Browsing by Author "Guerrero, Javier"
Now showing items 1-9 of 9
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Cáceres, Mónica; Tobar, Nicolás; Guerrero, Javier; Smith, Patricio C.; Martínez, Jorge (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-02-15)In this study, we demonstrated that tyrosine phosphorylation of EGFR and the autocrine expression of uPA and HB-EGF depend on the activity of c-jun amino-terminal kinase (JNK) in human prostatic DU-145 cells. These cells ...
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Santibañez, J. F.; Olivares, Daniela; Guerrero, Javier; Martínez, Jorge (Wiley-Liss, Inc., 2003-07-04)Mouse-transformed keratinocytes cultured in the presence of transforming growth factor 1 (TGF- 1) acquire an array of morphologic and functional properties that give rise to a migratory phenotype that expresses mesenchymal ...
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Guerrero, Javier; Santibáñez, Juan Francisco; González, Alfonso; Martínez, Jorge (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004-01-01)Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are ubiquitous receptors involved in the control of a variety of cellular processes frequently found altered in cancer cells. ...
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Guerrero, Javier; Santibáñez, Juan Francisco; González, Alfonso; Martínez Winkler, Jorge (Elsevier Inc., 2004)Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are ubiquitous receptors involved in the control of a variety of cellular processes frequently found altered in cancer cells. ...
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Tobar, Nicolás; Guerrero, Javier; Smith, Patricio C.; Martínez, Jorge (NATURE PUBLISHING GROUP, 2010-09-28)BACKGROUND: The influence of the stromal microenvironment on the progression of epithelial cancers has been demonstrated. Unravelling the mechanisms by which stromal cells affect epithelial behaviour will contribute in ...
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Cáceres, Mónica; Guerrero, Javier; Martínez, Jorge (ELSEVIER INC, 2005-09-10)Rho GTPases are overexpressed in human tumors and are involved in a variety of cellular processes such as organization of the actin cytoskeleton, cell-cell contact and malignant transformation. EGFR activation plays a key ...
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Guerrero, Javier; Tobar, Nicolás; Cáceres, Mónica; Espinoza, Lorena; Escobar Oliva, Paula; Dotor, Javier; Smith, Patricio C.; Martínez Winkler, Jorge (Springer Science+Business Media, 2011)In carcinomas such as those of breast, pancreas, stomach, and colon, cancer cells support the expansion of molecular and cellular stroma in a phenomenon termed desmoplasia, which is characterized by a strong fibrotic response. ...
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Guerrero, Javier; Tobar, Nicolás; Cáceres, Mónica; Espinoza, Lorena; Escobar, Paula; Dotor, Javier; Smith, Patricio C.; Martínez, Jorge (Springer, 2010)In carcinomas such as those of breast, pancreas, stomach, and colon, cancer cells support the expansion of molecular and cellular stroma in a phenomenon termed desmoplasia, which is characterized by a strong fibrotic response. ...
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Santibañez, Juan Francisco; Guerrero, Javier; Quintanilla, Miguel; Fabra, Angels; Martínez, Jorge (Elsevier Science (USA), 2002-07-15)Mouse transformed keratinocytes cultured in the presence of transforming growth factor-b1 (TGF-b1) acquire a set ofmorphological and functional properties giving rise to a more motile phenotype that expresses mesenchymal ...