen, Lindsay H. (SAGE Publications Inc., 2015)
      Background: The current magnitude of folate and vitamin B-12 deficiency in Latin America and the Caribbean is uncertain. Objective: To summarize data on plasma or serum vitamin B-12 and folate concentrations in Latin ...
    • Rodríguez, Juan M.; Miranda, Dante; Bunout Barnett, Daniel; Ronco Macchiavello, Ana María; Maza Cave, María Pía de la; Hirsch Birn, Sandra (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2015)
      Folic acid (FA) consumption at high levels has been associated with colon cancer risk. Several mechanisms have been proposed to explain this association. The Notch signal pathway has been implicated in the regulation of ...
    • Castillo L., Cecilia; Tur, Josep A.; Uauy Dagach-Imbarack, Ricardo (SOC MEDICA SANTIAGO, 2012-02)
      An increased folate intake may be benefi cial in defi cient populations. However, in women with adequate levels it may not deliver additional benefi ts while it may increase the risk for some forms of cancer. A systematic ...
    • Hertrampf, Eva; Cortés, Fanny (INT LIFE SCIENCES INST NORTH AMERICA, 2004-06)
      Neural tube defects (open spina bifida, anencephaly, and encephalocele) represent the first congenital malformations to be preventable through public health measures such as supplementation and/or food fortification with ...
    • Peñailillo, Reyna; Guajardo, Angélica; Llanos Silva, Miguel; Hirsch Birn, Sandra; Ronco Macchiavello, Ana María (Public Library Science, 2015)
      In the placenta, 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta-HSD2) limits fetal glucocorticoid exposure and its inhibition has been associated to low birth weight. Its expression, encoded by the HSD11B2 gene is ...
    • Correa, Teresa; Reyes Jedlicki, Marcela; Taillie, Lindsey Smith; Corvalán Aguilar, Camila; Dillman Carpentier, Francesca R. (American Public Health Association, 2020)
      Objectives. To study changes in food advertising on television after Chile's food marketing restriction was implemented in June 2016. Methods. Food advertisements shown between 6 AM and 12 AM on the 4 primary broadcast ...
    • Durán, Ana Clara; Mialon, Melissa; Crosbie, Eric; Jensen, Melissa Lorena; Harris, Jennifer L.; Batis, Carolina; Corvalán Aguilar, Camila Luz; Smith Taillie, Lindsey (Wiley, 2021)
      The food environment is a major contributor to unhealthy diets in children and, therefore, to the increasing rates of obesity. Acclaimed by scholars across the world, Latin American countries have been leaders in ...
    • Mialon, M.; Pérez, E.; Corvalán, C.; Monteiro, C.; Jaime, P.; Baeza Scagliusi, F. (Oxford, 2020)
    • Mialon, M; Perez, E; Corvalan, C; Monteiro, C; Jaime, P; Scagliusi, FB (Oxford University Press (OUP), 2020)
    • Mialon, Melissa; Corvalán Aguilar, Camila; Cediel, Gustavo; Scagliusi Baeza, Fernanda; Reyes Jedlicki, Marcela (BMC, 2020)
      Background In the business literature, the term "corporate political activity" (CPA) refers to the political strategies undertaken by corporations to protect or expend their markets, by influencing, directly or indirectly, ...
    • Weisstaub Nuta, Sergio; Curi, K.; Salazar, G.; Anziani, A. (Nature Publishing, 2016-03)
    • Paraje, Guillermo; Montes de Oca Carreño, Daniela Victoria Lucía; Wlasiuk, Juan Marcos; Canales, Mario; Popkin, Barry M. (MDPI, 2022)
      This study evaluates the impact of Chile's innovative law on Food Labeling and Advertising, enacted in June 2016, on employment and real wages and profit margins for the food and beverage manufacturing sectors in the ...
    • Mandakovic Seyler, Dinka; Pulgar Tejo, Rodrigo; Maldonado Soto, Jonathan; Mardones, Wladimir; González Canales, Mauricio; Cubillos, Francisco A.; Cambiazo Ayala, Liliana (MDPI, 2020)
      Autochthonous microorganisms are an important source of the distinctive metabolites that influence the chemical profile of wine. However, little is known about the diversity of fungal communities associated with grape ...
    • Gangiredla, Jayanthi; Rand, Hugh; Benisatto, Daniel; Payne, Justin; Strittmatter, Charles; Sanders, Jimmy; Wolfgang, William J.; Libuit, Kevin; Herrick, James B.; Prarat, Melanie; Toro Ibaceta, Magaly Alejandra; Farrell, Thomas; Strain, Errol (BMC, 2021)
      Background: Processing and analyzing whole genome sequencing (WGS) is computationally intense: a single Illumina MiSeq WGS run produces ~ 1 million 250-base-pair reads for each of 24 samples. This poses significant obstacles ...
    • Guil Guerrero, José Luis; González Fernández, María José; Lyashenko, Svetlana; Fabrikov, Dmitri; Rincón Cervera, Miguel Ángel; Urrestarazu, Miguel; Gómez Mercado, Francisco (Wiley, 2020)
      Thirty Boraginaceae species from different tribes were evaluated in a search of gamma-linolenic (GLA, 18:3n-6) and stearidonic acid (SDA, 18:4n-3)-rich oils. The high GLA percentages were found in the seed oils of Symphytum ...
    • Viana Campos, Ana Cristina; Albala Brevis, Cecilia; Lera Marques, Lydia; Sánchez Reyes, Hugo; Duarte Vargas, Andrea María; Ferreira e Ferreira, Efigenia (Biomed Central, 2015)
      Background: The determinants of self-rated health (SRH) have been widely investigated to explain social differences and gender differences in health. This study aimed to investigate the gender differences in predictors ...
    • Moreno, Ximena; Albala Brevis, Cecilia; Lera Marques, Lydia; Leyton Dinamarca, Bárbara; Angel Badillo, Bárbara Karen; Sánchez, Hugo (Public Library Science, 2018)
      Background This study was aimed to estimate life expectancy (LE), disability-free life expectancy (DFLE) and disabled life expectancy (DLE) among older adults from Santiago, Chile, and to determine the existence of ...